Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD. (Q33591507)

28 July 2017

title

Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD. (English)

1 reference

28 July 2017

Victor Anggono

5

0 references

Irina S Moreira

Irina S Moreira

7

0 references

Anders Bach

Anders Bach

6

0 references

Kristian Strømgaard

Kristian Strømgaard

15

0 references

Christophe Mulle

Christophe Mulle

14

0 references

Harel Weinstein

Harel Weinstein

13

0 references

Ulrik Gether

Ulrik Gether

17

0 references

Richard L. Huganir

12

Richard Huganir

1 reference

28 July 2017

4

Mette Rathje

1 reference

28 July 2017

Thor S Thorsen

1

1 reference

28 July 2017

Kenneth L Madsen

2

1 reference

28 July 2017

Nelson Rebola

3

1 reference

28 July 2017

Nicolai Stuhr-Hansen

8

1 reference

28 July 2017

Tino Dyhring

9

1 reference

28 July 2017

Dan Peters

10

1 reference

28 July 2017

Thijs Beuming

11

1 reference

28 July 2017

Lars Christian B Rønn

16

1 reference

28 July 2017

language of work or name

English

0 references

publication date

14 December 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

published in

1 reference

28 July 2017

volume

107

1 reference

28 July 2017

issue

1

1 reference

28 July 2017

page(s)

413-418

1 reference

Disruption of nNOS-PSD95 protein-protein interaction inhibits acute thermal hyperalgesia and chronic mechanical allodynia in rodents

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Small molecule protein-protein interaction inhibitors as CNS therapeutic agents: current progress and future hurdles.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Optimizing Dvl PDZ domain inhibitor by exploring chemical space.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

PICK1 uncoupling from mGluR7a causes absence-like seizures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Membrane localization is critical for activation of the PICK1 BAR domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

An essential role for PICK1 in NMDA receptor-dependent bidirectional synaptic plasticity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

High-throughput screen for small molecule inhibitors of Mint1-PDZ domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Synaptic plasticity and addiction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

PDZ domain protein-protein interactions: a case study with PICK1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

An antagonist of dishevelled protein-protein interaction suppresses beta-catenin-dependent tumor cell growth.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Discovery of low-molecular-weight ligands for the AF6 PDZ domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Identification of a specific inhibitor of the dishevelled PDZ domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

PICK1 is a calcium-sensor for NMDA-induced AMPA receptor trafficking

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Molecular determinants for the complex binding specificity of the PDZ domain in PICK1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Making protein interactions druggable: targeting PDZ domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

PDZ domain proteins of synapses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Regulation of synaptic strength and AMPA receptor subunit composition by PICK1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Origins of PDZ domain ligand specificity. Structure determination and mutagenesis of the Erbin PDZ domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Interaction of the AMPA receptor subunit GluR2/3 with PDZ domains regulates hippocampal long-term depression.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

PICK1 interacts with and regulates PKC phosphorylation of mGLUR7

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902225107

Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902225107

NHERF (Na+/H+ exchanger regulatory factor) gene mutations in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902225107

Specific involvement in neuropathic pain of AMPA receptors and adapter proteins for the GluR2 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902225107

PICK1-mediated GluR2 endocytosis contributes to cellular injury after neuronal trauma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902225107

Cocaine triggered AMPA receptor redistribution is reversed in vivo by mGluR-dependent long-term depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902225107

A selective irreversible inhibitor targeting a PDZ protein interaction domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902225107

PICK1 and phosphorylation of the glutamate receptor 2 (GluR2) AMPA receptor subunit regulates GluR2 recycling after NMDA receptor-induced internalization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902225107

Beta strand peptidomimetics as potent PDZ domain ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902225107

Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902225107

Targeted in vivo mutations of the AMPA receptor subunit GluR2 and its interacting protein PICK1 eliminate cerebellar long-term depression.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Cerebellar long-term depression requires PKC-regulated interactions between GluR2/3 and PDZ domain-containing proteins.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806717

Rational design of the first small-molecule antagonists of NHERF1/EBP50 PDZ domains

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20018661

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0902225107

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference