The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis (Q33608866)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19892829%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis (English)

1 reference

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11 February 2020

0 references

1

1 reference

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11 February 2020

Ross Chapman

4

1 reference

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11 February 2020

Howard D Lindsay

6

1 reference

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11 February 2020

author name string

Sophie M Cecillon

2

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11 February 2020

Antonio Bonis

3

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11 February 2020

Lawrence F Povirk

5

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11 February 2020

language of work or name

English

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publication date

5 November 2009

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11 February 2020

published in

Nucleic Acids Research

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11 February 2020

volume

38

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11 February 2020

issue

2

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11 February 2020

page(s)

441-454

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describes a project that uses

11 February 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2811014/fullTextXML

inferred from PubMed Central ID database lookup

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Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Ku-dependent and Ku-independent end-joining pathways lead to chromosomal rearrangements during double-strand break repair in Saccharomyces cerevisiae.

21 June 2018

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21 June 2018

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21 June 2018

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Deficient nonhomologous end-joining activity in cell-free extracts from Brca1-null fibroblasts.

21 June 2018

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The Mre11 complex: at the crossroads of dna repair and checkpoint signalling

21 June 2018

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Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

21 June 2018

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Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction

21 June 2018

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21 June 2018

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21 June 2018

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Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome

21 June 2018

1 reference

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Chromosomal stability and the DNA double-stranded break connection

21 June 2018

1 reference

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DNA double-strand breaks: signaling, repair and the cancer connection

21 June 2018

1 reference

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Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe.

21 June 2018

1 reference

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Homogeneous preparations of 3'-phosphoglycolate-terminated oligodeoxynucleotides from bleomycin-treated DNA as verified by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry

21 June 2018

1 reference

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Radiosensitivity in Nijmegen Breakage Syndrome cells is attributable to a repair defect and not cell cycle checkpoint defects.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

A mechanistic basis for Mre11-directed DNA joining at microhomologies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

21 June 2018

1 reference

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Ku-dependent nonhomologous DNA end joining in Xenopus egg extracts

21 June 2018

1 reference

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Double-strand break repair in Ku86- and XRCC4-deficient cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

The scid defect results in much slower repair of DNA double-strand breaks but not high levels of residual breaks.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

End-joining of free radical-mediated DNA double-strand breaks in vitro is blocked by the kinase inhibitor wortmannin at a step preceding removal of damaged 3' termini

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Joining of nonhomologous DNA double strand breaks in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

A post-ribosomal supernatant from activated Xenopus eggs that displays post-translationally regulated oscillation of its cdc2+ mitotic kinase activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Delineation of the role of the Mre11 complex in class switch recombination

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Rejoining of DNA double-strand breaks in vitro by single-strand annealing.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Post-translational activation of non-homologous DNA end-joining in Xenopus oocyte extracts.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811014

Rag mutations reveal robust alternative end joining

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19892829

12 December 2020

inferred from PubMed ID database lookup

DNA-PK-independent rejoining of DNA double-strand breaks in human cell extracts in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19892829

12 December 2020

inferred from PubMed ID database lookup

The DNA-dependent protein kinase catalytic activity regulates DNA end processing by means of Ku entry into DNA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19892829

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1093/NAR/GKP905

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19892829%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19892829%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference