Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency (Q33637391)

24064708

28 July 2017

title

Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency (English)

1 reference

28 July 2017

2

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14 June 2020

Yiqi Seow

5

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14 June 2020

Matthew J. Wood

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14 June 2020

author name string

Haifang Yin

1

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14 June 2020

Hong M Moulton

3

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14 June 2020

Corinne Betts

4

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14 June 2020

Jordan Boutilier

6

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14 June 2020

Qingsong Wang

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14 June 2020

Anthony Walsh

8

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Bernard Lebleu

9

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14 June 2020

publication date

24 September 2013

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24064708

Molecular Therapy. Nucleic acids

28 July 2017

published in

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14 June 2020

volume

2

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14 June 2020

page(s)

e124

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Pip5 transduction peptides direct high efficiency oligonucleotide-mediated dystrophin exon skipping in heart and phenotypic correction in mdx mice.

14 June 2020

cites work

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28 July 2018

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28 July 2018

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Identification of a novel muscle targeting peptide in mdx mice

28 July 2018

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28 July 2018

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Chemically modified cell-penetrating peptides for the delivery of nucleic acids

28 July 2018

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Octa-guanidine morpholino restores dystrophin expression in cardiac and skeletal muscles and ameliorates pathology in dystrophic mdx mice

28 July 2018

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Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer

28 July 2018

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Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice.

28 July 2018

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Cell penetrating peptide conjugates of steric block oligonucleotides

28 July 2018

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Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity

28 July 2018

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Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors.

28 July 2018

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The cationic cell-penetrating peptide CPP(TAT) derived from the HIV-1 protein TAT is rapidly transported into living fibroblasts: optical, biophysical, and metabolic evidence

28 July 2018

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Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles

28 July 2018

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Heparan sulfate: decoding a dynamic multifunctional cell regulator

28 July 2018

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Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype

28 July 2018

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Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study

28 July 2018

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Elucidating cell-penetrating peptide mechanisms of action for membrane interaction, cellular uptake, and translocation utilizing the hydrophobic counter-anion pyrenebutyrate

30 October 2018

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Dose-dependent restoration of dystrophin expression in cardiac muscle of dystrophic mice by systemically delivered morpholino

30 October 2018

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A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.

30 October 2018

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Efficacy of systemic morpholino exon-skipping in Duchenne dystrophy dogs

30 October 2018

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Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function.

30 October 2018

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Effective exon skipping and restoration of dystrophin expression by peptide nucleic acid antisense oligonucleotides in mdx mice

30 October 2018

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Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology

30 October 2018

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Arginine-rich cell penetrating peptides: from endosomal uptake to nuclear delivery

30 October 2018

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Antennapedia and HIV transactivator of transcription (TAT) "protein transduction domains" promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans.

30 October 2018

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30 October 2018

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30 October 2018

Identifiers

DOI

10.1038/MTNA.2013.51

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14 June 2020

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14 June 2020

24064708

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