Computational identification and analysis of orphan assembly-line polyketide synthases (Q33640382)

28 July 2017

title

Computational identification and analysis of orphan assembly-line polyketide synthases (English)

1 reference

28 July 2017

3

Chaitan Khosla

1 reference

28 July 2017

Robert V O'Brien

1

1 reference

28 July 2017

Ronald W Davis

series ordinal

2

1 reference

28 July 2017

Maureen E Hillenmeyer

series ordinal

4

1 reference

28 July 2017

publication date

4 December 2013

1 reference

The Journal of Antibiotics

28 July 2017

published in

1 reference

28 July 2017

volume

67

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28 July 2017

issue

1

1 reference

28 July 2017

page(s)

89-97

1 reference

antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

DoBISCUIT: a database of secondary metabolite biosynthetic gene clusters

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

ClusterMine360: a database of microbial PKS/NRPS biosynthesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Molecular insights into the biosynthesis of guadinomine: a type III secretion system inhibitor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Ascaroside signaling is widely conserved among nematodes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Comparative metabolomics reveals biogenesis of ascarosides, a modular library of small-molecule signals in C. elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

WormBase 2012: more genomes, more data, new website

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

A proteomic survey of nonribosomal peptide and polyketide biosynthesis in actinobacteria.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

NRPSpredictor2--a web server for predicting NRPS adenylation domain specificity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Recent advances in awakening silent biosynthetic gene clusters and linking orphan clusters to natural products in microorganisms.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Molecular insights into Burkholderia pseudomallei and Burkholderia mallei pathogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

SBSPKS: structure based sequence analysis of polyketide synthases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

A flavin-dependent halogenase catalyzes the chlorination step in the biosynthesis of Dictyostelium differentiation-inducing factor 1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

A genome-wide analysis of nonribosomal peptide synthetase gene clusters and their peptides in a Planktothrix rubescens strain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Automated genome mining for natural products.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

The biosynthetic logic of polyketide diversity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Horizontal gene transfer in eukaryotic evolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Strategies to unravel the function of orphan biosynthesis pathways: recent examples and future prospects

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Structure and mechanism of the 6-deoxyerythronolide B synthase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Natural biocombinatorics in the polyketide synthase genes of the actinobacterium Streptomyces avermitilis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Evolutionary implications of bacterial polyketide synthases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

AUGUSTUS: a web server for gene finding in eukaryotes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Gene finding in novel genomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

OrthoMCL: Identification of Ortholog Groups for Eukaryotic Genomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Prokaryotic evolution in light of gene transfer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Cryptosporidium parvum: the first protist known to encode a putative polyketide synthase.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Genetic Contributions to Understanding Polyketide Synthases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Ab initio gene finding in Drosophila genomic DNA

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Improved microbial gene identification with GLIMMER

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

GeneMark.hmm: new solutions for gene finding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Basic local alignment search tool

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Modular organization of genes required for complex polyketide biosynthesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Prediction of gene structure

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028714

Manipulation of Modular Polyketide Synthases.

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.125

MapsiDB: an integrated web database for type I polyketide synthases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.125

Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.125

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.125

CLUSEAN: a computer-based framework for the automated analysis of bacterial secondary metabolite biosynthetic gene clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.125

ClustScan: an integrated program package for the semi-automatic annotation of modular biosynthetic gene clusters and in silico prediction of novel chemical structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.125

Comprehensive analysis of distinctive polyketide and nonribosomal peptide structural motifs encoded in microbial genomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.125

Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.125

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.125

Cloning and heterologous expression of the epothilone gene cluster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.125

Genomics-driven discovery of burkholderic acid, a noncanonical, cryptic polyketide from human pathogenic Burkholderia species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.125

Novel Insights into Evolution of Protistan Polyketide Synthases through Phylogenomic Analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.125

New structural scaffold 14-membered macrocyclic lactone ring for selective inhibitors of cell wall peptidoglycan biosynthesis in Staphylococcus aureus

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24301183

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Studies on a new antibiotic, albocycline. I. Isolation, purification and properties

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24301183

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/JA.2013.125

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference