An ultra-high throughput cell-based screen for wee1 degradation inhibitors (Q33641125)

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8 February 2020

title

An ultra-high throughput cell-based screen for wee1 degradation inhibitors (English)

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8 February 2020

2

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8 February 2020

author name string

Franck Madoux

1

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8 February 2020

Peter Chase

3

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8 February 2020

Jitendra K Mishra

4

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8 February 2020

William R Roush

5

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8 February 2020

Nagi G Ayad

6

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8 February 2020

Peter Hodder

7

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8 February 2020

publication date

26 July 2010

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Journal of Biomolecular Screening

8 February 2020

published in

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8 February 2020

volume

15

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8 February 2020

issue

8

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8 February 2020

page(s)

907-917

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Activation domain-dependent degradation of somatic Wee1 kinase

8 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

A high-throughput functional assay for characterization of gamma-aminobutyric acid(A) channel modulators using cryopreserved transiently transfected cells

21 June 2018

1 reference

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The anaphase promoting complex induces substrate degradation during neuronal differentiation.

21 June 2018

1 reference

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Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screening

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

High-throughput screening assays for the identification of chemical probes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

Cdc25 and Wee1: analogous opposites?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

Utility of large-scale transiently transfected cells for cell-based high-throughput screens to identify transient receptor potential channel A1 (TRPA1) antagonists

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

Systems-level dissection of the cell-cycle oscillator: bypassing positive feedback produces damped oscillations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

Nanoliter homogenous ultra-high throughput screening microarray for lead discoveries and IC50 profiling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

Application of division arrest technology to cell-based HTS: comparison with frozen and fresh cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

Mitotic entry: tipping the balance.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

Identification of metabotropic glutamate receptor antagonists using an automated high-throughput screening system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

Proteasome inhibitors: valuable new tools for cell biologists

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082437

Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain.

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1177%2F1087057110375848

The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20660794

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The clinical significance of Cyclin B1 and Wee1 expression in non-small-cell lung cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20660794

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1177/1087057110375848

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20660794%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

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8 February 2020

PubMed publication ID

20660794

1 reference