IL-27 regulates homeostasis of the intestinal CD4+ effector T cell pool and limits intestinal inflammation in a murine model of colitis (Q33651440)

28 July 2017

title

IL-27 regulates homeostasis of the intestinal CD4+ effector T cell pool and limits intestinal inflammation in a murine model of colitis (English)

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28 July 2017

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8

David Artis

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28 July 2017

Amy E Troy

1

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28 July 2017

Colby Zaph

2

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28 July 2017

Yurong Du

3

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28 July 2017

Betsy C Taylor

4

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28 July 2017

Katherine J Guild

5

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28 July 2017

Christopher A Hunter

6

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28 July 2017

Christiaan J M Saris

7

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28 July 2017

language of work or name

English

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publication date

13 July 2009

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28 July 2017

published in

Journal of Immunology

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28 July 2017

volume

183

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28 July 2017

issue

3

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28 July 2017

page(s)

2037-2044

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Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

28 July 2017

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21 June 2018

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21 June 2018

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21 June 2018

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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

21 June 2018

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21 June 2018

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21 June 2018

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IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Antibodies to interleukin 12 abrogate established experimental colitis in mice

21 June 2018

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IL-10 inhibits cytokine production by activated macrophages

21 June 2018

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21 June 2018

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Essential crosstalk between myeloid and lymphoid cells for development of chronic colitis in myeloid-specific signal transducer and activator of transcription 3-deficient mice

30 October 2018

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30 October 2018

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T helper 1-inducing property of IL-27/WSX-1 signaling is required for the induction of experimental colitis

30 October 2018

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Positive and negative regulation of the IL-27 receptor during lymphoid cell activation.

30 October 2018

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Expression of IL-17 homologs and their receptors in the synovial cells of rheumatoid arthritis patients.

30 October 2018

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Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice.

30 October 2018

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The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection

30 October 2018

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Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis

30 October 2018

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12 December 2020

IL-27R deficiency delays the onset of colitis and protects from helminth-induced pathology in a model of chronic IBD

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12 December 2020

WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection

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12 December 2020

The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity

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12 December 2020

Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells

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12 December 2020

The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis

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12 December 2020

IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38

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12 December 2020

Critical role of IL-17 receptor signaling in acute TNBS-induced colitis

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12 December 2020

TGF-beta, a 'double agent' in the immune pathology war

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12 December 2020

Role of toll-like receptors in spontaneous commensal-dependent colitis

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12 December 2020

Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system

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IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge

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12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.0802918

1 reference

28 July 2017

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28 July 2017

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