Inhibition of the K+ channel KCa3.1 ameliorates T cell-mediated colitis (Q33667663)

28 July 2017

title

Inhibition of the K+ channel KCa3.1 ameliorates T cell-mediated colitis (English)

1 reference

28 July 2017

1 reference

Lie Di

1

1 reference

28 July 2017

Shekhar Srivastava

2

1 reference

28 July 2017

Olga Zhdanova

3

1 reference

28 July 2017

Yi Ding

4

1 reference

28 July 2017

Zhai Li

5

1 reference

28 July 2017

Heike Wulff

6

1 reference

28 July 2017

Maria Lafaille

7

1 reference

28 July 2017

Edward Y Skolnik

8

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28 July 2017

language of work or name

English

0 references

publication date

8 January 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

published in

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28 July 2017

volume

107

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28 July 2017

issue

4

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28 July 2017

page(s)

1541-1546

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A protective function for interleukin 17A in T cell-mediated intestinal inflammation

28 July 2017

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14 July 2018

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T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn's disease.

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Delineation of the clotrimazole/TRAM-34 binding site on the intermediate conductance calcium-activated potassium channel, IKCa1

14 July 2018

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Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences

14 July 2018

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Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant

14 July 2018

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14 July 2018

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Differential Ca2+ influx, KCa channel activity, and Ca2+ clearance distinguish Th1 and Th2 lymphocytes

14 July 2018

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CD45RBhigh CD4+ T cells from IFN-gamma knockout mice do not induce wasting disease

14 July 2018

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14 July 2018

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Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

14 July 2018

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A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

14 July 2018

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14 July 2018

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Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

14 July 2018

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14 July 2018

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The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS

14 July 2018

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Physiological roles of the intermediate conductance, Ca2+-activated potassium channel Kcnn4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0910133107

Disruption of the Gardos channel (KCa3.1) in mice causes subtle erythrocyte macrocytosis and progressive splenomegaly.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0910133107

Histidine phosphorylation of the potassium channel KCa3.1 by nucleoside diphosphate kinase B is required for activation of KCa3.1 and CD4 T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0910133107

Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0910133107

RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F.

21 January 2018

1 reference

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IL-17A directly inhibits TH1 cells and thereby suppresses development of intestinal inflammation

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0910133107

A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease

21 January 2018

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Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080610

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Th1-mediated intestinal inflammation in Crohn's disease may be induced by activation of lamina propria lymphocytes through synergistic stimulation of interleukin-12 and interleukin-18 without T cell receptor engagement

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080610

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Immunology. Decoding calcium signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080610

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0910133107

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference