High glucose-induced O-GlcNAcylated carbohydrate response element-binding protein (ChREBP) mediates mesangial cell lipogenesis and fibrosis: the possible role in the development of diabetic nephropathy (Q33676739)

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English	High glucose-induced O-GlcNAcylated carbohydrate response element-binding protein (ChREBP) mediates mesangial cell lipogenesis and fibrosis: the possible role in the development of diabetic nephropathy	scientific article

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10 March 2020

High glucose-induced O-GlcNAcylated carbohydrate response element-binding protein (ChREBP) mediates mesangial cell lipogenesis and fibrosis: the possible role in the development of diabetic nephropathy (English)

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10 March 2020

diabetic nephropathy

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5

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10 March 2020

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Min-Jung Park

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10 March 2020

Dong-Il Kim

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10 March 2020

Seul-Ki Lim

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10 March 2020

Joo-Hee Choi

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10 March 2020

Kyung-Chul Yoon

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10 March 2020

Soo-Hyun Park

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10 March 2014

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10 March 2020

Journal of Biological Chemistry

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10 March 2020

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10 March 2020

13519-13530

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19

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Recent advances in understanding the biochemical and molecular mechanism of diabetic nephropathy

1 reference

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21 June 2018

Structural renal changes in obesity and diabetes

1 reference

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21 June 2018

A potential role for caveolin-1 in VEGF-induced fibronectin upregulation in mesangial cells: involvement of VEGFR2 and Src

1 reference

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21 June 2018

Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation

1 reference

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21 June 2018

Translocation of HSP27 into liver cancer cell nucleus may be associated with phosphorylation and O-GlcNAc glycosylation

1 reference

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21 June 2018

β-N-Acetylglucosamine (O-GlcNAc) is a novel regulator of mitosis-specific phosphorylations on histone H3

1 reference

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21 June 2018

Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression.

1 reference

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21 June 2018

O-linked β-N-acetylglucosamine supports p38 MAPK activation by high glucose in glomerular mesangial cells

1 reference

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21 June 2018

O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver

1 reference

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21 June 2018

Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease

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21 June 2018

The role of O-linked GlcNAc modification on the glucose response of ChREBP.

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21 June 2018

Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c

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21 June 2018

O-GlcNAc signaling: a metabolic link between diabetes and cancer?

1 reference

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21 June 2018

Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytes

1 reference

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21 June 2018

Nuclear receptor liver X receptor is O-GlcNAc-modified in response to glucose

1 reference

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21 June 2018

Regulation of nuclear import/export of carbohydrate response element-binding protein (ChREBP): interaction of an alpha-helix of ChREBP with the 14-3-3 proteins and regulation by phosphorylation.

1 reference

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21 June 2018

Glucose activates ChREBP by increasing its rate of nuclear entry and relieving repression of its transcriptional activity

1 reference

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21 June 2018

ChREBP: a glucose-activated transcription factor involved in the development of metabolic syndrome

1 reference

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21 June 2018

O-GlcNAc regulates FoxO activation in response to glucose

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21 June 2018

Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy

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21 June 2018

Role of ChREBP in hepatic steatosis and insulin resistance.

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21 June 2018

Increased expression of vascular endothelial growth factor in kidney leads to progressive impairment of glomerular functions.

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21 June 2018

New insights into structural patterns encountered in glomerulosclerosis

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21 June 2018

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21 June 2018

Glucose activation of ChREBP in hepatocytes occurs via a two-step mechanism

1 reference

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21 June 2018

Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1c-dependent pathway

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21 June 2018

Perturbations in O-linked beta-N-acetylglucosamine protein modification cause severe defects in mitotic progression and cytokinesis

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21 June 2018

O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes

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21 June 2018

Calorie restriction modulates renal expression of sterol regulatory element binding proteins, lipid accumulation, and age-related renal disease

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21 June 2018

Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver

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21 June 2018

Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genes

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21 June 2018

Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site

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21 June 2018

Lipids in progression of renal disease

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21 June 2018

Regulation of the expression of lipogenic enzyme genes by carbohydrate

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21 June 2018

Role of dietary lipids and renal eicosanoids on the progression of renal disease.

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21 June 2018

Angiotensin II type 1 receptor blockade to control blood pressure in postmenopausal women: influence of hormone replacement therapy

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Insulin resistance of glycogen synthase mediated by o-linked N-acetylglucosamine.

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Niacin improves renal lipid metabolism and slows progression in chronic kidney disease

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High glucose activates HIF-1-mediated signal transduction in glomerular mesangial cells through a carbohydrate response element binding protein

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Role of sterol regulatory element-binding protein 1 in regulation of renal lipid metabolism and glomerulosclerosis in diabetes mellitus.

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Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVBdb/db mice with type 2 diabetes

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Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes.

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21 January 2018

Evidence of O-linked N-acetylglucosamine in diabetic nephropathy.

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21 January 2018

ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver

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Vascular endothelial growth factor activates MAP kinase and enhances collagen synthesis in human mesangial cells

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Regulation of the expression of the L-type pyruvate kinase gene in adult rat hepatocytes in primary culture

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Proinflammatory gene expression and renal lipogenesis are modulated by dietary protein content in obese Zucker fa/fa rats

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Lipid Droplet Accumulation Is Associated with an Increase in Hyperglycemia-Induced Renal Damage

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10.1074/JBC.M113.530139

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10 March 2020

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10 March 2020

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10 March 2020

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