Lipotoxicity (Q36586503)

15 August 2017

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title

Lipotoxicity (English)

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15 August 2017

Weinberg JM

1

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PubMed ID

16955100

15 August 2017

language of work or name

English

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publication date

6 September 2006

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15 August 2017

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15 August 2017

70

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15 August 2017

1560-1566

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15 August 2017

9

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https://scigraph.springernature.com/pub.10.1038/sj.ki.5001834

15 August 2017

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cites work

Thematic review series: the pathogenesis of atherosclerosis: an interpretive history of the cholesterol controversy, part III: mechanistically defining the role of hyperlipidemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Cellular lipid metabolism and the role of lipids in progressive renal disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Stability of oxidative phosphorylation and structural changes of mitochondria in ischemic rat liver

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Lipotoxicity: when tissues overeat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Diseases of liporegulation: new perspective on obesity and related disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Obesity-initiated metabolic syndrome and the kidney: a recipe for chronic kidney disease?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Triglyceride accumulation protects against fatty acid-induced lipotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Mitochondrial dysfunction and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Beta-cell lipotoxicity: burning fat into heat?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

The mitochondrial uncoupling-protein homologues.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Pancreatic beta-cell lipotoxicity induced by overexpression of hormone-sensitive lipase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

The transcription factor SREBP-1c is instrumental in the development of beta-cell dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Fatty acid homeostasis in the normoxic and ischemic heart

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Downregulation of peroxisome proliferator-activated receptor-alpha gene expression in a mouse model of ischemic cardiomyopathy is dependent on reactive oxygen species and prevents lipotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Palmitate-induced apoptosis can occur through a ceramide-independent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Saturated fatty acid-induced apoptosis in MDA-MB-231 breast cancer cells. A role for cardiolipin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Arachidonic acid causes cell death through the mitochondrial permeability transition. Implications for tumor necrosis factor-alpha aopototic signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Increased renal expression of monocyte chemoattractant protein-1 and osteopontin in ADPKD in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Lipid nephrotoxicity in chronic progressive glomerular and tubulo-interstitial disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Treatment of hyperlipidemia reduces glomerular injury in obese Zucker rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Studies of renal injury III: lipid-induced nephropathy in type II diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Prevention of obesity-linked renal disease: age-dependent effects of dietary food restriction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Partition of unesterified fatty acids in normal and nephrotic syndrome serum and its effect on serum electrophoretic pattern

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Characterization of cationic albumin in minimal change nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Contribution of proteinuria to progressive renal injury: consequences of tubular uptake of fatty acid bearing albumin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Stimulation of proximal tubular cell apoptosis by albumin-bound fatty acids mediated by peroxisome proliferator activated receptor-gamma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Urinary free fatty acids bound to albumin aggravate tubulointerstitial damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Fatty acids exacerbate tubulointerstitial injury in protein-overload proteinuria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Addition of oleic acid to delipidated bovine serum albumin aggravates renal damage in experimental protein-overload nephrosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Pathways to nephron loss starting from glomerular diseases-insights from animal models

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Glomerular injury in analbuminemic rats after subtotal nephrectomy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Role of sterol regulatory element-binding protein 1 in regulation of renal lipid metabolism and glomerulosclerosis in diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVBdb/db mice with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1c-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Calorie restriction modulates renal expression of sterol regulatory element binding proteins, lipid accumulation, and age-related renal disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Lipid accumulation and transforming growth factor-beta upregulation in the kidneys of rats administered angiotensin II.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Dyslipidemia and the progression of renal disease in chronic renal failure patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Uremia-specific alterations in lipid metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Renal insulin resistance syndrome, adiponectin and cardiovascular events in patients with kidney disease: the mild and moderate kidney disease study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Accumulation of nonesterified fatty acids causes the sustained energetic deficit in kidney proximal tubules after hypoxia-reoxygenation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Renal cholesterol accumulation: a durable response after acute and subacute renal insults

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Renal tubular triglyercide accumulation following endotoxic, toxic, and ischemic injury.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Triglyceride accumulation in injured renal tubular cells: alterations in both synthetic and catabolic pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

The mevalonate pathway during acute tubular injury: selected determinants and consequences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Altered sphingomyelinase and ceramide expression in the setting of ischemic and nephrotoxic acute renal failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Etomoxir-induced PPARalpha-modulated enzymes protect during acute renal failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

PPARα ligand protects during cisplatin-induced acute renal failure by preventing inhibition of renal FAO and PDC activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Alterations of PPARalpha and its coactivator PGC-1 in cisplatin-induced acute renal failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Hypoxia inhibits the peroxisome proliferator-activated receptor alpha/retinoid X receptor gene regulatory pathway in cardiac myocytes: a mechanism for O2-dependent modulation of mitochondrial fatty acid oxidation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Metabolomic study of cisplatin-induced nephrotoxicity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Fibrate prevents cisplatin-induced proximal tubule cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Fatty acids enhance membrane permeabilization by pro-apoptotic Bax.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Role of peroxisome proliferator-activated receptor alpha in altered cell cycle regulation in mouse liver.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Insulin resistance in critically ill patients with acute renal failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Intensive insulin therapy in critically ill patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001834

7 January 2021

Identifiers

DOI

10.1038/SJ.KI.5001834

1 reference

PubMed ID

16955100

Dimensions Publication ID

15 August 2017

0 references

1 reference

PubMed ID

16955100