Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation (Q33694463)

28 July 2017

Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation (English)

1 reference

28 July 2017

1 reference

Gijs van Haaften

3

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author name string

Ellen A A Nollen

1

1 reference

28 July 2017

Susana M Garcia

2

1 reference

28 July 2017

Soojin Kim

4

1 reference

28 July 2017

Alejandro Chavez

5

1 reference

28 July 2017

Richard I Morimoto

6

1 reference

28 July 2017

Ronald H A Plasterk

7

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28 July 2017

language of work or name

English

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publication date

14 April 2004

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Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

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28 July 2017

101

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28 July 2017

17

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28 July 2017

6403-6408

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Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Eukaryotic chaperonins: lubricating the folding of WD-repeat proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Tumorigenic mutations in VHL disrupt folding in vivo by interfering with chaperonin binding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

TRiC/CCT cooperates with different upstream chaperones in the folding of distinct protein classes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Dying for a cause: invertebrate genetics takes on human neurodegeneration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Unfolding the role of protein misfolding in neurodegenerative diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Glutamine/proline-rich PQE-1 proteins protect Caenorhabditis elegans neurons from huntingtin polyglutamine neurotoxicity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Toxic proteins in neurodegenerative disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Review: cellular substrates of the eukaryotic chaperonin TRiC/CCT.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Genetic suppression of polyglutamine toxicity in Drosophila

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

CAG repeat number governs the development rate of pathology in Huntington's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404057

Quality control in the endoplasmic reticulum

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307697101

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307697101

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307697101

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307697101

Identification of genes that modify ataxin-1-induced neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307697101

Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307697101

Oxidative stress causes abnormal accumulation of familial amyotrophic lateral sclerosis-related mutant SOD1 in transgenic Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307697101

Polyglutamine protein aggregates are dynamic

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15084750

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0307697101

1 reference

28 July 2017

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1 reference

28 July 2017

1 reference