Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation. (Q33695751)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20852062%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation (English)

1 reference

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14 February 2020

0 references

1

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14 February 2020

Peter Davies

5

1 reference

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14 February 2020

Philippe Marambaud

6

1 reference

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14 February 2020

author name string

Pallavi Chandakkar

2

1 reference

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14 February 2020

Haitian Zhao

3

1 reference

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14 February 2020

Cristina d'Abramo

4

1 reference

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14 February 2020

language of work or name

English

0 references

publication date

17 September 2010

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14 February 2020

1 reference

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14 February 2020

volume

25

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14 February 2020

page(s)

219-231

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14 February 2020

issue

1

1 reference

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Regulation of amyloid precursor protein processing by the Beclin 1 complex

14 February 2020

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Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation

21 June 2018

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AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.

21 June 2018

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21 June 2018

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Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP.

21 June 2018

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AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol

21 June 2018

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21 June 2018

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21 June 2018

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Expanding roles for AMP-activated protein kinase in neuronal survival and autophagy

21 June 2018

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

21 June 2018

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Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis

21 June 2018

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AMPK: an emerging drug target for diabetes and the metabolic syndrome

21 June 2018

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AMPK in the brain: its roles in energy balance and neuroprotection

21 June 2018

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All-you-can-eat: autophagy in neurodegeneration and neuroprotection.

21 June 2018

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PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

21 June 2018

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Targeting the AMPK pathway for the treatment of Type 2 diabetes

21 June 2018

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Autophagy protects neuron from Abeta-induced cytotoxicity

21 June 2018

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Therapeutic potential of resveratrol in Alzheimer's disease

21 June 2018

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Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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AMP-activated protein kinase phosphorylates transcription factors of the CREB family

21 June 2018

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Autophagy, amyloidogenesis and Alzheimer disease

21 June 2018

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Self-eating and self-killing: crosstalk between autophagy and apoptosis

21 June 2018

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AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

21 June 2018

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Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies

21 June 2018

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mTOR and cancer: insights into a complex relationship

21 June 2018

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Regulation of proliferation and gene expression in cultured human aortic smooth muscle cells by resveratrol and standardized grape extracts

21 June 2018

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TOR signaling in growth and metabolism

21 June 2018

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The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

21 June 2018

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Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease

21 June 2018

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Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides.

21 June 2018

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Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation.

21 June 2018

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Amyloid-beta precursor protein processing in neurodegeneration

21 June 2018

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A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations

21 June 2018

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AP-1 functions upstream of CREB to control synaptic plasticity in Drosophila

21 June 2018

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Role of AMP-activated protein kinase in mechanism of metformin action

21 June 2018

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A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

21 June 2018

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Alzheimer's disease: genes, proteins, and therapy

21 June 2018

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 June 2018

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Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase

21 June 2018

1 reference

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The regulation of AMP-activated protein kinase by phosphorylation

21 June 2018

1 reference

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Processing of the beta-amyloid precursor protein and its regulation in Alzheimer's disease

21 June 2018

1 reference

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Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation

21 June 2018

1 reference

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Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells

30 October 2018

1 reference

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AMP-activated protein kinase and autophagy

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20852062

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1096/FJ.10-167361

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20852062%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20852062%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference