Copper(II)-human amylin complex protects pancreatic cells from amylin toxicity (Q33697856)

28 July 2017

Copper(II)-human amylin complex protects pancreatic cells from amylin toxicity (English)

1 reference

28 July 2017

Elizabeth C Lee

1

1 reference

28 July 2017

Emmeline Ha

2

1 reference

28 July 2017

Sanghamitra Singh

3

1 reference

28 July 2017

Linda Legesse

4

1 reference

28 July 2017

Sana Ahmad

5

1 reference

28 July 2017

Elena Karnaukhova

6

1 reference

28 July 2017

Robert P Donaldson

7

1 reference

28 July 2017

Aleksandar M Jeremic

8

1 reference

28 July 2017

language of work or name

English

0 references

publication date

1 August 2013

1 reference

Physical Chemistry Chemical Physics

28 July 2017

1 reference

28 July 2017

15

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28 July 2017

30

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28 July 2017

12558-12571

1 reference

Copper and oxidative stress in the pathogenesis of Alzheimer's disease

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Alzheimer's disease and diabetes: an integrative view of the role of mitochondria, oxidative stress, and insulin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Clustering and internalization of toxic amylin oligomers in pancreatic cells require plasma membrane cholesterol

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: An effect attenuated by phycocyanin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Copper-induced cytotoxicity: reactive oxygen species or islet amyloid polypeptide oligomer formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Reaction rates and mechanism of the ascorbic acid oxidation by molecular oxygen facilitated by Cu(II)-containing amyloid-beta complexes and aggregates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Intracellular shuttling and mitochondrial function of thioredoxin-interacting protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Pancreatic islet amyloidosis, beta-cell apoptosis, and alpha-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Early onset prion disease from octarepeat expansion correlates with copper binding properties

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

New roles for copper metabolism in cell proliferation, signaling, and disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Environmental factors differently affect human and rat IAPP: conformational preferences and membrane interactions of IAPP17-29 peptide derivatives

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Redox reactions of copper complexes formed with different beta-amyloid peptides and their neuropathological [correction of neuropathalogical] relevance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Compound overload of copper and iron in patients with Wilson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Free radicals and antioxidants in normal physiological functions and human disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Thiol reducing compounds prevent human amylin-evoked cytotoxicity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Promotion of oxidative lipid membrane damage by amyloid beta proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Fibrillogenic amylin evokes islet beta-cell apoptosis through linked activation of a caspase cascade and JNK1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

A novel function of monomeric amyloid beta-protein serving as an antioxidant molecule against metal-induced oxidative damage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Alzheimer's amyloid-beta as a preventive antioxidant for brain lipoproteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

New insights on how metals disrupt amyloid beta-aggregation and their effects on amyloid-beta cytotoxicity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Fibrillar islet amyloid polypeptide differentially affects oxidative mechanisms and lipoprotein uptake in correlation with cytotoxicity in two insulin-producing cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

N-acetylcysteine, a cancer chemopreventive agent, causes oxidative damage to cellular and isolated DNA.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Oxidative mechanisms in the toxicity of metal ions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Measurement of protein using bicinchoninic acid

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Association of serum copper levels and glycemic control in patients with type 2 diabetes

21 June 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Role of copper ion in the pathogenesis of type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Diabetes and dietary copper alter 67Cu metabolism and oxidant defense in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Reaction of stabilized Criegee intermediates from ozonolysis of limonene with sulfur dioxide: ab initio and DFT study

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Redox reactions of the α-synuclein-Cu(2+) complex and their effects on neuronal cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Mechanistic studies of Cu(II) binding to amyloid-beta peptides and the fluorescence and redox behaviors of the resulting complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

The amylin peptide implicated in type 2 diabetes stimulates copper-mediated carbonyl group and ascorbate radical formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Nano-scale imaging and dynamics of amylin-membrane interactions and its implication in type II diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Cholesterol regulates assembly of human islet amyloid polypeptide on model membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Identification of ROS using oxidized DCFDA and flow-cytometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Different mechanisms of oxidative stress and neurotoxicity for Alzheimer's A beta(1--42) and A beta(25--35).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Copper(II) inhibits the formation of amylin amyloid in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Amyloid beta-Cu2+ complexes in both monomeric and fibrillar forms do not generate H2O2 catalytically but quench hydroxyl radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Inhibition of human IAPP fibril formation does not prevent beta-cell death: evidence for distinct actions of oligomers and fibrils of human IAPP.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

Novel method for in vivo hydroxyl radical measurement by microdialysis in fetal sheep brain in utero

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041291

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

30 October 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Dynamical diffraction artifacts in Laue microdiffraction images

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

Copper-mediated formation of hydrogen peroxide from the amylin peptide: A novel mechanism for degeneration of islet cells in type-2 diabetes mellitus?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44542A

21 January 2018

1 reference

12 December 2020

Serum copper concentration and coronary heart disease among US adults

1 reference

12 December 2020

Ternary Coordination Complex between Human Serum Albumin, Copper (II), and l-Histidine

1 reference

12 December 2020

Pore formation by the cytotoxic islet amyloid peptide amylin

1 reference

12 December 2020

Coumarin-3-carboxylic acid as a detector for hydroxyl radicals generated chemically and by gamma radiation

1 reference

12 December 2020

The amyloid paradox: amyloid-beta-metal complexes can be neurotoxic and neuroprotective

1 reference

12 December 2020

Prion protein does not redox-silence Cu2+, but is a sacrificial quencher of hydroxyl radicals

1 reference

12 December 2020

Transthyretin amyloidosis and two other aging-related amyloidoses in an aged vervet monkey

1 reference

12 December 2020

Soluble amyloid beta1-28-copper(I)/copper(II)/Iron(II) complexes are potent antioxidants in cell-free systems

1 reference

12 December 2020

Identifiers

DOI

10.1039/C3CP44542A

1 reference

28 July 2017

1 reference

28 July 2017

1 reference