Trafficking of G-protein-coupled receptors to the plasma membrane: insights for pharmacoperone drugs (Q33699210)

28 July 2017

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title

Trafficking of G-protein-coupled receptors to the plasma membrane: insights for pharmacoperone drugs (English)

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G protein-coupled receptor

28 July 2017

main subject

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1

P Michael Conn

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28 July 2017

author name string

Alfredo Ulloa-Aguirre

series ordinal

2

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28 July 2017

publication date

11 December 2009

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Trends in Endocrinology and Metabolism

28 July 2017

published in

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28 July 2017

volume

21

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28 July 2017

issue

3

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28 July 2017

page(s)

190-197

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Converging concepts of protein folding in vitro and in vivo

28 July 2017

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Molecular mechanism of action of pharmacoperone rescue of misrouted GPCR mutants: the GnRH receptor

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Dominant-negative action of disease-causing gonadotropin-releasing hormone receptor (GnRHR) mutants: a trait that potentially coevolved with decreased plasma membrane expression of GnRHR in humans

28 July 2018

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Quality control in the endoplasmic reticulum

28 July 2018

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28 July 2018

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28 July 2018

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30 October 2018

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'Effective inefficiency': cellular control of protein trafficking as a mechanism of post-translational regulation.

30 October 2018

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Regulation of G protein-coupled receptor trafficking by inefficient plasma membrane expression: molecular basis of an evolved strategy

30 October 2018

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Pharmacologic chaperones as a potential treatment for X-linked nephrogenic diabetes insipidus

30 October 2018

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Intracellular entrapment of wild-type TSH receptor by oligomerization with mutants linked to dominant TSH resistance.

30 October 2018

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30 October 2018

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Parallel regulation of membrane trafficking and dominant-negative effects by misrouted gonadotropin-releasing hormone receptor mutants

30 October 2018

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Pharmacological chaperones: potential treatment for conformational diseases.

30 October 2018

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Human loss-of-function gonadotropin-releasing hormone receptor mutants retain wild-type receptors in the endoplasmic reticulum: molecular basis of the dominant-negative effect

30 October 2018

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Misrouted cell surface GnRH receptors as a disease aetiology for congenital isolated hypogonadotrophic hypogonadism

30 October 2018

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Rescue of hypogonadotropic hypogonadism-causing and manufactured GnRH receptor mutants by a specific protein-folding template: misrouted proteins as a novel disease etiology and therapeutic target

30 October 2018

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Conserved mammalian gonadotropin-releasing hormone receptor carboxyl terminal amino acids regulate ligand binding, effector coupling and internalization

30 October 2018

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Molecular basis of hypogonadotropic hypogonadism: restoration of mutant (E(90)K) GnRH receptor function by a deletion at a distant site

30 October 2018

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Addition of catfish gonadotropin-releasing hormone (GnRH) receptor intracellular carboxyl-terminal tail to rat GnRH receptor alters receptor expression and regulation

30 October 2018

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12 December 2020

Influence of a species-specific extracellular amino acid on expression and function of the human gonadotropin-releasing hormone receptor

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12 December 2020

Disease-causing V(2) vasopressin receptors are retained in different compartments of the early secretory pathway

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12 December 2020

In vitro coexpression and pharmacological rescue of mutant gonadotropin-releasing hormone receptors causing hypogonadotropic hypogonadism in humans expressing compound heterozygous alleles

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A dominant-negative human growth hormone-releasing hormone (GHRH) receptor splice variant inhibits GHRH binding

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Modeling and molecular dynamics simulation of the human gonadotropin-releasing hormone receptor in a lipid bilayer

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12 December 2020

Structure-activity relations of successful pharmacologic chaperones for rescue of naturally occurring and manufactured mutants of the gonadotropin-releasing hormone receptor

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12 December 2020

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12 December 2020

10.1016/J.TEM.2009.11.003

Identifiers

DOI

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28 July 2017

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28 July 2017

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