Functional role of p21 during the cellular response to stress. (Q33706929)

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11 December 2019

review article

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title

Functional role of p21 during the cellular response to stress (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10440238%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

author name string

M Gorospe

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10440238%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

X Wang

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10440238%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

N J Holbrook

series ordinal

3

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11 December 2019

publication date

1 January 1999

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11 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10440238%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

volume

7

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11 December 2019

issue

4-6

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11 December 2019

page(s)

377-385

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Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPbeta

11 December 2019

cites work

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12 December 2020

WAF1/CIP1 increases the susceptibility of p53 non-functional malignant glioma cells to cisplatin-induced apoptosis.

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12 December 2020

p21(waf1) mRNA contains a conserved element in its 3'-untranslated region that is bound by the Elav-like mRNA-stabilizing proteins.

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12 December 2020

Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21(WAF1/Cip1) by STAT5

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12 December 2020

Cyclins, cyclin-dependent kinases and cdk inhibitors: implications in cell cycle control and cancer

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12 December 2020

Loss of p21Waf1/Cip1 sensitizes tumors to radiation by an apoptosis-independent mechanism.

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12 December 2020

Relationships between G1 arrest and stability of the p53 and p21Cip1/Waf1 proteins following gamma-irradiation of human lymphoma cells

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12 December 2020

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

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12 December 2020

Overexpression of p21WAF1/CIP1 induces growth arrest, giant cell formation and apoptosis in human breast carcinoma cell lines.

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12 December 2020

p21WAF1 induces permanent growth arrest and enhances differentiation, but does not alter apoptosis in PC12 cells

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12 December 2020

Posttranscriptional stabilization underlies p53-independent induction of p21WAF1/CIP1/SDI1 in differentiating human leukemic cells

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12 December 2020

Proteasome-dependent regulation of p21WAF1/CIP1 expression

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12 December 2020

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

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12 December 2020

Regulation of p21WAF1/CIP1 expression by p53-independent pathways.

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12 December 2020

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

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12 December 2020

The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells

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12 December 2020

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

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12 December 2020

Repair Defect in p21 WAF1/CIP1 -/- human cancer cells

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12 December 2020

The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival

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12 December 2020

A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation

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12 December 2020

Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice

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12 December 2020

Cell cycle control and cancer

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12 December 2020

WAF1, a potential mediator of p53 tumor suppression

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12 December 2020

Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

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12 December 2020

Role of p21 in prostaglandin A2-mediated cellular arrest and death.

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12 December 2020

Effects of a recombinant adenovirus expressing WAF1/Cip1 on cell growth, cell cycle, and apoptosis.

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12 December 2020

Radiation-induced cell cycle arrest compromised by p21 deficiency

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12 December 2020

The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells

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12 December 2020

IFNalpha induces the expression of the cyclin-dependent kinase inhibitor p21 in human prostate cancer cells

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12 December 2020

CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein

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12 December 2020

p21(Waf1/Cip1) protects against p53-mediated apoptosis of human melanoma cells

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12 December 2020

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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12 December 2020

Activation of p21WAF1/Cip1 expression by a temperature-sensitive mutant of human p53 does not lead to apoptosis.

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12 December 2020

Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis

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12 December 2020

AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression

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12 December 2020

DNA damage induces p21 protein expression by inhibiting ubiquitination in ML-1 cells

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12 December 2020

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

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12 December 2020

CCAAT/enhancer binding protein alpha regulates p21 protein and hepatocyte proliferation in newborn mice

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12 December 2020

Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein

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12 December 2020

Attenuation of WAF1/Cip1 expression by an antisense adenovirus expression vector sensitizes glioblastoma cells to apoptosis induced by chemotherapeutic agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin.

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12 December 2020

p21 is a universal inhibitor of cyclin kinases

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12 December 2020

Redox-Mediated Regulation of p21Waf1/Cip1 Expression Involves a Post-Transcriptional Mechanism and Activation of the Mitogen-Activated Protein Kinase Pathway

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12 December 2020

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

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12 December 2020

Protective role of p21(Waf1/Cip1) against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells

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12 December 2020

Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells

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12 December 2020

Irradiation Induces WAF1 Expression through a p53-independent Pathway in KG-1 Cells

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12 December 2020

AU-rich elements: characterization and importance in mRNA degradation

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12 December 2020

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

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12 December 2020

p21 is necessary for the p53-mediated G1 arrest in human cancer cells

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12 December 2020

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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12 December 2020

Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues

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12 December 2020

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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12 December 2020

P53 and its implication in apoptosis (review).

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12 December 2020

Principles of CDK regulation

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12 December 2020

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

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12 December 2020

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

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12 December 2020

Role of p21Waf1/Cip1/Sdi1 in cell death and DNA repair as studied using a tetracycline-inducible system in p53-deficient cells

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12 December 2020

p53-dependent elevation of p21Waf1 expression by UV light is mediated through mRNA stabilization and involves a vanadate-sensitive regulatory system

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12 December 2020

The regulation of cyclin-dependent kinase inhibitors (CKIs).

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12 December 2020

High levels of constitutive WAF1/Cip1 protein are associated with chemoresistance in acute myelogenous leukemia

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12 December 2020

Identifiers

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10440238%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

PubMed publication ID

10440238

1 reference