Diabetic macular edema: new concepts in patho-physiology and treatment (Q33713517)

28 July 2017

Diabetic macular edema: new concepts in patho-physiology and treatment (English)

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28 July 2017

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diabetic macular edema

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Xinyuan Zhang

1

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28 July 2017

Huan Zeng

2

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28 July 2017

Shian Bao

3

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28 July 2017

Ningli Wang

4

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28 July 2017

Mark C Gillies

5

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28 July 2017

14 May 2014

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28 July 2017

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28 July 2017

4

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28 July 2017

27

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https://scigraph.springernature.com/pub.10.1186/2045-3701-4-27

28 July 2017

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Classification of diabetic retinopathy and diabetic macular edema

14 July 2018

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VEGF but not PlGF disturbs the barrier of retinal endothelial cells

14 July 2018

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Glucocorticoid induction of occludin expression and endothelial barrier requires transcription factor p54 NONO

14 July 2018

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14 July 2018

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Subthreshold diode micropulse laser photocoagulation (SDM) as invisible retinal phototherapy for diabetic macular edema: a review

14 July 2018

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Global prevalence and major risk factors of diabetic retinopathy

14 July 2018

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14 July 2018

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Randomized clinical trial evaluating mETDRS versus normal or high-density micropulse photocoagulation for diabetic macular edema

14 July 2018

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Effect of prior intensive therapy in type 1 diabetes on 10-year progression of retinopathy in the DCCT/EDIC: comparison of adults and adolescents

14 July 2018

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Subthreshold micropulse diode laser photocoagulation for diabetic macular edema in Japanese patients

14 July 2018

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Vascular endothelial growth factor-A: a multifunctional molecular player in diabetic retinopathy

14 July 2018

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14 July 2018

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The Wisconsin Epidemiologic Study of Diabetic Retinopathy XXIII: the twenty-five-year incidence of macular edema in persons with type 1 diabetes

14 July 2018

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Association of vitreous inflammatory factors with diabetic macular edema

14 July 2018

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A randomized trial comparing intravitreal triamcinolone acetonide and focal/grid photocoagulation for diabetic macular edema

14 July 2018

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Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease

14 July 2018

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Effects of advanced glycation end products-inductor glyoxal and hydrogen peroxide as oxidative stress factors on rat retinal organ cultures and neuroprotection by UK-14,304.

14 July 2018

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Aldose reductase inhibitor fidarestat counteracts diabetes-associated cataract formation, retinal oxidative-nitrosative stress, glial activation, and apoptosis.

14 July 2018

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Protein kinase C-delta mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathway

14 July 2018

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Immunological mechanisms in the pathogenesis of diabetic retinopathy

14 July 2018

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PKCbetaII/HuR/VEGF: A new molecular cascade in retinal pericytes for the regulation of VEGF gene expression

14 July 2018

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Intravitreal triamcinolone acetonide inhibits breakdown of the blood-retinal barrier through differential regulation of VEGF-A and its receptors in early diabetic rat retinas

14 July 2018

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The status of diabetic retinopathy and diabetic macular edema in patients with type 2 diabetes: a survey from Beixinjing District of Shanghai city in China

14 July 2018

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VEGF in biological control.

14 July 2018

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Inducible nitric oxide synthase isoform is a key mediator of leukostasis and blood-retinal barrier breakdown in diabetic retinopathy

14 July 2018

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Management of diabetic retinopathy: a systematic review

14 July 2018

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Leukostasis and pigment epithelium-derived factor in rat models of diabetic retinopathy

14 July 2018

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The role of protein kinase C activation and the vascular complications of diabetes

14 July 2018

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The role of junctional adhesion molecules in vascular inflammation

14 July 2018

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TNF-alpha is critical for ischemia-induced leukostasis, but not retinal neovascularization nor VEGF-induced leakage

14 July 2018

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Study of claudin function by RNA interference

14 July 2018

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Junctional Adhesion Molecules (JAMs) are differentially expressed in fibroblasts and co-localize with ZO-1 to adherens-like junctions

14 July 2018

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Claudins in occluding junctions of humans and flies

14 July 2018

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The role of VEGF receptors in angiogenesis; complex partnerships

14 July 2018

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Glucocorticoid regulation of endothelial cell tight junction gene expression: novel treatments for diabetic retinopathy

14 July 2018

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Occludin: structure, function and regulation

14 July 2018

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Roles of the receptor for advanced glycation endproducts in diabetes-induced vascular injury

14 July 2018

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Evolution of retinal laser therapy: minimum intensity photocoagulation (MIP). Can the laser heal the retina without harming it?

14 July 2018

1 reference

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Diabetic macular edema: classification, medical and laser therapy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046142

The blood-retinal barriers system. Basic concepts and clinical evaluation.

14 July 2018

1 reference

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[The influence of spontaneous posterior vitreous detachment in resolution of diabetic macular edema in NIDDM].

14 July 2018

1 reference

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Upstream stimulatory factor (USF) proteins induce human TGF-beta1 gene activation via the glucose-response element-1013/-1002 in mesangial cells: up-regulation of USF activity by the hexosamine biosynthetic pathway

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046142

Junctional adhesion molecules (JAMs): more molecules with dual functions?

14 July 2018

1 reference

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The biology of VEGF and its receptors

14 July 2018

1 reference

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Signalling to and from tight junctions

14 July 2018

1 reference

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Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046142

14 July 2018

Tight junction proteins

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Diabetic vascular dysfunction: links to glucose-induced reductive stress and VEGF.

14 July 2018

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The hexosamine pathway regulates the plasminogen activator inhibitor-1 gene promoter and Sp1 transcriptional activation through protein kinase C-beta I and -delta

14 July 2018

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Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo

14 July 2018

1 reference

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Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046142

Characterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046142

Differential expression of neuropilin-1 and neuropilin-2 in arteries and veins

14 July 2018

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Excessive hexosamines block the neuroprotective effect of insulin and induce apoptosis in retinal neurons

14 July 2018

1 reference

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Vascular endothelial growth factor receptors in the regulation of angiogenesis and lymphangiogenesis

14 July 2018

1 reference

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Complex phenotype of mice lacking occludin, a component of tight junction strands.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046142

PKC-beta inhibitor (LY333531) attenuates leukocyte entrapment in retinal microcirculation of diabetic rats

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046142

Mechanisms of fluid accumulation in retinal edema

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046142

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

14 July 2018

1 reference

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The National Diabetic Retinopathy Laser Treatment Audit. III. Clinical outcomes

14 July 2018

1 reference

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Complications of retinal laser therapy and their prevention

14 July 2018

1 reference

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The biology of vascular endothelial growth factor

14 July 2018

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Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions

14 July 2018

1 reference

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Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid

14 July 2018

1 reference

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Endoneurial blood flow and oxygen tension in the sciatic nerves of rats with experimental diabetic neuropathy.

14 July 2018

1 reference

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Aldose reductase localization in human retinal mural cells

14 July 2018

1 reference

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Vitrectomy: a pars plana approach

14 July 2018

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Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

14 July 2018

1 reference

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Purification and NH2-terminal amino acid sequence of guinea pig tumor-secreted vascular permeability factor.

14 July 2018

1 reference

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The blood-retinal barriers

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046142

Prevalence and associated factors of diabetic retinopathy. The Beijing Eye Study 2006.

14 July 2018

1 reference

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A prospective study of serum lipids and risk of diabetic macular edema in type 1 diabetes

21 January 2018

1 reference

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Diabetic retinopathy is associated with a switch in splicing from anti- to pro-angiogenic isoforms of vascular endothelial growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-4-27

Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants

21 January 2018

1 reference

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Intravitreal injection of corticosteroid attenuates leukostasis and vascular leakage in experimental diabetic retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-4-27

VEGF164Is Proinflammatory in the Diabetic Retina

21 January 2018

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https://api.crossref.org/works/10.1186%2F2045-3701-4-27

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-4-27

VEGF activation of protein kinase C stimulates occludin phosphorylation and contributes to endothelial permeability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-4-27

Curcumin prevents diabetic cardiomyopathy in streptozotocin-induced diabetic rats: possible involvement of PKC-MAPK signaling pathway.

21 January 2018

1 reference

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Advanced glycation end products depress function of endothelial progenitor cells via p38 and ERK 1/2 mitogen-activated protein kinase pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-4-27

AGEs mediated expression and secretion of TNF alpha in rat retinal microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-4-27

Advanced glycation end products induce death of retinal neurons via activation of nitric oxide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-4-27

Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-4-27

A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-4-27

A selective aldose reductase inhibitor of a new structural class prevents or reverses early retinal abnormalities in experimental diabetic retinopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-4-27

Activation of the hexosamine pathway causes oxidative stress and abnormal embryo gene expression: involvement in diabetic teratogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-4-27

Neurovascular dysfunction in diabetic rats. Potential contribution of autoxidation and free radicals examined using transition metal chelating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-4-27

MTHFR gene polymorphism is susceptible to diabetic retinopathy but not to diabetic nephropathy in Japanese type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-4-27

Aldose reductase deficiency prevents diabetes-induced blood-retinal barrier breakdown, apoptosis, and glial reactivation in the retina of db/db mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-4-27

High-mobility group box-1 protein activates inflammatory signaling pathway components and disrupts retinal vascular-barrier in the diabetic retina.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046142

Prevalence of diabetic retinopathy in rural China: the Handan Eye Study

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046142

Polymorphism of the endothelial nitric oxide synthase gene is associated with diabetic retinopathy in a cohort of West Africans

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046142

Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046142

VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma

30 October 2018

1 reference

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Studies on the permeability of the blood-retinal barrier. IV. Junctional complexes of the retinal vessels and their role in the permeability of the blood-retinal barrier

30 October 2018

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12 December 2020

Proteomic analysis of vitreous from diabetic macular edema

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12 December 2020

A new concept for vitreous surgery. I. Instrumentation

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12 December 2020

Photocoagulation treatment of proliferative diabetic retinopathy. Clinical application of Diabetic Retinopathy Study (DRS) findings, DRS Report Number 8. The Diabetic Retinopathy Study Research Group

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12 December 2020

EFFECT OF HISTAMINE ON THE PERMEABILITY OF THE OCULAR VESSELS

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12 December 2020

Identification of multiple claudins in the rat epididymis

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12 December 2020

During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium

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12 December 2020

Photocoagulation for diabetic macular edema. Early Treatment Diabetic Retinopathy Study report number 1. Early Treatment Diabetic Retinopathy Study research group

1 reference

12 December 2020

The role of the vitreous in diabetic macular edema

1 reference

12 December 2020

Intravitreal tissue plasminogen activator to treat refractory diabetic macular edema by induction of posterior vitreous detachment

1 reference

12 December 2020

The Wisconsin epidemiologic study of diabetic retinopathy. XI. The incidence of macular edema

1 reference

12 December 2020

TGF-beta1 and TSC-22 gene polymorphisms and susceptibility to microvascular complications in type 2 diabetes

1 reference

12 December 2020

Inhibition of diabetic leukostasis and blood-retinal barrier breakdown with a soluble form of a receptor for advanced glycation end products

1 reference

12 December 2020

Vascular endothelial growth factor induces rapid phosphorylation of tight junction proteins occludin and zonula occluden 1. A potential mechanism for vascular permeability in diabetic retinopathy and tumors

1 reference

12 December 2020

Effect of high glucose on permeability of retinal capillary endothelium in vitro

1 reference

12 December 2020

Early photocoagulation for diabetic retinopathy. ETDRS report number 9. Early Treatment Diabetic Retinopathy Study Research Group

1 reference

12 December 2020

Prevention of diabetes-induced abnormal retinal blood flow by treatment with d-alpha-tocopherol

1 reference

12 December 2020

Identifiers

DOI

10.1186/2045-3701-4-27

1 reference

Dimensions Publication ID

28 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/2045-3701-4-27

release_v3dxs25nmrcunls7dcm5fmoaqi

9 September 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/v3dxs25nmrcunls7dcm5fmoaqi

24 November 2022

mapped directly with Wikidata item

PMCID

4046142

1 reference

28 July 2017

1 reference