Immunological mechanisms in the pathogenesis of diabetic retinopathy (Q37109989)

18 August 2017

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title

Immunological mechanisms in the pathogenesis of diabetic retinopathy (English)

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18 August 2017

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Anthony P Adamis

1

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PubMed ID

18340447

18 August 2017

Adrienne J Berman

series ordinal

2

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18 August 2017

14 March 2008

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Seminars in Immunopathology

18 August 2017

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18 August 2017

30

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18 August 2017

65-84

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18 August 2017

2

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https://scigraph.springernature.com/pub.10.1007/s00281-008-0111-x

18 August 2017

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Regression of neovascular age-related macular degeneration following infliximab therapy

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Angiotensin II and vascular endothelial growth factor in the vitreous fluid of patients with proliferative diabetic retinopathy

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Neuronal and microglial response in the retina of streptozotocin-induced diabetic rats

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Platelet aggregation and coagulation in the pathogenesis of diabetic retinopathy in rats

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Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor beta-1.

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Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy

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12 December 2020

Macrophage depletion inhibits experimental choroidal neovascularization

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12 December 2020

Expression of acute-phase response proteins in retinal Müller cells in diabetes

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Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration

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12 December 2020

Vitreous levels of angiopoietin 2 and vascular endothelial growth factor in patients with proliferative diabetic retinopathy

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12 December 2020

Macrophages in proliferative vitreoretinopathy and proliferative diabetic retinopathy: differentiation of subpopulations

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12 December 2020

An association in non-insulin-dependent diabetes mellitus subjects between susceptibility to retinopathy and tumor necrosis factor polymorphism

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12 December 2020

Vitreous levels of interleukin-6 and vascular endothelial growth factor are related to diabetic macular edema

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12 December 2020

The kallikrein-kinin and the renin-angiotensin systems have a multilayered interaction

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12 December 2020

Expression of CD18 on the neutrophils of patients with diabetic retinopathy.

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12 December 2020

A central role for inflammation in the pathogenesis of diabetic retinopathy

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12 December 2020

Regression of sight-threatening macular edema in type 2 diabetes following treatment with the anti-tumor necrosis factor monoclonal antibody infliximab

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12 December 2020

Aspirin at low-intermediate concentrations protects retinal vessels in experimental diabetic retinopathy through non-platelet-mediated effects

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12 December 2020

Platelets accumulate in the diabetic retinal vasculature following endothelial death and suppress blood-retinal barrier breakdown

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12 December 2020

Tumor necrosis factor-alpha in diabetic plasma increases the activity of core 2 GlcNAc-T and adherence of human leukocytes to retinal endothelial cells: significance of core 2 GlcNAc-T in diabetic retinopathy

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Targeting angiogenesis, the underlying disorder in neovascular age-related macular degeneration

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Activated monocytes and granulocytes, capillary nonperfusion, and neovascularization in diabetic retinopathy

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12 December 2020

Distribution of TNF alpha and its reactive vascular adhesion molecules in fibrovascular membranes of proliferative diabetic retinopathy

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12 December 2020

Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo

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12 December 2020

The critical role of ocular-infiltrating macrophages in the development of choroidal neovascularization

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12 December 2020

Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures

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12 December 2020

The effect of long-term treatment with sulindac on the progression of diabetic retinopathy

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12 December 2020

Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions

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12 December 2020

Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy

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12 December 2020

Human mesangial cells and peripheral blood mononuclear cells produce vascular permeability factor

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12 December 2020

Diabetic retinopathy: seeing beyond glucose-induced microvascular disease.

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12 December 2020

A prize catch for diabetic retinopathy.

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A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

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12 December 2020

Diabetic retinopathy: more than meets the eye.

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12 December 2020

Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy

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12 December 2020

Relationship between vascular endothelial growth factor and interleukin-6 in diabetic retinopathy

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12 December 2020

A phase II randomized double-masked trial of pegaptanib, an anti-vascular endothelial growth factor aptamer, for diabetic macular edema

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12 December 2020

Valsartan but not Atenolol Improves Vascular Pathology in Diabetic Ren-2 Rat Retina

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12 December 2020

Molecular understanding of hyperglycemia's adverse effects for diabetic complications

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12 December 2020

Cell surface morphology identifies microglia as a distinct class of mononuclear phagocyte

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12 December 2020

Increased prevalence of microthromboses in retinal capillaries of diabetic individuals

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12 December 2020

Intravitreal injection of bevacizumab (Avastin) as adjunctive treatment of proliferative diabetic retinopathy

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12 December 2020

VEGF164Is Proinflammatory in the Diabetic Retina

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12 December 2020

CD4-CD8 and CD28 expression in T cells infiltrating the vitreous fluid in patients with proliferative diabetic retinopathy: a flow cytometric analysis.

1 reference

12 December 2020

Development of ranibizumab, an anti-vascular endothelial growth factor antigen binding fragment, as therapy for neovascular age-related macular degeneration

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12 December 2020

Targeted deletion of B2-kinin receptors protects against the development of diabetic nephropathy

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12 December 2020

Pharmacological inhibition of diabetic retinopathy: aminoguanidine and aspirin

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12 December 2020

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1

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12 December 2020

Neutrophil-derived cytokines: potential therapeutic targets in inflammation.

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12 December 2020

A prospective trial of infliximab therapy for refractory uveitis: preliminary safety and efficacy outcomes.

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12 December 2020

Effects of aspirin treatment on diabetic retinopathy. ETDRS report number 8. Early Treatment Diabetic Retinopathy Study Research Group

1 reference

12 December 2020

Platelet expression of tumour necrosis factor-alpha (TNF-alpha), TNF receptors and intercellular adhesion molecule-1 (ICAM-1) in patients with proliferative diabetic retinopathy

1 reference

12 December 2020

Vascular endothelial growth factor and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives.

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12 December 2020

Leukocyte-mediated endothelial cell injury and death in the diabetic retina

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12 December 2020

Inflammatory cytokines in vitreous fluid and serum of patients with diabetic vitreoretinopathy

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12 December 2020

Tumour necrosis factor alpha as a therapeutic target for immune-mediated inflammatory diseases

1 reference

12 December 2020

Vitreous levels of vascular endothelial growth factor and intercellular adhesion molecule 1 are related to diabetic macular edema

1 reference

12 December 2020

Insulin-like growth factor-I plays a pathogenetic role in diabetic retinopathy

1 reference

12 December 2020

Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-alpha

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12 December 2020

VEGF-initiated blood-retinal barrier breakdown in early diabetes.

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12 December 2020

Inhibitors of ocular neovascularization: promises and potential problems.

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12 December 2020

Effector function of diabetogenic CD4 Th1 T cell clones: a central role for TNF-alpha

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12 December 2020

The renin-angiotensin and the kallikrein-kinin systems

1 reference

12 December 2020

Proteomic analysis of human vitreous fluid by fluorescence-based difference gel electrophoresis (DIGE): a new strategy for identifying potential candidates in the pathogenesis of proliferative diabetic retinopathy

1 reference

12 December 2020

Effect of aspirin alone and aspirin plus dipyridamole in early diabetic retinopathy. A multicenter randomized controlled clinical trial. The DAMAD Study Group

1 reference

12 December 2020

Immunocytochemical localization of vascular endothelial growth factor in neurons and glial cells of human retina

1 reference

12 December 2020

Suppression of Fas-FasL-induced endothelial cell apoptosis prevents diabetic blood-retinal barrier breakdown in a model of streptozotocin-induced diabetes

1 reference

12 December 2020

Regression of iris neovascularization after intravitreal injection of bevacizumab in patients with proliferative diabetic retinopathy

1 reference

12 December 2020

Vascular endothelial growth factor (VEGF)-induced retinal vascular permeability is mediated by intercellular adhesion molecule-1 (ICAM-1).

1 reference

12 December 2020

Vascular endothelial growth factor and the potential therapeutic use of pegaptanib (macugen) in diabetic retinopathy

1 reference

12 December 2020

Sequential induction of angiogenic growth factors by TNF-alpha in choroidal endothelial cells

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12 December 2020

Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy

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12 December 2020

Expression of vascular endothelial growth factor by human eosinophils: upregulation by granulocyte macrophage colony-stimulating factor and interleukin-5.

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12 December 2020

Macrophage and retinal pigment epithelium expression of angiogenic cytokines in choroidal neovascularization.

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12 December 2020

Advanced glycation end products increase retinal vascular endothelial growth factor expression

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12 December 2020

Effects of a selective bradykinin B1 receptor antagonist on increased plasma extravasation in streptozotocin-induced diabetic rats: distinct vasculopathic profile of major key organs

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12 December 2020

Ischemic vascular damage can be repaired by healthy, but not diabetic, endothelial progenitor cells

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12 December 2020

Vitreous levels of vascular endothelial growth factor and stromal-derived factor 1 in patients with diabetic retinopathy and cystoid macular edema before and after intraocular injection of triamcinolone

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12 December 2020

Catalogue of soluble proteins in human vitreous humor by one-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis and electrospray ionization mass spectrometry including seven angiogenesis-regulating factors

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12 December 2020

Effects of angiotensin-converting enzyme inhibitors and beta-adrenergic blockers on retinal vascular endothelial growth factor expression in rat diabetic retinopathy

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12 December 2020

Intravitreous injections of vascular endothelial growth factor produce retinal ischemia and microangiopathy in an adult primate

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12 December 2020

Nitric oxide cytoskeletal-induced alterations reverse the endothelial progenitor cell migratory defect associated with diabetes

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12 December 2020

In vivo retinal gene expression in early diabetes.

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12 December 2020

Vascular endothelial growth factor reduced and connective tissue growth factor induced by triamcinolone in ARPE19 cells under oxidative stress.

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12 December 2020

VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization.

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12 December 2020

Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation

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12 December 2020

Peripheral blood T lymphocytes and lymphocytes infiltrating human cancers express vascular endothelial growth factor: a potential role for T cells in angiogenesis.

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12 December 2020

Intracellular pool of vascular endothelial growth factor in human neutrophils

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12 December 2020

A novel inflammatory pathway involved in leukocyte recruitment: role for the kinin B1 receptor and the chemokine CXCL5

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12 December 2020

Triamcinolone acetonide protects the rat retina from STZ-induced acute inflammation and early vascular leakage.

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12 December 2020

Macrophage depletion diminishes lesion size and severity in experimental choroidal neovascularization

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12 December 2020

Vascular endothelial growth factor is a critical stimulus for diabetic macular edema

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12 December 2020

Leukocytes mediate retinal vascular remodeling during development and vaso-obliteration in disease

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12 December 2020

Hereditary angioedema

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12 December 2020

Changes in retinal neovascularization after pegaptanib (Macugen) therapy in diabetic individuals

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12 December 2020

A pilot study of multiple intravitreal injections of ranibizumab in patients with center-involving clinically significant diabetic macular edema

1 reference

12 December 2020

Erythropoietin is expressed in the human retina and it is highly elevated in the vitreous fluid of patients with diabetic macular edema

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12 December 2020

Suppression of diabetes-induced retinal inflammation by blocking the angiotensin II type 1 receptor or its downstream nuclear factor-kappaB pathway

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12 December 2020

Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo

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12 December 2020

Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy

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12 December 2020

Serum inflammatory markers in diabetic retinopathy

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12 December 2020

Clinical pharmacokinetics and use of infliximab

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12 December 2020

Neutrophils are associated with capillary closure in spontaneously diabetic monkey retinas

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12 December 2020

Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression

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12 December 2020

Enhanced expression of intracellular adhesion molecule-1 and P-selectin in the diabetic human retina and choroid.

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12 December 2020

Relationship of polymorphonuclear leukocytes to capillary dropout in the human diabetic choroid.

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12 December 2020

Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy

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12 December 2020

Integrin-mediated neutrophil adhesion and retinal leukostasis in diabetes

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12 December 2020

Tumor necrosis factor-alpha regulates expression of vascular endothelial growth factor receptor-2 and of its co-receptor neuropilin-1 in human vascular endothelial cells.

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12 December 2020

Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis in a primate model.

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12 December 2020

Angiotensin II and vascular endothelial growth factor in the vitreous fluid of patients with diabetic macular edema and other retinal disorders

1 reference

12 December 2020

Glial reactivity, an early feature of diabetic retinopathy.

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12 December 2020

Single periocular injection of celecoxib-PLGA microparticles inhibits diabetes-induced elevations in retinal PGE2, VEGF, and vascular leakage.

1 reference

12 December 2020

Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy

1 reference

12 December 2020

Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo.

1 reference

12 December 2020

10.1007/S00281-008-0111-X

Identifiers

DOI

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18 August 2017

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PubMed ID

18340447