Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity (Q33724394)

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17 March 2020

title

Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity (English)

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17 March 2020

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Prabhakara R Nagareddy

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17 March 2020

Michael J Kraakman

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Seth L Masters

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17 March 2020

Ryan W. Grant

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17 March 2020

Ahmed Abdel-Latif

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Sung Hee Choi

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Edward A Fisher

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Andrew Murphy

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Susan S Smyth

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17 March 2020

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Karin E Bornfeldt

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17 March 2020

author name string

Roslynn A Stirzaker

4

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17 March 2020

Darren J Gorman

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Dragana Dragoljevic

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Eun Shil Hong

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Judith Korner

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17 March 2020

Vishwa Deep Dixit

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17 March 2020

Alan R Tall

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17 March 2020

Ira J Goldberg

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17 March 2020

publication date

1 May 2014

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17 March 2020

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17 March 2020

volume

19

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17 March 2020

issue

5

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17 March 2020

page(s)

821-835

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Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation

17 March 2020

cites work

1 reference

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Local proliferation dominates lesional macrophage accumulation in atherosclerosis

21 June 2018

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Hyperglycemia promotes myelopoiesis and impairs the resolution of atherosclerosis

21 June 2018

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Expanded granulocyte/monocyte compartment in myeloid-specific triple FoxO knockout increases oxidative stress and accelerates atherosclerosis in mice

21 June 2018

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MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice

21 June 2018

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21 June 2018

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The cytokine release inhibitory drug CRID3 targets ASC oligomerisation in the NLRP3 and AIM2 inflammasomes

21 June 2018

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Increased macrophage migration into adipose tissue in obese mice

21 June 2018

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CD14 controls the LPS-induced endocytosis of Toll-like receptor 4

21 June 2018

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Diabetes impairs hematopoietic stem cell mobilization by altering niche function

21 June 2018

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ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

21 June 2018

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Clodronate liposomes improve metabolic profile and reduce visceral adipose macrophage content in diet-induced obese mice

21 June 2018

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CD14dimCD16+ and CD14+CD16+ monocytes in obesity and during weight loss: relationships with fat mass and subclinical atherosclerosis

21 June 2018

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Increased levels of calprotectin in obesity are related to macrophage content: impact on inflammation and effect of weight loss

21 June 2018

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Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation

21 June 2018

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Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression

21 June 2018

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Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

21 June 2018

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The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

21 June 2018

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IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ

21 June 2018

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21 June 2018

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Endogenous ligands of TLR2 and TLR4: agonists or assistants?

21 June 2018

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21 June 2018

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IL-1R type I-dependent hemopoietic stem cell proliferation is necessary for inflammatory granulopoiesis and reactive neutrophilia

21 June 2018

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Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals

21 June 2018

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S100A8 and S100A9 mediate endotoxin-induced cardiomyocyte dysfunction via the receptor for advanced glycation end products

21 June 2018

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TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

21 June 2018

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JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity

21 June 2018

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A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways

21 June 2018

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Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

21 June 2018

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Metabolic endotoxemia initiates obesity and insulin resistance

21 June 2018

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21 June 2018

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Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

21 June 2018

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21 June 2018

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

21 June 2018

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21 June 2018

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Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance

21 June 2018

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Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment

21 June 2018

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Adipose tissue transplantation protects ob/ob mice from obesity, normalizes insulin sensitivity and restores fertility

21 June 2018

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Adipose tissue, inflammation, and cardiovascular disease

21 June 2018

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Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade

21 June 2018

1 reference

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IKK-beta links inflammation to obesity-induced insulin resistance

21 June 2018

1 reference

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Obesity is associated with macrophage accumulation in adipose tissue

21 June 2018

1 reference

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Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice

21 June 2018

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 June 2018

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Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies

21 June 2018

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Biologic basis for interleukin-1 in disease

21 June 2018

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Prognostic importance of the white blood cell count for coronary, cancer, and all-cause mortality

21 June 2018

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Proliferating macrophages populate established atherosclerotic lesions.

21 June 2018

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Proliferating macrophages prevail in atherosclerosis

30 October 2018

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ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation

30 October 2018

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WBC count and the risk of cancer mortality in a national sample of U.S. adults: results from the Second National Health and Nutrition Examination Survey mortality study.

30 October 2018

1 reference

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Elevated white blood cell count in subjects with impaired glucose tolerance

30 October 2018

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Leukocyte count, erythrocyte sedimentation rate, and diabetes incidence in a national sample of US adults

30 October 2018

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Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes?

30 October 2018

1 reference

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Systemic inflammation in childhood obesity: circulating inflammatory mediators and activated CD14++ monocytes

30 October 2018

1 reference

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The Inflammasome in Atherosclerosis and Type 2 Diabetes

30 October 2018

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12 December 2020

Monocyte heterogeneity in obesity and subclinical atherosclerosis

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12 December 2020

Comparison of numbers of circulating blood monocytes in men grouped by body mass index (<25, 25 to <30, > or =30)

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12 December 2020

Markers of inflammation and prediction of diabetes mellitus in adults (Atherosclerosis Risk in Communities study): a cohort study

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12 December 2020

10.1016/J.CMET.2014.03.029

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24807222%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24807222%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

PubMed publication ID

24807222

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24807222%20AND%20SRC:MED&resulttype=core&format=json