Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRbeta/B-RAF. (Q33732613)

29 July 2017

title

Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRbeta/B-RAF. (English)

1 reference

29 July 2017

Sudarshan Anand

9

0 references

Peter K. Vogt

object named as

Peter K Vogt

17

0 references

Robert M Hoffman

14

object named as

Robert M Hoffman

1 reference

29 July 2017

Eric A Murphy

1

1 reference

29 July 2017

David J Shields

2

1 reference

29 July 2017

Konstantin Stoletov

3

1 reference

29 July 2017

Elena Dneprovskaia

4

1 reference

29 July 2017

Michele McElroy

5

1 reference

29 July 2017

Joshua I Greenberg

6

1 reference

29 July 2017

Jeff Lindquist

7

1 reference

29 July 2017

Lisette M Acevedo

8

1 reference

29 July 2017

Bharat Kumar Majeti

10

1 reference

29 July 2017

Igor Tsigelny

11

1 reference

29 July 2017

Adrian Saldanha

12

1 reference

29 July 2017

Breda Walsh

13

1 reference

29 July 2017

Michael Bouvet

15

1 reference

29 July 2017

Richard L Klemke

16

1 reference

29 July 2017

Lee Arnold

18

1 reference

29 July 2017

Wolfgang Wrasidlo

19

1 reference

29 July 2017

David A Cheresh

20

1 reference

29 July 2017

language of work or name

English

0 references

publication date

12 February 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

1 reference

29 July 2017

volume

107

1 reference

29 July 2017

issue

9

1 reference

29 July 2017

page(s)

4299-4304

1 reference

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

29 July 2017

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1 reference

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Tumor microenvironment and angiogenesis

21 June 2018

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21 June 2018

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Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting

21 June 2018

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21 June 2018

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Angiogenic factors FGF2 and PDGF-BB synergistically promote murine tumor neovascularization and metastasis.

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization

21 June 2018

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21 June 2018

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Nestin-linked green fluorescent protein transgenic nude mouse for imaging human tumor angiogenesis

21 June 2018

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

21 June 2018

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A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells

21 June 2018

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Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

21 June 2018

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Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors

21 June 2018

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Intravitreous anti-raf-1 kinase antisense oligonucleotide as an angioinhibitory agent in porcine preretinal neovascularization

21 June 2018

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21 June 2018

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Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells.

21 June 2018

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In vivo imaging of embryonic vascular development using transgenic zebrafish

21 June 2018

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The role of the microenvironment and intercellular cross-talk in tumor angiogenesis

21 June 2018

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Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

21 June 2018

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Immortal activated human hepatic stellate cells generated by ectopic telomerase expression

21 June 2018

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Real-time optical imaging of primary tumor growth and multiple metastatic events in a pancreatic cancer orthotopic model.

21 June 2018

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Discovery of a novel Raf kinase inhibitor

21 June 2018

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Active Ras induces heterodimerization of cRaf and BRaf

21 June 2018

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Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

21 June 2018

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Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

21 June 2018

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Activated Ras displaces 14-3-3 protein from the amino terminus of c-Raf-1

21 June 2018

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21 June 2018

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21 June 2018

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21 January 2018

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Yaf2 inhibits caspase 8-mediated apoptosis and regulates cell survival during zebrafish embryogenesis

21 January 2018

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Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability

21 January 2018

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Dual-color imaging of nascent blood vessels vascularizing pancreatic cancer in an orthotopic model demonstrates antiangiogenesis efficacy of gemcitabine

21 January 2018

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Selective antimetastatic activity of cytosine analog CS-682 in a red fluorescent protein orthotopic model of pancreatic cancer

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840076

In vitro three dimensional collagen matrix models of endothelial lumen formation during vasculogenesis and angiogenesis

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20154271

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of Raf in vascular protection from distinct apoptotic stimuli

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20154271

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Development of a high metastatic orthotopic model of human renal cell carcinoma in nude mice: benefits of fragment implantation compared to cell-suspension injection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20154271

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0909299107

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference