Induction of ectopic Myc target gene JAG2 augments hypoxic growth and tumorigenesis in a human B-cell model (Q33734728)

29 July 2017

title

Induction of ectopic Myc target gene JAG2 augments hypoxic growth and tumorigenesis in a human B-cell model (English)

1 reference

29 July 2017

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Jason T Yustein

1

1 reference

29 July 2017

Yen-Chun Liu

2

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29 July 2017

Ping Gao

3

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29 July 2017

Chunfa Jie

4

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29 July 2017

Anne Le

5

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29 July 2017

Milena Vuica-Ross

6

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29 July 2017

Wee Joo Chng

7

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29 July 2017

Charles G Eberhart

8

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29 July 2017

P Leif Bergsagel

9

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29 July 2017

Chi V Dang

10

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29 July 2017

language of work or name

English

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publication date

2 February 2010

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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29 July 2017

volume

107

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29 July 2017

issue

8

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29 July 2017

page(s)

3534-3539

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Heterozygosity for hypoxia inducible factor 1alpha decreases the incidence of thymic lymphomas in a p53 mutant mouse model

29 July 2017

cites work

1 reference

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Frequent expression of multiple myeloma 1/interferon regulatory factor 4 in Burkitt lymphoma.

21 June 2018

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Distinct thresholds govern Myc's biological output in vivo

21 June 2018

1 reference

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Reflecting on 25 years with MYC.

21 June 2018

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21 June 2018

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Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia

21 June 2018

1 reference

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Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840500

Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1

21 June 2018

1 reference

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HIF-dependent antitumorigenic effect of antioxidants in vivo

21 June 2018

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Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor

21 June 2018

1 reference

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21 June 2018

Notch signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840500

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

21 June 2018

1 reference

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Cell target genes of Epstein-Barr virus transcription factor EBNA-2: induction of the p55alpha regulatory subunit of PI3-kinase and its role in survival of EREB2.5 cells

21 June 2018

1 reference

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c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

21 June 2018

1 reference

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MYC levels govern hematopoietic tumor type and latency in transgenic mice

21 June 2018

1 reference

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c-myc overexpression causes anaplasia in medulloblastoma

21 June 2018

1 reference

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Hypoxia requires notch signaling to maintain the undifferentiated cell state

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840500

Overexpression of the NOTCH ligand JAG2 in malignant plasma cells from multiple myeloma patients and cell lines.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840500

Viral interactions with the Notch pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840500

HES and HERP families: multiple effectors of the Notch signaling pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840500

Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840500

Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840500

Cell cycle activation by c-myc in a burkitt lymphoma model cell line.

21 June 2018

1 reference

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Reversible tumorigenesis by MYC in hematopoietic lineages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840500

The proto-oncogene c-myc is a direct target gene of Epstein-Barr virus nuclear antigen 2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840500

Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840500

Pathogenesis of Burkitt lymphoma: expression of an activated c-myc oncogene causes the tumorigenic conversion of EBV-infected human B lymphoblasts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840500

AID-dependent activation of a MYC transgene induces multiple myeloma in a conditional mouse model of post-germinal center malignancies.

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0901230107

A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840500

Notch activity synergizes with B-cell-receptor and CD40 signaling to enhance B-cell activation

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20133585

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Gamma-secretase inhibitors suppress the growth of leukemia and lymphoma cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20133585

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0901230107

1 reference

29 July 2017

0 references

1 reference

29 July 2017

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