Four generations of transition-state analogues for human purine nucleoside phosphorylase. (Q33740145)

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19 January 2020

title

Four generations of transition-state analogues for human purine nucleoside phosphorylase (English)

1 reference

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Purine nucleoside phosphorylase

19 January 2020

main subject

1 reference

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Gary B. Evans

5

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19 January 2020

Keith Clinch

6

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19 January 2020

7

Steven C Almo

1 reference

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19 January 2020

8

Vern L Schramm

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19 January 2020

4

Peter C Tyler

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19 January 2020

author name string

Meng-Chiao Ho

1

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19 January 2020

Wuxian Shi

2

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19 January 2020

Agnes Rinaldo-Matthis

3

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19 January 2020

language of work or name

English

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publication date

8 March 2010

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

19 January 2020

published in

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19 January 2020

volume

107

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19 January 2020

issue

11

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19 January 2020

page(s)

4805-4812

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Enzymatic transition states and dynamic motion in barrier crossing

19 January 2020

cites work

1 reference

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Altered enthalpy-entropy compensation in picomolar transition state analogues of human purine nucleoside phosphorylase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841916

Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase

21 June 2018

1 reference

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Atomic detail of chemical transformation at the transition state of an enzymatic reaction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841916

Enzymatic transition state theory and transition state analogue design

21 June 2018

1 reference

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Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase †

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841916

Purine nucleoside analogs as immunosuppressive and antineoplastic agents: mechanism of action and clinical activity

21 June 2018

1 reference

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Novel purine nucleoside analogues for T-cell-lineage acute lymphoblastic leukaemia and lymphoma

21 June 2018

1 reference

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Enzymatic transition states: thermodynamics, dynamics and analogue design

21 June 2018

1 reference

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Coot: model-building tools for molecular graphics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841916

Structural basis for inhibition of human PNP by immucillin-H

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841916

A graphical user interface to the CCP4 program suite

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841916

Implementation of molecular replacement in AMoRe

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841916

Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841916

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 June 2018

1 reference

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One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase

21 June 2018

1 reference

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Purine nucleoside phosphorylase. 1. Structure-function studies

21 June 2018

1 reference

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Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity

21 June 2018

1 reference

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Transition state analysis for human and Plasmodium falciparum purine nucleoside phosphorylases.

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913439107

Purine nucleoside phosphorylase. Catalytic mechanism and transition-state analysis of the arsenolysis reaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913439107

Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913439107

Insight into catalytically relevant correlated motions in human purine nucleoside phosphorylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913439107

Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases

21 January 2018

1 reference

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Activating the phosphate nucleophile at the catalytic site of purine nucleoside phosphorylase: a vibrational spectroscopic study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913439107

Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: convergent synthesis of the aza-C-nucleoside immucillins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913439107

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913439107

MOLREP: an Automated Program for Molecular Replacement

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913439107

Synthesis of a Transition State Analogue Inhibitor of Purine Nucleoside Phosphorylase via the Mannich Reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913439107

21 January 2018

Identifiers

DOI

10.1073/PNAS.0913439107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20212140%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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1 reference

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19 January 2020

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