Insulin enhances glucose-stimulated insulin secretion in healthy humans (Q33740824)

29 July 2017

Insulin enhances glucose-stimulated insulin secretion in healthy humans (English)

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29 July 2017

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10

C Ronald Kahn

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29 July 2017

6

Darko Stefanovski

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29 July 2017

Clara Bouche

1

1 reference

29 July 2017

Ximena Lopez

2

1 reference

29 July 2017

Amy Fleischman

3

1 reference

29 July 2017

Aaron M Cypess

4

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29 July 2017

Sheila O'Shea

5

1 reference

29 July 2017

Richard N Bergman

7

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29 July 2017

Eduard Rogatsky

8

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29 July 2017

Daniel T Stein

9

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29 July 2017

Rohit N Kulkarni

11

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29 July 2017

Allison B Goldfine

12

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29 July 2017

language of work or name

English

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publication date

22 February 2010

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

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29 July 2017

107

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29 July 2017

4770-4775

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29 July 2017

10

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Insulin signaling in alpha cells modulates glucagon secretion in vivo

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Growth factor control of pancreatic islet regeneration and function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Acute effects of insulin on beta-cells from transplantable human islets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Chronic hyperglycemia impairs insulin secretion by affecting insulin receptor expression, splicing, and signaling in RIN β‐cell line and human islets of Langerhans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Diabetes mellitus and genetically programmed defects in beta-cell function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

The Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Insulin-stimulated insulin secretion in single pancreatic beta cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Disruption of IRS-2 causes type 2 diabetes in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Novel, non-crinophagic, degradation of connecting peptide in transformed pancreatic beta cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Insulin secretion in diabetes mellitus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

C-peptide and insulin secretion. Relationship between peripheral concentrations of C-peptide and insulin and their secretion rates in the dog.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Prevention of the Glucose Intolerance of Thiazide Diuretics by Maintenance of Body Potassium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Control of insulin secretion by catecholamines, stress, and the sympathetic nervous system.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Beta adrenergic-mediated vasodilator response to insulin in the human forearm.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Direct hemodynamic effect of insulin in the isolated perfused kidney

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

IRS-3 inhibits IRS-2-mediated signaling in pancreatic beta-cells

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Gene expression heterogeneity in human islet endocrine cells in vitro: the insulin signalling cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Identification of insulin signaling elements in human beta-cells: autocrine regulation of insulin gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Feedback inhibition of insulin secretion by insulin: relation to the hyperinsulinemia of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Failure of insulin infusion during euglycemia to influence endogenous basal insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Lilly lecture 2003: the struggle for mastery in insulin action: from triumvirate to republic

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta -cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Acute diabetes moderates trafficking of cardiac lipoprotein lipase through p38 mitogen-activated protein kinase-dependent actin cytoskeleton organization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Glucose-dependent promotion of insulin release from mouse pancreatic islets by the insulin-mimetic compound L-783,281.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Insulin secretory function is impaired in isolated human islets carrying the Gly(972)-->Arg IRS-1 polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Renal extraction of insulin and C-peptide in man before and after a glucose meal

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Reduced β-cell mass and altered glucose sensing impair insulin-secretory function in βIRKO mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842068

30 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000002107

Glucose-stimulated insulin biosynthesis depends on insulin-stimulated insulin gene transcription

21 January 2018

1 reference

12 December 2020

Renal metabolism of C-peptide in man

1 reference

12 December 2020

Des-(27-31)C-peptide. A novel secretory product of the rat pancreatic beta cell produced by truncation of proinsulin connecting peptide in secretory granules

1 reference

12 December 2020

PROMOTION OF INSULIN SECRETION BY GLUCAGON

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1000002107

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29 July 2017

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29 July 2017

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