Activated protein C promotes breast cancer cell migration through interactions with EPCR and PAR-1. (Q33749766)

29 July 2017

Activated protein C promotes breast cancer cell migration through interactions with EPCR and PAR-1. (English)

1 reference

29 July 2017

1 reference

1 reference

1 reference

Lea M Beaulieu

1

1 reference

PubMed ID

17254565

29 July 2017

Frank C Church

series ordinal

2

1 reference

PubMed ID

17254565

29 July 2017

language of work or name

English

0 references

publication date

14 December 2006

1 reference

Experimental Cell Research

29 July 2017

1 reference

29 July 2017

313

1 reference

29 July 2017

4

1 reference

29 July 2017

677-687

1 reference

Urokinase induces basophil chemotaxis through a urokinase receptor epitope that is an endogenous ligand for formyl peptide receptor-like 1 and -like 2.

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Expression of active plasminogen activator inhibitor-1 reduces cell migration and invasion in breast and gynecological cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Activated protein C inhibits bronchial hyperresponsiveness and Th2 cytokine expression in mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Activated protein C signals through the thrombin receptor PAR1 in endothelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Inhibition of staurosporine-induced apoptosis of endothelial cells by activated protein C requires protease-activated receptor-1 and endothelial cell protein C receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Protein C pathway in sepsis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Expression and regulation of CD97 in colorectal carcinoma cell lines and tumor tissues

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Signaling from protease-activated receptor-1 inhibits migration and invasion of breast cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

A cell-based model of hemostasis

21 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

21 June 2018

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2006.11.019

Thrombin-thrombomodulin activation of protein C facilitates the activation of progelatinase A.

7 January 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Efficacy and safety of recombinant human activated protein C for severe sepsis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Histone deacetylase inhibitors decrease proliferation and modulate cell cycle gene expression in normal mammary epithelial cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Identification of the protein C/activated protein C binding sites on the endothelial cell protein C receptor. Implications for a novel mode of ligand recognition by a major histocompatibility complex class 1-type receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Reconstitution of the human endothelial cell protein C receptor with thrombomodulin in phosphatidylcholine vesicles enhances protein C activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Role of thrombin receptor in breast cancer invasiveness

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Identification of functional endothelial protein C receptor in human plasma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Regulation of human colonic cell line proliferation and phenotype by sodium butyrate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Urokinase receptor is a multifunctional protein: influence of receptor occupancy on macrophage gene expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Regulation of activated protein C by a new protein. A possible function for bovine protein S.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Characterization of a cDNA coding for human protein C

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Proteolytic processing of the 72,000-Da type IV collagenase by urokinase plasminogen activator

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

The role of plasminogen activators in the regulation of connective tissue metalloproteinases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

A new vitamin K-dependent protein. A phospholipid-binding zymogen of a serine esterase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Proteolytic activation of protein C from bovine plasma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Anticoagulant properties of bovine plasma protein C following activation by thrombin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Endothelial protein C receptor-dependent inhibition of migration of human lymphocytes by protein C involves epidermal growth factor receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Activated protein C prevents inflammation yet stimulates angiogenesis to promote cutaneous wound healing.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

PAR1 cleavage and signaling in response to activated protein C and thrombin.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Activated protein C stimulates proliferation, migration and wound closure, inhibits apoptosis and upregulates MMP-2 activity in cultured human keratinocytes.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Activated protein C induces endothelial cell proliferation by mitogen-activated protein kinase activation in vitro and angiogenesis in vivo.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Sodium butyrate inhibits angiogenesis of human intestinal microvascular endothelial cells through COX‐2 inhibition

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Endothelial protein C receptor-dependent inhibition of human eosinophil chemotaxis by protein C.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Synergistic down-regulation of urokinase plasminogen activator receptor and matrix metalloproteinase-9 in SNB19 glioblastoma cells efficiently inhibits glioma cell invasion, angiogenesis, and tumor growth

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Recombinant murine-activated protein C is neuroprotective in a murine ischemic stroke model.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Plasminogen activator inhibitor-1 and -3 increase cell adhesion and motility of MDA-MB-435 breast cancer cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Activated protein C prevents endotoxin-induced hypotension in rats by inhibiting excessive production of nitric oxide

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Anti-inflammatory, antithrombotic, and neuroprotective effects of activated protein C in a murine model of focal ischemic stroke.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

Binding of latent matrix metalloproteinase 9 to fibrin: activation via a plasmin-dependent pathway.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055951

The endothelial cell protein C receptor. Cell surface expression and direct ligand binding by the soluble receptor

30 October 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2006.11.019

The inhibition of blood coagulation by activated protein C through the selective inactivation of activated factor V

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2006.11.019

Human protein C: inactivation of factors V and VIII in plasma by the activated molecule

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2006.11.019

7 January 2021

The Protein C Pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2006.11.019

Activated protein C directly activates human endothelial gelatinase A

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2006.11.019

Contrasting effects of plasminogen activators, urokinase receptor, and LDL receptor-related protein on smooth muscle cell migration and invasion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2006.11.019

Regulation of activated protein C by protein S. The role of phospholipid in factor Va inactivation

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17254565

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of activated protein C in facilitating basement membrane invasion by tumor cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17254565

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The endothelial cell protein C receptor aids in host defense against Escherichia coli sepsis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17254565

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.YEXCR.2006.11.019

1 reference

29 July 2017

1 reference

29 July 2017

1 reference

PubMed ID

17254565