Mutant p53 exhibits trivial effects on mitochondrial functions which can be reactivated by ellipticine in lymphoma cells (Q33755827)

29 July 2017

title

Mutant p53 exhibits trivial effects on mitochondrial functions which can be reactivated by ellipticine in lymphoma cells (English)

1 reference

29 July 2017

Fei Wang

1

1 reference

29 July 2017

Jianfeng Liu

2

1 reference

29 July 2017

Delira Robbins

3

1 reference

29 July 2017

Kerri Morris

4

1 reference

29 July 2017

Amos Sit

5

1 reference

29 July 2017

Yong-Yu Liu

6

1 reference

29 July 2017

Yunfeng Zhao

7

1 reference

29 July 2017

publication date

1 March 2011

1 reference

29 July 2017

1 reference

29 July 2017

volume

16

1 reference

29 July 2017

issue

3

1 reference

29 July 2017

page(s)

301-310

1 reference

Resistance of mitochondrial p53 to dominant inhibition

29 July 2017

cites work

1 reference

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CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice

14 July 2018

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p53 alterations in human cancer: more questions than answers.

14 July 2018

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p53 regulates mitochondrial respiration

14 July 2018

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Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma

14 July 2018

1 reference

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Betulinic acid, a natural cytotoxic agent, fails to trigger apoptosis in human Burkitt's lymphoma-derived B-cell lines

14 July 2018

1 reference

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p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N2-oxide

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation

14 July 2018

1 reference

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Mitochondrial p53 levels parallel total p53 levels independent of stress response in human colorectal carcinoma and glioblastoma cells

14 July 2018

1 reference

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Small molecules that reactivate mutant p53.

14 July 2018

1 reference

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P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

Delayed expression of apoptosis in human lymphoma cells undergoing low-dose taxol-induced mitotic stress.

14 July 2018

1 reference

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p53 has a direct apoptogenic role at the mitochondria

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

"Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally

14 July 2018

1 reference

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p53 mutant mice that display early ageing-associated phenotypes

14 July 2018

1 reference

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Nuclear and mitochondrial apoptotic pathways of p53.

14 July 2018

1 reference

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Direct influence of the p53 tumor suppressor on mitochondrial biogenesis and function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

14 July 2018

1 reference

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The role of p53-target genes in human cancer

14 July 2018

1 reference

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p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

Activation of p53 in MDM2-overexpressing cells through phosphorylation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

Reactivation of mutant p53: a new strategy for cancer therapy.

14 July 2018

1 reference

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Correcting temperature-sensitive protein folding defects

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

p53, the cellular gatekeeper for growth and division

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

Interference by doxorubicin with DNA unwinding in MCF-7 breast tumor cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

Database of p53 gene somatic mutations in human tumors and cell lines

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

Inhibition of p53 Protein Phosphorylation by 9‐Hydroxyellipticine: A Possible Anticancer Mechanism

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

Stereochemistry of Intercalation: Interaction of Daunomycin with DNA

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

Evidence for a common mechanism of action for antitumor and antibacterial agents that inhibit type II DNA topoisomerases.

14 July 2018

1 reference

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p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

Mutant p53 detected in a majority of Burkitt lymphoma cell lines by monoclonal antibody PAb240.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

p53 mutations in Raji cells: characterization and localization relative to other Burkitt's lymphomas

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078632

Controversial Chinese gene-therapy drug entering unfamiliar territory

14 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-010-0559-8

Tamoxifen protects against acute tumor necrosis factor alpha-induced cardiac injury via improving mitochondrial functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-010-0559-8

Rescue of mutant p53 transcription function by ellipticine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-010-0559-8

Research into fish diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-010-0559-8

Casein kinase 2 inhibition decreases hypoxia-inducible factor-1 activity under hypoxia through elevated p53 protein level

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21107702

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mutant p53 mediated induction of cell cycle arrest and apoptosis at G1 phase by 9-hydroxyellipticine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21107702

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S10495-010-0559-8

1 reference

29 July 2017

1 reference

29 July 2017

1 reference