TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4(+) T cell fate and interact with Runx3 to silence Cd4 in CD8(+) T cells (Q33779910)

29 July 2017

TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4(+) T cell fate and interact with Runx3 to silence Cd4 in CD8(+) T cells (English)

1 reference

29 July 2017

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Hai-Hui Xue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

author name string

Farrah C Steinke

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Shuyang Yu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Xinyuan Zhou

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Bing He

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Wenjing Yang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Bo Zhou

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Hiroshi Kawamoto

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Jun Zhu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

language of work or name

English

0 references

publication date

18 May 2014

1 reference

29 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

page(s)

646-656

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/ni.2897

3 June 2020

exact match

0 references

cites work

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Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Transcriptional and epigenetic regulation of CD4/CD8 lineage choice.

4 July 2018

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MEME-ChIP: motif analysis of large DNA datasets

4 July 2018

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T-cell lineage determination

4 July 2018

1 reference

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Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells.

4 July 2018

1 reference

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CD4-CD8 lineage differentiation: Thpok-ing into the nucleus

4 July 2018

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mTOR regulates memory CD8 T-cell differentiation

4 July 2018

1 reference

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RUNX proteins in transcription factor networks that regulate T-cell lineage choice

4 July 2018

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Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice

4 July 2018

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Model-based analysis of ChIP-Seq (MACS)

4 July 2018

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ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage

4 July 2018

1 reference

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Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells

4 July 2018

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RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis

4 July 2018

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WNT signalling in the immune system: WNT is spreading its wings

4 July 2018

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Development of all CD4 T lineages requires nuclear factor TOX

4 July 2018

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Launching the T-cell-lineage developmental programme

4 July 2018

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4 July 2018

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c-Myb regulates lineage choice in developing thymocytes via its target gene Gata3.

4 July 2018

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Groucho/transducin-like Enhancer-of-split (TLE)-dependent and -independent transcriptional regulation by Runx3.

4 July 2018

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The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment.

4 July 2018

1 reference

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IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: impact on thymocyte development.

4 July 2018

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GA binding protein regulates interleukin 7 receptor alpha-chain gene expression in T cells

4 July 2018

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Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis

4 July 2018

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4 July 2018

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Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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A novel class II MHC molecule with unusual tissue distribution

4 July 2018

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Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

4 July 2018

1 reference

CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus.

21 January 2018

1 reference

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

21 January 2018

1 reference

The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy.

21 January 2018

1 reference

TCF-1 mediates repression of Notch pathway in T lineage-committed early thymocytes

21 January 2018

1 reference

Cooperating pre-T-cell receptor and TCF-1-dependent signals ensure thymocyte survival.

21 January 2018

1 reference

Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate.

21 January 2018

1 reference

Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation.

21 January 2018

1 reference

Antagonistic interactions between Ikaros and the chromatin remodeler Mi-2beta determine silencer activity and Cd4 gene expression

21 January 2018

1 reference

Decision by committee: new light on the CD4/CD8-lineage choice

21 January 2018

1 reference

An HMG-box-containing T-cell factor required for thymocyte differentiation.

21 January 2018

1 reference

Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24836425

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Overexpression of the Runx3 transcription factor increases the proportion of mature thymocytes of the CD8 single-positive lineage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24836425

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24836425

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.2897

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

3 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24836425%20AND%20SRC:MED&resulttype=core&format=json