Rapamycin regulates endothelial cell migration through regulation of the cyclin-dependent kinase inhibitor p27Kip1. (Q33782496)

29 July 2017

title

Rapamycin regulates endothelial cell migration through regulation of the cyclin-dependent kinase inhibitor p27Kip1. (English)

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29 July 2017

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Stephanie C Moss

1

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29 July 2017

Daniel J Lightell

2

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29 July 2017

Steven O Marx

3

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29 July 2017

Andrew R Marks

4

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29 July 2017

T Cooper Woods

5

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29 July 2017

language of work or name

English

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publication date

22 January 2010

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29 July 2017

number of pages

7

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Journal of Biological Chemistry

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published in

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29 July 2017

volume

285

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29 July 2017

issue

16

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29 July 2017

page(s)

11991-11997

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describes a project that uses

29 July 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2852937/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Tyrosine phosphatase SHP-2 is a regulator of p27(Kip1) tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

4 July 2018

The two TORCs and Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

A pooled analysis of data comparing sirolimus-eluting stents with bare-metal stents

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Stent thrombosis in randomized clinical trials of drug-eluting stents

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Antiangiogenic potential of the Mammalian target of rapamycin inhibitor temsirolimus

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Upstream and downstream of mTOR

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

p27Kip1 modulates cell migration through the regulation of RhoA activation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Cell migration: integrating signals from front to back

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Coordinate control of proliferation and migration by the p27Kip1/cyclin-dependent kinase/retinoblastoma pathway in vascular smooth muscle cells and fibroblasts.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Deregulated degradation of the cdk inhibitor p27 and malignant transformation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

p27KIP1, an inhibitor of cyclin-dependent kinases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Rapamycin resistance tied to defective regulation of p27Kip1.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Analysis of 1-year clinical outcomes in the SIRIUS trial: a randomized trial of a sirolimus-eluting stent versus a standard stent in patients at high risk for coronary restenosis

4 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.066621

Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.066621

Analysis of 14 trials comparing sirolimus-eluting stents with bare-metal stents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.066621

mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.066621

Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.066621

Role for p27(Kip1) in Vascular Smooth Muscle Cell Migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.066621

A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.066621

Cell cycle protein expression in vascular smooth muscle cells in vitro and in vivo is regulated through phosphatidylinositol 3-kinase and mammalian target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.066621

Rho-kinase and myosin II activities are required for cell type and environment specific migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.066621

Overexpression of p27(Kip1) by doxycycline-regulated adenoviral vectors inhibits endothelial cell proliferation and migration and impairs angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.066621

mTORC2 regulates PGE2-mediated endothelial cell survival and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.066621

Effect of p27 deficiency and rapamycin on intimal hyperplasia: in vivo and in vitro studies using a p27 knockout mouse model

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852937

Distinct regulation of mitogen-activated protein kinases and p27Kip1 in smooth muscle cells from different vascular beds. A potential role in establishing regional phenotypic variance

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20097763

12 December 2020

inferred from PubMed ID database lookup

A simple method of isolating mouse aortic endothelial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20097763

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M109.066621

1 reference

29 July 2017

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29 July 2017

1 reference