A metabolomics approach using juvenile cystic mice to identify urinary biomarkers and altered pathways in polycystic kidney disease (Q33784024)

29 July 2017

A metabolomics approach using juvenile cystic mice to identify urinary biomarkers and altered pathways in polycystic kidney disease (English)

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polycystic kidney disease

29 July 2017

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5

Oliver Fiehn

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29 July 2017

Sandra L Taylor

1

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29 July 2017

Sheila Ganti

2

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29 July 2017

Nikolay O Bukanov

3

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29 July 2017

Arlene Chapman

4

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29 July 2017

Michael Osier

6

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29 July 2017

Kyoungmi Kim

7

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29 July 2017

Robert H Weiss

8

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29 July 2017

3 February 2010

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American Journal of Physiology - Renal Physiology

29 July 2017

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29 July 2017

298

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29 July 2017

4

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29 July 2017

F909-22

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KEGG for representation and analysis of molecular networks involving diseases and drugs

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Radiation metabolomics. 3. Biomarker discovery in the urine of gamma-irradiated rats using a simplified metabolomics protocol of gas chromatography-mass spectrometry combined with random forests machine learning algorithm.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Grade-dependent proteomics characterization of kidney cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Metabolomics of neural progenitor cells: a novel approach to biomarker discovery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Urine metabolomics analysis for kidney cancer detection and biomarker discovery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

S-adenosylhomocysteine hydrolase downregulation contributes to tumorigenesis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Quality control for plant metabolomics: reporting MSI-compliant studies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Metabolomics in biomarker discovery: future uses for cancer prevention

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

SetupX--a public study design database for metabolomic projects

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Polycystic kidney diseases: from molecular discoveries to targeted therapeutic strategies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Determinants of renal volume in autosomal-dominant polycystic kidney disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Clinical proof-of-concept trial to assess the therapeutic effect of sirolimus in patients with autosomal dominant polycystic kidney disease: SUISSE ADPKD study

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

p21 is decreased in polycystic kidney disease and leads to increased epithelial cell cycle progression: roscovitine augments p21 levels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

WilcoxCV: an R package for fast variable selection in cross-validation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

A comprehensive urinary metabolomic approach for identifying kidney cancerr

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Polycystic kidney disease: genes, proteins, animal models, disease mechanisms and therapeutic opportunities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Pathway analysis of kidney cancer using proteomics and metabolic profiling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Peroxisome biogenesis disorders

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

PLS dimension reduction for classification with microarray data

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

A simple quantitative assay for urinary adenosine using column-switching high-performance liquid chromatography

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Nek8 mutation causes overexpression of galectin-1, sorcin, and vimentin and accumulation of the major urinary protein in renal cysts of jck mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Calcium restriction allows cAMP activation of the B-Raf/ERK pathway, switching cells to a cAMP-dependent growth-stimulated phenotype

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Metabolomics--a new exciting field within the "omics" sciences

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Partial least squares proportional hazard regression for application to DNA microarray survival data

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

The fundamental importance of human galactose metabolism: lessons from genetics and biochemistry

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

New insights into polycystic kidney disease and its treatment

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Evaluation of ultrasonographic diagnostic criteria for autosomal dominant polycystic kidney disease 1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Evidence for a substrate cycle between AMP and adenosine in isolated hepatocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Hyperuricemia, gout, and autosomal dominant polycystic kidney disease.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853321

Approaches to testing new treatments in autosomal dominant polycystic kidney disease: insights from the CRISP and HALT-PKD studies

28 July 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00722.2009

Chronic renal allograft dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00722.2009

Allantoin in human plasma, serum, and nasal-lining fluids as a biomarker of oxidative stress: avoiding artifacts and establishing real in vivo concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00722.2009

Regulation of renal adenosine excretion in humans--role of sodium and fluid homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00722.2009

Simultaneous determination of uric acid metabolites allantoin, 6-aminouracil, and triuret in human urine using liquid chromatography-mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00722.2009

Identification of a unique urinary biomarker profile in patients with autosomal dominant polycystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00722.2009

Autosomal dominant polycystic kidney disease: role of the renin-angiotensin system in raised blood pressure in progression of renal and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00722.2009

Application of metabolomics to cardiovascular biomarker and pathway discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00722.2009

Serum and urinary biomarker signatures for rapid preclinical in vivo assessment of CDK inhibition as a therapeutic approach for PKD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00722.2009

Using the gene ontology for microarray data mining: a comparison of methods and application to age effects in human prefrontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00722.2009

Metabolomics takes its place as latest up-and-coming "omic" science.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00722.2009

Development of polycystic kidney disease in juvenile cystic kidney mice: insights into pathogenesis, ciliary abnormalities, and common features with human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00722.2009

Mitotic activation of Akt signalling pathway in Han:SPRD rats with polycystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00722.2009

Comprehensive molecular diagnostics in autosomal dominant polycystic kidney disease

21 January 2018

1 reference

12 December 2020

Magnetic resonance imaging evaluation of hepatic cysts in early autosomal-dominant polycystic kidney disease: the Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease cohort

1 reference

12 December 2020

Earlier diagnosis of autosomal dominant polycystic kidney disease: importance of family history and implications for cardiovascular and renal complications

1 reference

12 December 2020

Unified ultrasonographic diagnostic criteria for polycystic kidney disease

1 reference

12 December 2020

Strategies to inhibit cyst formation in ADPKD

1 reference

12 December 2020

Renal epithelial fluid secretion and cyst growth: the role of cyclic AMP

1 reference

12 December 2020

10.1152/AJPRENAL.00722.2009

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DOI

1 reference

29 July 2017

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29 July 2017

1 reference