Double-stranded RNA-independent dimerization of interferon-induced protein kinase PKR and inhibition of dimerization by the cellular P58IPK inhibitor (Q33786424)

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English	Double-stranded RNA-independent dimerization of interferon-induced protein kinase PKR and inhibition of dimerization by the cellular P58IPK inhibitor	scientific article

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Double-stranded RNA-independent dimerization of interferon-induced protein kinase PKR and inhibition of dimerization by the cellular P58IPK inhibitor (English)

1 reference

Europe PubMed Central

29 July 2017

author name string

S L Tan

1

1 reference

Europe PubMed Central

29 July 2017

M J Gale

2

1 reference

Europe PubMed Central

29 July 2017

M G Katze

3

1 reference

Europe PubMed Central

29 July 2017

language of work or name

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publication date

1 May 1998

1 reference

Europe PubMed Central

29 July 2017

Molecular and Cellular Biology

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Europe PubMed Central

29 July 2017

18

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Europe PubMed Central

29 July 2017

5

1 reference

Europe PubMed Central

29 July 2017

2431-2443

1 reference

Europe PubMed Central

29 July 2017

Biochemical and genetic evidence for complex formation between the influenza A virus NS1 protein and the interferon-induced PKR protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

Regulation of interferon-induced protein kinase PKR: modulation of P58IPK inhibitory function by a novel protein, P52rIPK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein

1 reference

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4 July 2018

The Tat protein of human immunodeficiency virus type 1 is a substrate and inhibitor of the interferon-induced, virally activated protein kinase, PKR

1 reference

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4 July 2018

Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore.

1 reference

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4 July 2018

Form and function in protein dephosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

Autophosphorylation sites participate in the activation of the double-stranded-RNA-activated protein kinase PKR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

PIN: an associated protein inhibitor of neuronal nitric oxide synthase

1 reference

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Identification and characterization of two novel tetratricopeptide repeat-containing genes

1 reference

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Receptor signaling: dimerization and beyond

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4 July 2018

Specific mutations near the amino terminus of double-stranded RNA-dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization properties

1 reference

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Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization.

1 reference

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4 July 2018

Interaction of the interferon-induced PKR protein kinase with inhibitory proteins P58IPK and vaccinia virus K3L is mediated by unique domains: implications for kinase regulation

1 reference

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The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain

1 reference

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Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

1 reference

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4 July 2018

Conservation, evolution, and specificity in cellular control by protein phosphorylation

1 reference

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4 July 2018

Molecular glue: kinase anchoring and scaffold proteins

1 reference

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4 July 2018

Active and inactive protein kinases: structural basis for regulation

1 reference

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4 July 2018

Double-stranded (ds) RNA binding and not dimerization correlates with the activation of the dsRNA-dependent protein kinase (PKR).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

The P58 cellular inhibitor complexes with the interferon-induced, double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

Mechanism of interferon action. Biochemical and genetic evidence for the intermolecular association of the RNA-dependent protein kinase PKR from human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

On target with a new mechanism for the regulation of protein phosphorylation

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Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

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Linking an easily detectable phenotype to the folding of a common structural motif. Selection of rare turn mutations that prevent the folding of Rop.

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4 July 2018

Translational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinase

1 reference

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4 July 2018

The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans

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4 July 2018

Activation of the double-stranded RNA (dsRNA)-activated human protein kinase in vivo in the absence of its dsRNA binding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

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Sequence of the human glycogen-associated regulatory subunit of type 1 protein phosphatase and analysis of its coding region and mRNA level in muscle from patients with NIDDM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

Cellular inhibitors of the interferon-induced, dsRNA-activated protein kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

1 reference

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4 July 2018

Organization of the double-stranded RNA-activated protein kinase DAI and virus-associated VA RNAI in adenovirus-2-infected HeLa cells.

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4 July 2018

Vitamin D receptor contains multiple dimerization interfaces that are functionally different

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4 July 2018

Cdk inhibitors: on the threshold of checkpoints and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

Dimerization of cell surface receptors in signal transduction

1 reference

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4 July 2018

Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains

1 reference

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4 July 2018

Nuclear localization of the interferon-inducible protein kinase PKR in human cells and transfected mouse cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

Mechanism of interferon action: evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

1 reference

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4 July 2018

Molecular mechanisms responsible for malignant transformation by regulatory and catalytic domain variants of the interferon-induced enzyme RNA-dependent protein kinase

1 reference

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4 July 2018

Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo

1 reference

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4 July 2018

The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

Mechanism of interferon action: characterization of the intermolecular autophosphorylation of PKR, the interferon-inducible, RNA-dependent protein kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation

1 reference

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4 July 2018

Regulation of the interferon-induced PKR: can viruses cope?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

The 58-kilodalton inhibitor of the interferon-induced double-stranded RNA-activated protein kinase is a tetratricopeptide repeat protein with oncogenic properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

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The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

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Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAI

1 reference

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High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier

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4 July 2018

Identification of a 90-kDa polypeptide which associates with adenovirus VA RNAI and is phosphorylated by the double-stranded RNA-dependent protein kinase.

1 reference

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A novel genetic system to detect protein-protein interactions

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A type 1 phosphoprotein phosphatase active with phosphorylated Mr = 68,000 initiation factor 2 kinase

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4 July 2018

Basic local alignment search tool

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1 reference

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Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

1 reference

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4 July 2018

Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

Modified subcellular localization of interferon-induced p68 kinase during encephalomyocarditis virus infection

1 reference

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4 July 2018

Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells

1 reference

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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

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4 July 2018

Intrasteric regulation of protein kinases and phosphatases

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4 July 2018

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

Characterization and regulation of the 58,000-dalton cellular inhibitor of the interferon-induced, dsRNA-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

Cytosolic double-stranded RNA-dependent protein kinase is likely a dimer of partially phosphorylated Mr = 66,000 subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110623

4 July 2018

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4 July 2018

Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2

1 reference

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4 July 2018

Mechanism of interferon action: autoregulation of RNA-dependent P1/eIF-2 alpha protein kinase (PKR) expression in transfected mammalian cells

1 reference

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4 July 2018

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1 reference

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30 October 2018

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30 October 2018

Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor

1 reference

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30 October 2018

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30 October 2018

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30 October 2018

Repressor fusions as a tool to study protein-protein interactions

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of protein kinase CK2: dimerization of the human beta-subunit

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https://pubmed.ncbi.nlm.nih.gov/9566864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional expression and characterization of the interferon-induced double-stranded RNA activated P68 protein kinase from Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solution structure of the cAMP-dependent protein kinase catalytic subunit and its contraction upon binding the protein kinase inhibitor peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-affinity binding and localization of the cyclic GMP-dependent protein kinase with the intermediate filament protein vimentin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 58-kDa cellular inhibitor of the double stranded RNA-dependent protein kinase requires the tetratricopeptide repeat 6 and DnaJ motifs to stimulate protein synthesis in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ribosome targeting of PKR is mediated by two double-stranded RNA-binding domains and facilitates in vivo phosphorylation of eukaryotic initiation factor-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct dimerization domains provide antagonist pathways for thyroid hormone receptor action

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.18.5.2431

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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