Conserved modular domains team up to latch-open active protein kinase Cα (Q33793028)

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17 March 2020

title

Conserved modular domains team up to latch-open active protein kinase Cα (English)

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17 March 2020

4

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17 March 2020

John Tesmer

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17 March 2020

Margaret V Westfall

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17 March 2020

author name string

Carter J Swanson

1

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17 March 2020

Michael Ritt

2

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17 March 2020

William Wang

3

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17 March 2020

Arvind Narayan

5

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17 March 2020

Sivaraj Sivaramakrishnan

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17 March 2020

language of work or name

English

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publication date

30 April 2014

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Journal of Biological Chemistry

17 March 2020

published in

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17 March 2020

volume

289

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17 March 2020

issue

25

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17 March 2020

page(s)

17812-17829

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Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-α

17 March 2020

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Inhibition of protein kinase C catalytic activity by additional regions within the human protein kinase Calpha-regulatory domain lying outside of the pseudosubstrate sequence

4 July 2018

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Regulation of protein kinase C-related protein kinase 2 (PRK2) by an intermolecular PRK2-PRK2 interaction mediated by Its N-terminal domain

21 January 2018

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Kinetic mechanism of fully activated S6K1 protein kinase

21 January 2018

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Scanning mutagenesis studies reveal multiple distinct regions within the human protein kinase C alpha regulatory domain important for phorbol ester-dependent activation of the enzyme

21 January 2018

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PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity.

21 January 2018

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Molecular mechanism for the regulation of rho-kinase by dimerization and its inhibition by fasudil

21 January 2018

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Domain structure and phosphorylation of protein kinase C

21 January 2018

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12 December 2020

Protein kinase C contains a pseudosubstrate prototope in its regulatory domain

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12 December 2020

Phosphorylation of protein kinase C-alpha on serine 657 controls the accumulation of active enzyme and contributes to its phosphatase-resistant state

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12 December 2020

The last 10 amino acid residues beyond the hydrophobic motif are critical for the catalytic competence and function of protein kinase Calpha

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12 December 2020

Identifiers

DOI

10.1074/JBC.M113.534750

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24790081%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24790081%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

PubMed publication ID

24790081

1 reference