Metabolism and the leukemic stem cell. (Q33795007)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20368582%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

Metabolism and the leukemic stem cell (English)

1 reference

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30 January 2020

1 reference

1

1 reference

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30 January 2020

author name string

Ross L Levine

series ordinal

2

1 reference

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30 January 2020

language of work or name

English

0 references

publication date

5 April 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20368582%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

30 January 2020

published in

1 reference

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30 January 2020

volume

207

1 reference

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30 January 2020

issue

4

1 reference

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30 January 2020

page(s)

677-680

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Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia

30 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

Genetic analysis of transforming events that convert chronic myeloproliferative neoplasms to leukemias

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

The hematopoietic stem cell niche: low in oxygen but a nice place to be.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

Recurring mutations found by sequencing an acute myeloid leukemia genome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

IDH1 and IDH2 mutations in gliomas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

Potent antitumor activity of novel iron chelators derived from di-2-pyridylketone isonicotinoyl hydrazone involves fenton-derived free radical generation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

Multilineage embryonic hematopoiesis requires hypoxic ARNT activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856035

Distinct clinical and biologic characteristics in adult acute myeloid leukemia bearing the isocitrate dehydrogenase 1 mutation.

28 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100523

Taxing sugar-sweetened beverages

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100523

Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100523

Regulation of replicative senescence by NADP+ -dependent isocitrate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100523

Small interfering RNA-mediated silencing of mitochondrial NADP+-dependent isocitrate dehydrogenase enhances the sensitivity of HeLa cells toward tumor necrosis factor-alpha and anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100523

NMDA receptor activation and respiratory chain complex V inhibition contribute to neurodegeneration in d-2-hydroxyglutaric aciduria

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100523

D-2-hydroxyglutaric acid induces oxidative stress in cerebral cortex of young rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100523

An integrated genomic analysis of human glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100523

Survival of acute myeloid leukemia cells requires PI3 kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100523

HIF-1 is essential for multilineage hematopoiesis in the embryo

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20368582

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Somatic mutations of IDH1 and IDH2 in the leukemic transformation of myeloproliferative neoplasms

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20368582

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20100523

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20368582%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20368582%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

PubMed publication ID

20368582

1 reference