Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia (Q33795018)

29 July 2017

Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia (English)

1 reference

29 July 2017

1 reference

acute myeloid leukemia

1 reference

23

1 reference

29 July 2017

Isabelle Radford-Weiss

4

Isabelle Radford-Weiss

1 reference

29 July 2017

Jerome Naudin

3

0 references

Saurabh Agarwal

Saurabh Agarwal

8

0 references

Marc Benhamou

Marc Benhamou

18

0 references

Ivan C Moura

Ivan C Moura

22

0 references

Renato Monteiro

Renato C Monteiro

21

0 references

Hervé Dombret

19

Hervé Dombret

1 reference

29 July 2017

14

Danielle Canioni

1 reference

29 July 2017

Celine Callens

1

1 reference

29 July 2017

Séverine Coulon

2

1 reference

29 July 2017

Nicolas Boissel

5

1 reference

29 July 2017

Emmanuel Raffoux

6

1 reference

29 July 2017

Pamella Huey Mei Wang

7

1 reference

29 July 2017

Houda Tamouza

9

1 reference

29 July 2017

Etienne Paubelle

10

1 reference

29 July 2017

Vahid Asnafi

11

1 reference

29 July 2017

Jean-Antoine Ribeil

12

1 reference

29 July 2017

Philippe Dessen

13

1 reference

29 July 2017

Olivia Chandesris

15

1 reference

29 July 2017

Marie Therese Rubio

16

1 reference

29 July 2017

Carole Beaumont

17

1 reference

29 July 2017

Elizabeth Macintyre

20

1 reference

29 July 2017

language of work or name

English

0 references

publication date

5 April 2010

1 reference

Journal of Experimental Medicine

29 July 2017

1 reference

29 July 2017

207

1 reference

29 July 2017

731-750

1 reference

29 July 2017

4

1 reference

Vitamin D3-driven signals for myeloid cell differentiation--implications for differentiation therapy

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Proteomic and genetic approaches identify Syk as an AML target

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

High-dose daunorubicin in older patients with acute myeloid leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Objectives of iron chelation therapy in myelodysplastic syndromes: more than meets the eye?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Erlotinib and gefitinib for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a preclinical comparison

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Phospholipid scramblase 1 modulates a selected set of IgE receptor-mediated mast cell responses through LAT-dependent pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Acute promyelocytic leukemia: from highly fatal to highly curable

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Cooperating gene mutations in acute myeloid leukemia: a review of the literature.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Transcriptional control of granulocyte and monocyte development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Recent advances in adult T-cell leukemia therapy: focus on a new anti-transferrin receptor monoclonal antibody

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Progress in the treatment of acute myeloid leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Iron signaling and oxidant damage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Rewired ERK-JNK signaling pathways in melanoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Iron chelation and regulation of the cell cycle: 2 mechanisms of posttranscriptional regulation of the universal cyclin-dependent kinase inhibitor p21CIP1/WAF1 by iron depletion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Prevention of mantle lymphoma tumor establishment by routing transferrin receptor toward lysosomal compartments

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

The transferrin receptor part II: targeted delivery of therapeutic agents into cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

The JNK are important for development and survival of macrophages

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Genetics of myeloid malignancies: pathogenetic and clinical implications

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Quantitative single cell determination of ERK phosphorylation and regulation in relapsed and refractory primary acute myeloid leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

The oxidative environment and protein damage.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

The molecular basis of leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Potent antitumor activity of novel iron chelators derived from di-2-pyridylketone isonicotinoyl hydrazone involves fenton-derived free radical generation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Iron trafficking in the mitochondrion: novel pathways revealed by disease.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Iron chelators with high antiproliferative activity up-regulate the expression of a growth inhibitory and metastasis suppressor gene: a link between iron metabolism and proliferation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Retinoblastoma protein and CCAAT/enhancer-binding protein beta are required for 1,25-dihydroxyvitamin D3-induced monocytic differentiation of HL60 cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

1alpha, 25-dihydroxy-vitamin D3 alters Syk activation through FcgammaRII in monocytic THP-1 cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Genetics of myeloid leukemias

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Transcriptional regulation of granulocyte and monocyte development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

A review of fluorescence methods for assessing labile iron in cells and biological fluids

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Signal transduction by MAP kinases: regulation by phosphorylation-dependent switches

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Pathways of retinoic acid- or arsenic trioxide-induced PML/RARalpha catabolism, role of oncogene degradation in disease remission

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Identification of the transferrin receptor as a novel immunoglobulin (Ig)A1 receptor and its enhanced expression on mesangial cells in IgA nephropathy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

28 July 2018

Acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Hematopoietic growth factors signal through the formation of reactive oxygen species

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Human vitamin D receptor phosphorylation by casein kinase II at Ser-208 potentiates transcriptional activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

The effect of the iron(III) chelator, desferrioxamine, on iron and transferrin uptake by the human malignant melanoma cell

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

The relationship of erythropoietin and iron metabolism to red blood cell production in humans.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Transferrin receptors in human tissues: their distribution and possible clinical relevance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Structure and function of transferrin receptors and their relationship to cell growth.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Expression of the CD11/CD18, leukocyte adhesion molecule 1, and CD44 adhesion molecules during normal myeloid and erythroid differentiation in humans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Proposals for the Classification of the Acute Leukaemias French-American-British (FAB) Co-operative Group

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

1 alpha,25-dihydroxyvitamin D3 transrepresses retinoic acid transcriptional activity via vitamin D receptor in myeloid cells

28 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

Vitamin D signalling pathways in cancer: potential for anticancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

THE COMBINED USE OF MICROINCINERATION AND THE PRUSSIAN BLUE REACTION FOR A MORE SENSITIVE HISTOCHEMICAL DEMONSTRATION OF IRON

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

The vitamin D3/Hox-A10 pathway supports MafB function during the monocyte differentiation of human CD34+ hemopoietic progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

1alpha,25-dihydroxyvitamin D(3)-induced myeloid cell differentiation is regulated by a vitamin D receptor-phosphatidylinositol 3-kinase signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

Vitamin D(2) analog (Paricalcitol; Zemplar) for treatment of myelodysplastic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

Cellular response to oxidative stress: signaling for suicide and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

A neutralizing monoclonal antibody (mAb A24) directed against the transferrin receptor induces apoptosis of tumor T lymphocytes from ATL patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

Heterozygous PU.1 mutations are associated with acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

Iron overload adversely affects outcome of allogeneic hematopoietic cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

Cooperation of activating Ras/rtk signal transduction pathway mutations and inactivating myeloid differentiation gene mutations in M0 AML: a study of 45 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

Effect of 1,25(OH)2 Vitamin D3 analogs on differentiation induction and cytokine modulation in blasts from acute myeloid leukemia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

HOX-A10 regulates hematopoietic lineage commitment: evidence for a monocyte-specific transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

Methods for studying signal-dependent regulation of translation factor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

Differentiating agents + low-dose chemotherapy in the management of old/poor prognosis patients with acute myeloid leukemia or myelodysplastic syndrome

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

Induction of macrophage differentiation of human normal and leukemic myeloid stem cells by 1,25-dihydroxyvitamin D3 and its fluorinated analogues.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856037

A transcription factor party during blood cell differentiation

30 October 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091488

Jun N-terminal kinase pathway enhances signaling of monocytic differentiation of human leukemia cells induced by 1,25-dihydroxyvitamin D3

21 January 2018

1 reference

12 December 2020

Transferrin and transferrin receptors in carcinoma of the breast

1 reference

12 December 2020

Anti-transferrin receptor monoclonal antibody and toxin–antibody conjugates affect growth of human tumour cells

1 reference

12 December 2020

Transferrin-receptor interaction and iron uptake by reticulocytes of vertebrate animals--a comparative study

1 reference

12 December 2020

Retinoic acid and acute promyelocytic leukemia: a model of targetting treatment for human cancer

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20091488

1 reference

29 July 2017

1 reference

29 July 2017

1 reference