Ascidians: an invertebrate chordate model to study Alzheimer's disease pathogenesis (Q33798710)

29 July 2017

title

Ascidians: an invertebrate chordate model to study Alzheimer's disease pathogenesis (English)

1 reference

29 July 2017

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Michael J Virata

1

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29 July 2017

Robert W Zeller

series ordinal

2

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29 July 2017

publication date

2 March 2010

1 reference

Disease Models & Mechanisms

29 July 2017

published in

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29 July 2017

volume

3

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29 July 2017

issue

5-6

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29 July 2017

page(s)

377-385

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Forecasting the global burden of Alzheimer’s disease

29 July 2017

cites work

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4 July 2018

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4 July 2018

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Molecular and cellular mechanisms for Alzheimer's disease: understanding APP metabolism

4 July 2018

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4 July 2018

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Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

4 July 2018

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Development of swimming behaviour in the larva of the ascidian Ciona intestinalis

4 July 2018

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4 July 2018

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Tunicates and not cephalochordates are the closest living relatives of vertebrates

4 July 2018

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Transgenic C. elegans as a model in Alzheimer's research

4 July 2018

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4 July 2018

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Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation.

4 July 2018

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Intraneuronal Abeta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease.

4 July 2018

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Generation and use of transgenic ascidian embryos

4 July 2018

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4 July 2018

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Amyloid-beta precursor protein processing in neurodegeneration

4 July 2018

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The neurobiology of the ascidian tadpole larva: recent developments in an ancient chordate.

4 July 2018

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Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease

4 July 2018

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Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease

4 July 2018

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Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy.

4 July 2018

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4 July 2018

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

4 July 2018

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Direct evidence for the role of pigment cells in the brain of ascidian larvae by laser ablation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068634

Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model

4 July 2018

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

4 July 2018

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The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a review

4 July 2018

1 reference

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Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype

4 July 2018

1 reference

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Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide

4 July 2018

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Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans

4 July 2018

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The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

4 July 2018

1 reference

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The 717Val----Ile substitution in amyloid precursor protein is associated with familial Alzheimer's disease regardless of ethnic groups

4 July 2018

1 reference

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An improved thioflavine S method for staining neurofibrillary tangles and senile plaques in Alzheimer's disease

4 July 2018

1 reference

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A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

4 July 2018

1 reference

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Neurons of the ascidian larval nervous system in Ciona intestinalis: II. Peripheral nervous system.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068634

A Drosophila model of Alzheimer's disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068634

Targeting soluble Abeta peptide with Tramiprosate for the treatment of brain amyloidosis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068634

Predictable mosaic transgene expression in ascidian embryos produced with a simple electroporation device

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068634

Optimized green fluorescent protein variants provide improved single cell resolution of transgene expression in ascidian embryos

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068634

Nicastrin functions as a gamma-secretase-substrate receptor

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068634

Pigmentation in the sensory organs of the ascidian larva is essential for normal behavior

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068634

Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068634

Cytosolic and nuclear aggregation of the amyloid beta-peptide following its expression in the endoplasmic reticulum.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068634

Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068634

Tail regression in Ciona intestinalis (Prochordate) involves a Caspase-dependent apoptosis event associated with ERK activation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068634

Regulation of synaptotagmin gene expression during ascidian embryogenesis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068634

Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect Abeta secretion and APP C-terminal fragment stability.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068634

Sensitization and habituation of the swimming behavior in ascidian larvae to light

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20197417

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A new pathogenic mutation in the APP gene (I716V) increases the relative proportion of A beta 42(43)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20197417

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/DMM.003434

1 reference

29 July 2017

1 reference

29 July 2017

1 reference