Group II metabotropic glutamate receptor stimulation triggers production and release of Alzheimer's amyloid(beta)42 from isolated intact nerve terminals (Q33800559)

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English	Group II metabotropic glutamate receptor stimulation triggers production and release of Alzheimer's amyloid(beta)42 from isolated intact nerve terminals	scientific article

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Group II metabotropic glutamate receptor stimulation triggers production and release of Alzheimer's amyloid(beta)42 from isolated intact nerve terminals (English)

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Europe PubMed Central

29 July 2017

Alzheimer's disease

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Peter Henry St George-Hyslop

object named as

Peter H St George-Hyslop

4

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author name string

Soong Ho Kim

1

1 reference

Europe PubMed Central

29 July 2017

Paul E Fraser

2

1 reference

Europe PubMed Central

29 July 2017

David Westaway

3

1 reference

Europe PubMed Central

29 July 2017

Michelle E Ehrlich

5

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Europe PubMed Central

29 July 2017

Sam Gandy

6

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Europe PubMed Central

29 July 2017

language of work or name

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publication date

1 March 2010

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Europe PubMed Central

29 July 2017

Journal of Neuroscience

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Europe PubMed Central

29 July 2017

30

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Europe PubMed Central

29 July 2017

11

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Europe PubMed Central

29 July 2017

3870-3875

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Europe PubMed Central

29 July 2017

Memantine lowers amyloid-beta peptide levels in neuronal cultures and in APP/PS1 transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857209

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Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

1 reference

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Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus

1 reference

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The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival

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The use of total protein stains as loading controls: an alternative to high-abundance single-protein controls in semi-quantitative immunoblotting

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Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

1 reference

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Presynaptic glutamate receptors: physiological functions and mechanisms of action.

1 reference

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Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo

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Intracellular amyloid-beta in Alzheimer's disease

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FMRP mediates mGluR5-dependent translation of amyloid precursor protein

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Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

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Neuropharmacological profiles of antagonists of group II metabotropic glutamate receptors

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MGS0039: a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity.

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APP processing and synaptic function

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Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites

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Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network

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Pharmacological agents acting at subtypes of metabotropic glutamate receptors

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Human metabotropic glutamate receptor 2 couples to the MAP kinase cascade in chinese hamster ovary cells.

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Glutamate-stimulated secretion of amyloid precursor protein from cortical rat brain slices.

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Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation

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Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide

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Protein phosphorylation regulates relative utilization of processing pathways for Alzheimer beta/A4 amyloid precursor protein

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Increase in extracellular NCAM and amyloid precursor protein following induction of long-term potentiation in the dentate gyrus of anaesthetized rats.

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Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors

1 reference

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The metabotropic glutamate receptors: structure and functions

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Biochemical characterization of a filtered synaptoneurosome preparation from guinea pig cerebral cortex: cyclic adenosine 3':5'-monophosphate-generating systems, receptors, and enzymes

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beta-Amyloid peptides impair PKC-dependent functions of metabotropic glutamate receptors in prefrontal cortical neurons

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Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease

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Increased cell proliferation in the adult mouse hippocampus following chronic administration of group II metabotropic glutamate receptor antagonist, MGS0039.

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Activation of group II metabotropic glutamate receptors underlies microglial reactivity and neurotoxicity following stimulation with chromogranin A, a peptide up-regulated in Alzheimer's disease.

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Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

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Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors

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Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as

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The spectrum of behavioral changes in Alzheimer's disease.

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Identifiers

10.1523/JNEUROSCI.4717-09.2010

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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