Induction of p53-independent apoptosis by the adenovirus E4orf4 protein requires binding to the Balpha subunit of protein phosphatase 2A. (Q33810466)

29 July 2017

title

Induction of p53-independent apoptosis by the adenovirus E4orf4 protein requires binding to the Balpha subunit of protein phosphatase 2A. (English)

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29 July 2017

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R C Marcellus

1

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29 July 2017

H Chan

2

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29 July 2017

D Paquette

3

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29 July 2017

S Thirlwell

4

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29 July 2017

D Boivin

5

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29 July 2017

P E Branton

6

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29 July 2017

language of work or name

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1 September 2000

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29 July 2017

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29 July 2017

volume

74

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29 July 2017

issue

17

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29 July 2017

page(s)

7869-7877

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Cloning and characterization of B delta, a novel regulatory subunit of protein phosphatase 2A

29 July 2017

cites work

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4 July 2018

Viruses and Apoptosis

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Induction of apoptosis by adenovirus E4orf4 protein is specific to transformed cells and requires an interaction with protein phosphatase 2A.

4 July 2018

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The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis

4 July 2018

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Regulation of adenovirus alternative RNA splicing by dephosphorylation of SR proteins

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E4orf4, a novel adenovirus death factor that induces p53-independent apoptosis by a pathway that is not inhibited by zVAD-fmk

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4 July 2018

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p300 binding by E1A cosegregates with p53 induction but is dispensable for apoptosis.

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm

4 July 2018

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4 July 2018

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Adenovirus E4 open reading frame 4 protein autoregulates E4 transcription by inhibiting E1A transactivation of the E4 promoter

4 July 2018

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4 July 2018

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Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor

4 July 2018

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Identification of a novel protein phosphatase 2A regulatory subunit highly expressed in muscle

4 July 2018

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The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein

4 July 2018

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High complexity in the expression of the B' subunit of protein phosphatase 2A0. Evidence for the existence of at least seven novel isoforms

4 July 2018

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Molecular cloning of a 74-kDa regulatory subunit (B" or delta) of human protein phosphatase 2A

4 July 2018

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Induction of susceptibility to tumor necrosis factor by E1A is dependent on binding to either p300 or p105-Rb and induction of DNA synthesis

4 July 2018

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Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth

4 July 2018

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4 July 2018

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Structure and expression of a 72-kDa regulatory subunit of protein phosphatase 2A. Evidence for different size forms produced by alternative splicing

30 October 2018

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Identification and characterization of a nerve growth factor-stimulated mitogen-activated protein kinase activator in PC12 cells

4 July 2018

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Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

4 July 2018

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Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

4 July 2018

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Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53.

4 July 2018

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Phosphorylation at the carboxy terminus of the 55-kilodalton adenovirus type 5 E1B protein regulates transforming activity

4 July 2018

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4 July 2018

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Adenovirus E4orf4 protein binds to protein phosphatase 2A, and the complex down regulates E1A-enhanced junB transcription.

4 July 2018

1 reference

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Comparison of heterotrimeric protein phosphatase 2A containing different B subunits.

4 July 2018

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Different oligomeric forms of protein phosphatase 2A activate and inhibit simian virus 40 DNA replication

4 July 2018

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4 July 2018

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Identification of a new family of protein phosphatase 2A regulatory subunits

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure

4 July 2018

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Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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The third subunit of protein phosphatase 2A (PP2A), a 55-kilodalton protein which is apparently substituted for by T antigens in complexes with the 36- and 63-kilodalton PP2A subunits, bears little resemblance to T antigens

4 July 2018

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4 July 2018

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4 July 2018

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Adenovirus E4orf4 protein reduces phosphorylation of c-Fos and E1A proteins while simultaneously reducing the level of AP-1

4 July 2018

1 reference

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The 19-Kilodalton Adenovirus E1B Transforming Protein Inhibits Programmed Cell Death and Prevents Cytolysis by Tumor Necrosis Factor α

4 July 2018

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Two adenovirus proteins with redundant activities in virus growth facilitates tripartite leader mRNA accumulation

4 July 2018

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Diversity in the regulatory B-subunits of protein phosphatase 2A: identification of a novel isoform highly expressed in brain

30 October 2018

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Drosophila mutants in the 55 kDa regulatory subunit of protein phosphatase 2A show strongly reduced ability to dephosphorylate substrates of p34cdc2.

30 October 2018

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Serine/threonine protein phosphatases in the control of cell function

30 October 2018

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12 December 2020

Adenovirus E1A proteins induce apoptosis by both p53-dependent and p53-independent mechanisms

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Adenovirus E1B 19-kDa death suppressor protein interacts with Bax but not with Bad

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12 December 2020

Role of protein phosphatase 2A in the regulation of mitogen-activated protein kinase activity in ventricular cardiomyocytes

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12 December 2020

E1A-induced processing of procaspase-8 can occur independently of FADD and is inhibited by Bcl-2

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12 December 2020

cAMP acts in synergy with E1A protein to activate transcription of the adenovirus early genes E4 and E1A

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12 December 2020

DNA-binding activity of the adenovirus-induced E4F transcription factor is regulated by phosphorylation

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12 December 2020

Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases

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12 December 2020

10.1128/JVI.74.17.7869-7877.2000

Identifiers

DOI

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29 July 2017

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29 July 2017

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