IL-18 induces profibrotic renal tubular cell injury via STAT3 activation (Q33816800)

29 July 2017

IL-18 induces profibrotic renal tubular cell injury via STAT3 activation (English)

1 reference

29 July 2017

Futoshi Matsui

1

1 reference

29 July 2017

Audrey Rhee

2

1 reference

29 July 2017

Karen L Hile

3

1 reference

29 July 2017

Hongji Zhang

4

1 reference

29 July 2017

Kirstan K Meldrum

5

1 reference

29 July 2017

31 July 2013

1 reference

American Journal of Physiology - Renal Physiology

29 July 2017

1 reference

29 July 2017

305

1 reference

29 July 2017

F1014-21

1 reference

29 July 2017

7

1 reference

The role of the Janus kinase family/signal transducer and activator of transcription signaling pathway in fibrotic renal disease

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

IL-18 mediates proapoptotic signaling in renal tubular cells through a Fas ligand-dependent mechanism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

Knockdown of Stat3 activity in vivo prevents diabetic glomerulopathy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

The role of interleukin-18 in renal injury

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

IL-18 in autoimmunity: review

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

Interleukin-18 as a potential therapeutic target in chronic autoimmune/inflammatory conditions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

STAT3 attenuates EGFR-mediated ERK activation and cell survival during oxidant stress in mouse proximal tubular cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

PDGF receptor tyrosine kinase inhibitor suppresses mesangial cell proliferation involving STAT3 activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

Interleukin 18 (IL-18) upregulation in acute rejection of kidney allograft.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

Generation and characterization of mice transgenic for human IL-18-binding protein isoform a

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

Evidence that fibroblasts derive from epithelium during tissue fibrosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

Series introduction. JAK-STAT signaling in human disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

Synergy of IL-12 and IL-18 for IFN-gamma gene expression: IL-12-induced STAT4 contributes to IFN-gamma promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

SOCS proteins: negative regulators of cytokine signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

Interferon-gamma-inducing activity of interleukin-18 in the joint with rheumatoid arthritis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

The role of STATs in transcriptional control and their impact on cellular function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

A proinflammatory role for IL-18 in rheumatoid arthritis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

Overview of interleukin-18: more than an interferon-gamma inducing factor.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073972

Angiotensin II blockade prevents hyperglycemia-induced activation of JAK and STAT proteins in diabetic rat kidney glomeruli

28 July 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00620.2012

Mechanisms of renal injury and progression of renal disease in congenital obstructive nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00620.2012

Interleukin-18 and the pathogenesis of inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00620.2012

Severe hepatic injury in interleukin 18 (IL-18) transgenic mice: a key role for IL-18 in regulating hepatocyte apoptosis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00620.2012

Suppressors of cytokine signaling inhibit tubular epithelial cell-myofibroblast transdifferentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00620.2012

Differential effect of IL-18 on endothelial cell apoptosis mediated by TNF-alpha and Fas (CD95).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00620.2012

Inhibition of JAK2 protects renal endothelial and epithelial cells from oxidative stress and cyclosporin A toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00620.2012

Suppressors of cytokine signaling abrogate diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00620.2012

Jak/STAT signaling is involved in the inflammatory infiltration of the kidneys in MRL/lpr mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00620.2012

Gas6 induces mesangial cell proliferation via latent transcription factor STAT3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00620.2012

Contrasting roles for STAT4 and STAT6 signal transduction pathways in murine renal ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00620.2012

Expression and activation of STAT3 in chronic proliferative immune complex glomerulonephritis and the effect of fosinopril

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00620.2012

Correlation of renal tubular epithelial cell-derived interleukin-18 up-regulation with disease activity in MRL-Faslpr mice with autoimmune lupus nephritis

21 January 2018

1 reference

12 December 2020

Ischemia/reperfusion-induced IFN-gamma up-regulation: involvement of IL-12 and IL-18

1 reference

12 December 2020

Signal transducer and activator of transcription 3 involvement in the development of renal interstitial fibrosis after unilateral ureteral obstruction

1 reference

12 December 2020

Blockage of JAK/STAT signalling attenuates renal ischaemia-reperfusion injury in rat

1 reference

12 December 2020

Activation of signal transducer and activator of transcription 3 correlates with cell proliferation and renal injury in human glomerulonephritis

1 reference

12 December 2020

10.1152/AJPRENAL.00620.2012

Identifiers

DOI

1 reference

29 July 2017

1 reference

29 July 2017

1 reference