A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy (Q39697103)

14 September 2017

A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy (English)

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14 September 2017

Maoyin Pang

1

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14 September 2017

Li Ma

2

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14 September 2017

Rujun Gong

3

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14 September 2017

Evelyn Tolbert

4

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14 September 2017

Haiping Mao

5

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14 September 2017

Murugavel Ponnusamy

6

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14 September 2017

Y Eugene Chin

7

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14 September 2017

Haidong Yan

8

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14 September 2017

Lance D Dworkin

9

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14 September 2017

Shougang Zhuang

10

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14 September 2017

language of work or name

English

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publication date

2 June 2010

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14 September 2017

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14 September 2017

78

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14 September 2017

257-268

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14 September 2017

3

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https://scigraph.springernature.com/pub.10.1038/ki.2010.154

14 September 2017

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cites work

Cellular and molecular mechanisms of fibrosis

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Mechanisms of disease: Fibroblasts--a new look at an old problem

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Fibroblast activation and myofibroblast generation in obstructive nephropathy

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Renal fibrosis: new insights into the pathogenesis and therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

The role of epithelial-to-mesenchymal transition in renal fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

TGF-beta signaling and the fibrotic response

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Pathobiology of transforming growth factor beta in cancer, fibrosis and immunologic disease, and therapeutic considerations

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

TGF-beta signaling in renal disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Inflammatory mediators and growth factors in obstructive renal injury

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Cytokines in epithelial-mesenchymal transition: a new insight into obstructive nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Proinflammatory gene expression and macrophage recruitment in the rat remnant kidney

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

STAT proteins and transcriptional responses to extracellular signals

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Transcriptional control mechanism of fibrinogen gene expression.

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-beta1 production.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

STAT3: an important regulator of multiple cytokine functions.

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

STAT proteins: novel molecular targets for cancer drug discovery

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Cross-talk between IL-6 and TGF-beta signaling in hepatoma cells

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Activation of Stat3 preassembled with platelet-derived growth factor beta receptors requires Src kinase activity

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Analysis of Stat3 (signal transducer and activator of transcription 3) dimerization by fluorescence resonance energy transfer in living cells

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Cytokine profiling and Stat3 phosphorylation in epithelial-mesenchymal interactions between keloid keratinocytes and fibroblasts

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Signal transducer and activator of transcription 3 involvement in the development of renal interstitial fibrosis after unilateral ureteral obstruction

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

A road map for those who don't know JAK-STAT

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-{beta} and STAT3 activation.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Role of matrix metalloproteinases in renal pathophysiologies

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Role of Wnt/beta-catenin signaling pathway in epithelial-mesenchymal transition of human prostate cancer induced by hypoxia-inducible factor-1alpha

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Cadherin–catenin complex and transcription factor Snail-1 in spindle cell carcinoma of the head and neck

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Assessment and prognostic significance of mitotic index using the mitosis marker phospho-histone H3 in low and intermediate-grade infiltrating astrocytomas.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Basal c-Jun N-terminal kinases promote mitotic progression through histone H3 phosphorylation

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https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Interacting roles of myofibroblasts, apoptosis and fibrogenic growth factors in the pathogenesis of renal tubulo-interstitial fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Interleukin-1beta induces human proximal tubule cell injury, alpha-smooth muscle actin expression and fibronectin production

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Activation of signal transducer and activator of transcription 3 correlates with cell proliferation and renal injury in human glomerulonephritis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Interleukin-8 and the chemokine family.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Monocyte chemoattractant protein-1 promotes the development of diabetic renal injury in streptozotocin-treated mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Possible participation of a JAK2 signaling pathway in recombinant rat interleukin-5-induced prolongation of rat eosinophil survival

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Obstructive nephropathy: towards biomarker discovery and gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Glycogen synthase kinase 3beta: a novel marker and modulator of inflammatory injury in chronic renal allograft disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.154

7 January 2021

Identifiers

DOI

10.1038/KI.2010.154

1 reference

Dimensions Publication ID

14 September 2017

1017404824

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Fatcat ID

release_y6mzn57rhzga3gwrdprs2geh2e

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/y6mzn57rhzga3gwrdprs2geh2e

24 November 2022

mapped directly with Wikidata item

1 reference