Granzyme B releases vascular endothelial growth factor from extracellular matrix and induces vascular permeability (Q33818704)

29 July 2017

Granzyme B releases vascular endothelial growth factor from extracellular matrix and induces vascular permeability (English)

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29 July 2017

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Alon Hendel

1

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29 July 2017

Ivy Hsu

series ordinal

2

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29 July 2017

David J Granville

series ordinal

3

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29 July 2017

5 May 2014

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29 July 2017

Laboratory Investigation

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29 July 2017

94

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29 July 2017

716-725

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29 July 2017

7

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https://scigraph.springernature.com/pub.10.1038/labinvest.2014.62

29 July 2017

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cites work

Granzyme B degrades extracellular matrix and contributes to delayed wound closure in apolipoprotein E knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Granzyme B in injury, inflammation, and repair

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Update of immune events in the murine contact hypersensitivity model: toward the understanding of allergic contact dermatitis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Granzyme B cleaves decorin, biglycan and soluble betaglycan, releasing active transforming growth factor-β1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Vascular hyperpermeability, angiogenesis, and stroma generation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1α.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Granzyme B contributes to extracellular matrix remodeling and skin aging in apolipoprotein E knockout mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Binding to the extracellular matrix and proteolytic processing: two key mechanisms regulating vascular endothelial growth factor action

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Extracellular matrix, inflammation, and the angiogenic response

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Granzymes in age-related cardiovascular and pulmonary diseases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Perforin-independent extracellular granzyme B activity contributes to abdominal aortic aneurysm

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Cross-talk between vascular endothelial growth factor and matrix metalloproteinases in the induction of neovascularization in vivo

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Vascular regression and survival are differentially regulated by MT1-MMP and TIMPs in the aortic ring model of angiogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Neutrophil elastase cleaves VEGF to generate a VEGF fragment with altered activity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Epidermal vascular endothelial growth factor production is required for permeability barrier homeostasis, dermal angiogenesis, and the development of epidermal hyperplasia: implications for the pathogenesis of psoriasis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

VEGF-A and the induction of pathological angiogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Growth factor binding to the pericellular matrix and its importance in tissue engineering

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Autocrine VEGF signaling is required for vascular homeostasis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Angiogenesis and chronic inflammation: cause or consequence?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Heparin-II domain of fibronectin is a vascular endothelial growth factor-binding domain: enhancement of VEGF biological activity by a singular growth factor/matrix protein synergism

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Vascular endothelial growth factor localization in the adult.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Novel vascular endothelial growth factor binding domains of fibronectin enhance vascular endothelial growth factor biological activity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

Engineering the Growth Factor Microenvironment with Fibronectin Domains to Promote Wound and Bone Tissue Healing

4 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.62

Elevation of plasma granzyme B levels after acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.62

Granzyme B is a novel interleukin-18 converting enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.62

Granzyme B cleavage of fibronectin disrupts endothelial cell adhesion, migration and capillary tube formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.62

Discovery of potent, selective human granzyme B inhibitors that inhibit CTL mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.62

Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.62

Pathophysiological consequences of VEGF-induced vascular permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.62

Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.62

Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: implications for ascites formation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074428

The 12th-14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain

30 October 2018

1 reference

12 December 2020

Vascular reactions to histamine, histamine-liberator and leukotaxine in the skin of guinea-pigs

1 reference

12 December 2020

Expression of granzymes A and B in synovial tissue from patients with rheumatoid arthritis and osteoarthritis

1 reference

12 December 2020

Signal transduction by vascular endothelial growth factor receptors

1 reference

12 December 2020

Regulation of angiostatin production by matrix metalloproteinase-2 in a model of concomitant resistance

1 reference

12 December 2020

10.1038/LABINVEST.2014.62

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29 July 2017

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1 reference

29 July 2017

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