Insulin-like growth factor 1-mediated hyperthermia involves anterior hypothalamic insulin receptors (Q33823428)

29 July 2017

Insulin-like growth factor 1-mediated hyperthermia involves anterior hypothalamic insulin receptors (English)

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29 July 2017

1 reference

7

Tamas Bartfai

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Olivia Osborn

object named as

Olivia Osborn

2

0 references

Manuel Sanchez-Alavez

object named as

Manuel Sanchez-Alavez

1

0 references

C. Ronald Kahn

6

object named as

C Ronald Kahn

1 reference

29 July 2017

Iustin V Tabarean

3

1 reference

29 July 2017

Kristina H Holmberg

4

1 reference

29 July 2017

James Eberwine

5

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29 July 2017

language of work or name

English

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publication date

17 February 2011

1 reference

Journal of Biological Chemistry

29 July 2017

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29 July 2017

286

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29 July 2017

14983-14990

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29 July 2017

17

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Insulin causes hyperthermia by direct inhibition of warm-sensitive neurons

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Identification and importance of brown adipose tissue in adult humans

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Genetic polymorphism in long-lived people: cues for the presence of an insulin/IGF-pathway-dependent network affecting human longevity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Central control of thermogenesis in mammals

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Functionally significant insulin-like growth factor I receptor mutations in centenarians

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

A thermosensory pathway that controls body temperature

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Modifying IGF1 activity: an approach to treat endocrine disorders, atherosclerosis and cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Metabolic aspects of the extreme longevity.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

AKT/PKB signaling: navigating downstream

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

The role of insulin receptor isoforms and hybrid insulin/IGF-I receptors in human cancer.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Transgenic mice with a reduced core body temperature have an increased life span

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Control of aging and longevity by IGF-I signaling

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

The plasticity of aging: insights from long-lived mutants

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Serum insulin-like growth factor-1 in centenarians: implications of IGF-1 as a rapid turnover protein

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Role of the preoptic-anterior hypothalamus in thermoregulation and fever

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Role of brain insulin receptor in control of body weight and reproduction.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Towards a molecular understanding of adaptive thermogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Serum levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 in healthy centenarians: relationship with plasma leptin and lipid concentrations, insulin action, and cognitive function.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Targeted disruption of the insulin receptor gene in the mouse results in neonatal lethality

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

The insulin-like growth factor-I receptor. Structure, ligand-binding mechanism and signal transduction.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Localization of Type I Insulin-Like Growth Factor Receptor Messenger RNA in the Adult Rat Brain byin SituHybridization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Analysis of gene expression in single live neurons

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Identification of insulin in rat brain

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Concentrations of insulin and insulin receptors in the brain are independent of peripheral insulin levels. Studies of obese and streptozotocin-treated rodents

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study

4 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188540

Trial of insulinlike growth factor I therapy for patients with extreme insulin resistance syndromes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188540

The hypothalamic insulin-like growth factor-1 receptor and its relationship to gonadotropin-releasing hormones neurones during postnatal development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188540

Androgens promote oocyte insulin-like growth factor I expression and initiation of follicle development in the primate ovary.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188540

Localization of the insulin-like growth factor I receptor in the cerebellum and hypothalamus of adult rats: an electron microscopic study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188540

Alterations in insulin-like growth factor-1 gene and protein expression and type 1 insulin-like growth factor receptors in the brains of ageing rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188540

Central resistance to the inhibitory effects of leptin on stimulated insulin secretion with aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188540

Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188540

Bovine growth hormone transgenic mice are resistant to diet-induced obesity but develop hyperphagia, dyslipidemia, and diabetes on a high-fat diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188540

Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Hypothalamic insulin signaling is required for inhibition of glucose production

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Reduced levels of thyroid hormones, insulin, and glucose, and lower body core temperature in the growth hormone receptor/binding protein knockout mouse.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083203

Strain variation in the response of body temperature to dietary restriction

29 October 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188540

Localization and Characterization of Insulin-Like Growth Factor-I Receptors in Rat Brain and Pituitary Gland Using in vitro Autoradiography and Computerized Densitometry* A Distinct Distribution from Insulin Receptors

21 January 2018

1 reference

12 December 2020

Interactions of estrogens and insulin-like growth factor-I in the brain: implications for neuroprotection

1 reference

12 December 2020

Effects of moderate caloric restriction on cortical microvascular density and local cerebral blood flow in aged rats

1 reference

12 December 2020

Early neonatal death in mice homozygous for a null allele of the insulin receptor gene

1 reference

12 December 2020

Growth factors and vascular smooth muscle cell growth responses

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.188540

1 reference

29 July 2017

1 reference

29 July 2017

1 reference