Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches (Q33830824)

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English	Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches	scientific article

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scholarly article

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29 July 2017

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches (English)

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Aaron L Oom

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Dan H Barouch

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Ian Andrew Wilson

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Ian A Wilson

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Laura E McCoy

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David C. Montefiori

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David C Montefiori

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Colin Havenar-Daughton

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William R Schief

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Dennis R. Burton

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Dennis R Burton

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Andrew B Ward

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Rogier W Sanders

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Rogier W Sanders

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Gabriel Ozorowski

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Gabriel Ozorowski

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Shane Crotty

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Richard T. Wyatt

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Richard T Wyatt

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Celia C LaBranche

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Celia C LaBranche

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Christopher A. Cottrell

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Christopher A Cottrell

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Darrell J Irvine

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Darrell J Irvine

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Devin Sok

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Alba Torrents de la Peña

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Alba Torrents de la Peña

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Matthias Pauthner

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Matthias Pauthner

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Steven W de Taeye

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Steven W de Taeye

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Diane G Carnathan

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Diane G Carnathan

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Kirti Kaushik

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Joseph P. Nkolola

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Raiza Bastidas

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Jon M Steichen

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Talar Tokatlian

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Talar Tokatlian

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Guido Silvestri

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Guido Silvestri

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Shailendra Sharma

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Shailendra K Sharma

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Archana V Boopathy

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Abishek Chandrashekar

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Kimberly M Cirelli

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Alexey M Eroshkin

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Javier Guenaga

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Daniel W Kulp

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Jinyan Liu

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Kai W Post

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Salvatore T Butera

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publication date

1 June 2017

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46

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1073-1088.e6

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6

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Native-like Env trimers as a platform for HIV-1 vaccine design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Germinal Center Lymphocyte Ratios and Successful HIV Vaccines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Sex differences in immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

High-Density Array of Well-Ordered HIV-1 Spikes on Synthetic Liposomal Nanoparticles Efficiently Activate B Cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

HIV-1 Envelope Trimer Design and Immunization Strategies To Induce Broadly Neutralizing Antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble Trimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Pathophysiology of T follicular helper cells in humans and mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

T follicular helper cell differentiation, function, and roles in disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies

1 reference

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4 July 2018

Global panel of HIV-1 Env reference strains for standardized assessments of vaccine-elicited neutralizing antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Immune-correlates analysis of an HIV-1 vaccine efficacy trial

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4 July 2018

Germinal centers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5483234

4 July 2018

Correlates of protection induced by vaccination

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4 July 2018

The role of antibodies in HIV vaccines

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4 July 2018

ISCOMs and ISCOMATRIX.

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4 July 2018

Neutralization escape variants of human immunodeficiency virus type 1 are transmitted from mother to infant

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4 July 2018

Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

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4 July 2018

Recommendations for the design and use of standard virus panels to assess neutralizing antibody responses elicited by candidate human immunodeficiency virus type 1 vaccines

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4 July 2018

Antibody neutralization and escape by HIV-1

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4 July 2018

Rapid evolution of the neutralizing antibody response to HIV type 1 infection

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4 July 2018

Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.

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4 July 2018

A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure

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4 July 2018

Identifiers

10.1016/J.IMMUNI.2017.05.007

1 reference

Europe PubMed Central

29 July 2017

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Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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