Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer (Q37482035)

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English	Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer	scientific article

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scholarly article

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Europe PubMed Central

20 August 2017

Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer (English)

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20 August 2017

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Sanjeev Gumber

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Marit J. van Gils

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Marit J van Gils

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Colin Havenar-Daughton

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Colin Havenar-Daughton

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Bali Pulendran

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Rafi Ahmed

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Dennis R. Burton

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Dennis R Burton

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Rogier W Sanders

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Rogier W Sanders

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John P Moore

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Sudhir Pai Kasturi

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Sudhir P Kasturi

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Shane Crotty

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Devin Sok

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Alba Torrents de la Peña

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Alba Torrents de la Peña

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Matthias Pauthner

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Matthias Pauthner

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Bryan Briney

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Steven W de Taeye

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Steven W de Taeye

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Diane G Carnathan

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Diane G Carnathan

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Kirti Kaushik

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Patricia van der Woude

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Samantha M Reiss

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Samantha M Reiss

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author name string

Jennifer S Wood

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Sandy L Rosales

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Michela Locci

12

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Khoa M Le

13

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Ata Ur Rasheed Mohammed

16

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Jessica Huang

17

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AnaPatricia Garcia

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Grégory Seumois

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Guido Silvestri

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publication date

1 November 2016

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2195-2209

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20 August 2017

Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination

1 reference

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Activin A programs the differentiation of human TFH cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges

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23 August 2017

HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen

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23 August 2017

Complex Antigens Drive Permissive Clonal Selection in Germinal Centers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

HIV-Host Interactions: Implications for Vaccine Design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Visualizing antibody affinity maturation in germinal centers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

CXCL13 is a plasma biomarker of germinal center activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Antibody responses to envelope glycoproteins in HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization

1 reference

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Animal models in HIV-1 protection and therapy

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23 August 2017

Class-switched memory B cells remodel BCRs within secondary germinal centers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Early preservation of CXCR5+ PD-1+ helper T cells and B cell activation predict the breadth of neutralizing antibody responses in chronic HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Early lymphoid responses and germinal center formation correlate with lower viral load set points and better prognosis of simian immunodeficiency virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Antibodies in HIV-1 vaccine development and therapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

IL-12 receptor β1 deficiency alters in vivo T follicular helper cell response in humans

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Broadly neutralizing antiviral antibodies

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

CD4 T follicular helper cell dynamics during SIV infection

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23 August 2017

Functional STAT3 deficiency compromises the generation of human T follicular helper cells.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Germinal centers

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Broad neutralization coverage of HIV by multiple highly potent antibodies

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23 August 2017

A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Follicular helper CD4 T cells (TFH)

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5142765

23 August 2017

Different B cell populations mediate early and late memory during an endogenous immune response

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23 August 2017

Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter

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23 August 2017

Correlates of protection induced by vaccination

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The role of antibodies in HIV vaccines

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Fine-needle aspiration (FNA) biopsy: historical aspects.

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Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

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Human immunodeficiency virus type 1 env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein.

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Comparison of immunity generated by nucleic acid-, MF59-, and ISCOM-formulated human immunodeficiency virus type 1 vaccines in Rhesus macaques: evidence for viral clearance.

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HIV-1 envelope glycoprotein immunogens to induce broadly neutralizing antibodies

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T follicular helper cell differentiation, function, and roles in disease

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Clinical experience with hepatitis B vaccines

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Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble Trimers

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A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood.

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Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique

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Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design

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Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer

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Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection

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A Phase II Study of Two HIV Type 1 Envelope Vaccines, Comparing Their Immunogenicity in Populations at Risk for Acquiring HIV Type 1 Infection

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QS-21 promotes an adjuvant effect allowing for reduced antigen dose during HIV-1 envelope subunit immmunization in humans

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Fine-needle aspiration cytology in the diagnosis of superficial lymphadenopathy: an analysis of 2,418 cases

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10.1016/J.CELREP.2016.10.085

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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