AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants (Q33839428)

29 July 2017

AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants (English)

1 reference

29 July 2017

José F Ruiz

1

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Andrés Aguilera

object named as

Andrés Aguilera

series ordinal

3

0 references

author name string

Belén Gómez-González

series ordinal

2

1 reference

29 July 2017

24 February 2011

1 reference

29 July 2017

1 reference

29 July 2017

7

1 reference

29 July 2017

2

1 reference

29 July 2017

e1002009

1 reference

Creative Commons Attribution 4.0 International

29 July 2017

start time

24 February 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations

5 July 2018

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5 July 2018

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Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity

5 July 2018

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5 July 2018

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Recombination between retrotransposons as a source of chromosome rearrangements in the yeast Saccharomyces cerevisiae

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The transcription elongation complex directs activation-induced cytidine deaminase-mediated DNA deamination

5 July 2018

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Inducible DNA breaks in Ig S regions are dependent on AID and UNG

5 July 2018

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Saccharomyces cerevisiae as a model system to define the chromosomal instability phenotype.

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Fine-structure analysis of activation-induced deaminase accessibility to class switch region R-loops

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Influence of switch region length on immunoglobulin class switch recombination

5 July 2018

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Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

5 July 2018

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Activation-induced cytidine deaminase (AID) can target both DNA strands when the DNA is supercoiled

5 July 2018

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Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA

5 July 2018

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Class-switch recombination: interplay of transcription, DNA deamination and DNA repair

5 July 2018

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Recombinogenic phenotype of human activation-induced cytosine deaminase.

5 July 2018

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Cotranscriptionally Formed DNA:RNA Hybrids Mediate Transcription Elongation Impairment and Transcription-Associated Recombination

5 July 2018

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Transcription-targeted DNA deamination by the AID antibody diversification enzyme

5 July 2018

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Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

5 July 2018

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R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

5 July 2018

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The connection between transcription and genomic instability

5 July 2018

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Mechanisms of chromosomal translocations in B cell lymphomas

5 July 2018

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Hpr1 is preferentially required for transcription of either long or G+C-rich DNA sequences in Saccharomyces cerevisiae.

5 July 2018

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Stimulation of mitotic recombination events by high levels of RNA polymerase II transcription in yeast

5 July 2018

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Frequent chromosomal translocations induced by DNA double-strand breaks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044682

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044682

The yeast HPR1 gene has a functional role in transcriptional elongation that uncovers a novel source of genome instability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044682

RNA:DNA complex formation upon transcription of immunoglobulin switch regions: implications for the mechanism and regulation of class switch recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044682

DNA sequences at immunoglobulin switch region recombination sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044682

Transcription-coupled events associating with immunoglobulin switch region chromatin

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002009

Two levels of protection for the B cell genome during somatic hypermutation.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002009

AID is required for c-myc/IgH chromosome translocations in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002009

Chromosomal translocations in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002009

AID binds to transcription-induced structures in c-MYC that map to regions associated with translocation and hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002009

G-rich proto-oncogenes are targeted for genomic instability in B-cell lymphomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002009

Competition between the RNA transcript and the nontemplate DNA strand during R-loop formation in vitro: a nick can serve as a strong R-loop initiation site

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002009

Transcription-induced cleavage of immunoglobulin switch regions by nucleotide excision repair nucleases in vitro

21 January 2018

1 reference

12 December 2020

The influence of transcriptional orientation on endogenous switch region function

1 reference

12 December 2020

Association of increased spontaneous mutation rates with high levels of transcription in yeast

1 reference

12 December 2020

Chromosomal translocation mechanisms at intronic alu elements in mammalian cells

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1002009

Identifiers

DOI

1 reference

29 July 2017

1 reference

29 July 2017

1 reference

PubMed ID

21383964