FGF21 as a Hepatokine, Adipokine, and Myokine in Metabolism and Diseases (Q33851027)

29 July 2017

title

FGF21 as a Hepatokine, Adipokine, and Myokine in Metabolism and Diseases (English)

1 reference

29 July 2017

Nobuyuki Itoh

1

1 reference

29 July 2017

publication date

7 July 2014

1 reference

Frontiers in Endocrinology

29 July 2017

published in

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29 July 2017

volume

5

1 reference

29 July 2017

page(s)

107

1 reference

Fibroblast growth factor (Fgf) 21 is a novel target gene of the aryl hydrocarbon receptor (AhR).

29 July 2017

cites work

1 reference

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Inventing new medicines: The FGF21 story

5 July 2018

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Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

Stressed Liver and Muscle Call on Adipocytes with FGF21

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

Fibroblast growth factor 21, the endocrine FGF pathway and novel treatments for metabolic syndrome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

Fgf21 impairs adipocyte insulin sensitivity in mice fed a low-carbohydrate, high-fat ketogenic diet

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

Serum levels of the adipokine fibroblast growth factor-21 are increased in preeclampsia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

Expression of fibroblast growth factor-21 in muscle is associated with lipodystrophy, insulin resistance and lipid disturbances in patients with HIV

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

Novel locus including FGF21 is associated with dietary macronutrient intake

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

Mild cold exposure modulates fibroblast growth factor 21 (FGF21) diurnal rhythm in humans: relationship between FGF21 levels, lipolysis, and cold-induced thermogenesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

FGF21 promotes metabolic homeostasis via white adipose and leptin in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

Integrated regulation of hepatic metabolism by fibroblast growth factor 21 (FGF21) in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

FGF21 as an Endocrine Regulator in Lipid Metabolism: From Molecular Evolution to Physiology and Pathophysiology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

Thermogenic activation induces FGF21 expression and release in brown adipose tissue.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

Serum levels of FGF-21 are increased in coronary heart disease patients and are independently associated with adverse lipid profile

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

Plasma concentrations of fibroblast growth factors 21 and 19 in patients with Cushing's syndrome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

FGF21 is an Akt-regulated myokine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083219

Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver.

5 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00107

Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00107

Fibroblast growth factor 21 protects against cardiac hypertrophy in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00107

The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00107

Associations of fibroblast growth factor 21 gene 3' untranslated region single-nucleotide polymorphisms with metabolic syndrome, obesity, and diabetes in a Han Chinese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00107

Serum fibroblast growth factor-21 levels are associated with carotid atherosclerosis independent of established cardiovascular risk factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00107

Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00107

Fibroblast growth factor 21 is a sensitive biomarker of mitochondrial disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00107

Plasma concentrations of fibroblast growth factors 19 and 21 in patients with anorexia nervosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00107

Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25071723

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FENDO.2014.00107

1 reference

29 July 2017

1 reference

29 July 2017

1 reference