Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection (Q33854184)

29 July 2017

Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection (English)

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29 July 2017

9

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29 July 2017

Thomas J Cradick

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author name string

Lin Ye

1

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29 July 2017

Jiaming Wang

2

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29 July 2017

Ashley I Beyer

3

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29 July 2017

Fernando Teque

4

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29 July 2017

Zhongxia Qi

6

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29 July 2017

Judy C Chang

7

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29 July 2017

Gang Bao

8

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29 July 2017

Jingwei Yu

10

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29 July 2017

Jay A Levy

11

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29 July 2017

Yuet Wai Kan

12

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29 July 2017

language of work or name

English

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publication date

9 June 2014

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

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29 July 2017

111

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29 July 2017

26

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29 July 2017

9591-9596

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Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Optimization of scarless human stem cell genome editing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

piggyBac transposase tools for genome engineering

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

RNA-guided human genome engineering via Cas9

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Multiplex genome engineering using CRISPR/Cas systems

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

A TALE nuclease architecture for efficient genome editing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Inhibition of HIV-1 infection by a unique short hairpin RNA to chemokine receptor 5 delivered into macrophages through hematopoietic progenitor cell transduction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Reprogramming of human somatic cells to pluripotency with defined factors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

An improved zinc-finger nuclease architecture for highly specific genome editing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Complete knockdown of CCR5 by lentiviral vector-expressed siRNAs and protection of transgenic macrophages against HIV-1 infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Gene therapy: therapeutic gene causing lymphoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Global distribution of the CCR5 gene 32-basepair deletion.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084478

Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1407473111

Homozygous and heterozygous CCR5-Delta32 genotypes are associated with resistance to HIV infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1407473111

Specific transduction of HIV-susceptible cells for CCR5 knockdown and resistance to HIV infection: a novel method for targeted gene therapy and intracellular immunization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1407473111

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1407473111

Blood cell-derived induced pluripotent stem cells free of reprogramming factors generated by Sendai viral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1407473111

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1407473111

DNA targeting specificity of RNA-guided Cas9 nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1407473111

Maintenance of proliferative capacity and retroviral transduction efficiency of human fetal CD38(-)/CD34(++) stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1407473111

Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1407473111

Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1407473111

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1407473111

21 January 2018

Identifiers

DOI

10.1073/PNAS.1407473111

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29 July 2017

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29 July 2017

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