EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiation (Q33877028)

29 July 2017

title

EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiation (English)

1 reference

29 July 2017

Miroslawa Siatecka

1

1 reference

29 July 2017

Felix Lohmann

series ordinal

2

1 reference

29 July 2017

Sujin Bao

series ordinal

3

1 reference

29 July 2017

James J Bieker

series ordinal

4

1 reference

29 July 2017

language of work or name

English

0 references

publication date

5 April 2010

1 reference

Molecular and Cellular Biology

29 July 2017

published in

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29 July 2017

volume

30

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29 July 2017

issue

11

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29 July 2017

page(s)

2811-2822

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E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells

29 July 2017

cites work

1 reference

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EKLF/KLF1 controls cell cycle entry via direct regulation of E2f2.

5 July 2018

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Failure of terminal erythroid differentiation in EKLF-deficient mice is associated with cell cycle perturbation and reduced expression of E2F2.

5 July 2018

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Acetylation of EKLF is essential for epigenetic modification and transcriptional activation of the beta-globin locus

5 July 2018

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EKLF restricts megakaryocytic differentiation at the benefit of erythrocytic differentiation

5 July 2018

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Non-random subcellular distribution of variant EKLF in erythroid cells

5 July 2018

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Hematopoiesis: an evolving paradigm for stem cell biology

5 July 2018

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Sumoylation of EKLF promotes transcriptional repression and is involved in inhibition of megakaryopoiesis

5 July 2018

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Deregulated E2f-2 underlies cell cycle and maturation defects in retinoblastoma null erythroblasts

5 July 2018

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Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis

5 July 2018

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Novel role for EKLF in megakaryocyte lineage commitment

5 July 2018

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Foxo3 is required for the regulation of oxidative stress in erythropoiesis

5 July 2018

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Erythroid Kruppel-like factor regulates the G1 cyclin dependent kinase inhibitor p18INK4c

5 July 2018

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Lineage-specific activators affect beta-globin locus chromatin in multipotent hematopoietic progenitors

5 July 2018

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Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor.

5 July 2018

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ETO2 coordinates cellular proliferation and differentiation during erythropoiesis

5 July 2018

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A global role for EKLF in definitive and primitive erythropoiesis

5 July 2018

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KLF4, p21 and context-dependent opposing forces in cancer

5 July 2018

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Chromatin domain activation via GATA-1 utilization of a small subset of dispersed GATA motifs within a broad chromosomal region

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Repression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Preferential adhesion mediated by Hibris and Roughest regulates morphogenesis and patterning in the Drosophila eye.

5 July 2018

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The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability

5 July 2018

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The E2F transcriptional network: old acquaintances with new faces

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Stage-specific repression by the EKLF transcriptional activator

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Global regulation of erythroid gene expression by transcription factor GATA-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

BRG1 controls the activity of the retinoblastoma protein via regulation of p21CIP1/WAF1/SDI.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Analysis of multiple genomic sequence alignments: a web resource, online tools, and lessons learned from analysis of mammalian SCL loci.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Role for BRG1 in cell cycle control and tumor suppression

5 July 2018

1 reference

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GATA-1-mediated proliferation arrest during erythroid maturation.

5 July 2018

1 reference

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Formation of a tissue-specific histone acetylation pattern by the hematopoietic transcription factor GATA-1.

5 July 2018

1 reference

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Cell cycle regulators and hematopoiesis

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

New insights into erythropoiesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Sibling rivalry in the E2F family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

KLF6, a candidate tumor suppressor gene mutated in prostate cancer

5 July 2018

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E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Class I histone deacetylases sequentially interact with MyoD and pRb during skeletal myogenesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Unanticipated repression function linked to erythroid Krüppel-like factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: inhibition of the myogenic program

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Site-specific acetylation by p300 or CREB binding protein regulates erythroid Krüppel-like factor transcriptional activity via its interaction with the SWI-SNF complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Erythroid Kruppel-like factor (EKLF) coordinates erythroid cell proliferation and hemoglobinization in cell lines derived from EKLF null mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Coordinating cell proliferation and differentiation

5 July 2018

1 reference

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The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter

5 July 2018

1 reference

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A GATA box in the GATA-1 gene hematopoietic enhancer is a critical element in the network of GATA factors and sites that regulate this gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Acetylation and modulation of erythroid Krüppel-like factor (EKLF) activity by interaction with histone acetyltransferases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Isolation, genomic structure, and expression of human erythroid Krüppel-like factor (EKLF)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

Erythroid Krüppel-like factor exhibits an early and sequentially localized pattern of expression during mammalian erythroid ontogeny.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876526

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5 July 2018

1 reference

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p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

5 July 2018

1 reference

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A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins

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1 reference

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1 reference

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Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

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1 reference

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1 reference

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29 October 2018

1 reference

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Different sequence requirements for expression in erythroid and megakaryocytic cells within a regulatory element upstream of the GATA-1 gene.

29 October 2018

1 reference

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29 October 2018

1 reference

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29 October 2018

1 reference

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1 reference

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1 reference

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12 December 2020

E2f4 regulates fetal erythropoiesis through the promotion of cellular proliferation

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Analyses of beta-thalassemia mutant DNA interactions with erythroid Krüppel-like factor (EKLF), an erythroid cell-specific transcription factor

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Identifiers

DOI

10.1128/MCB.01016-09

1 reference

29 July 2017

1 reference

29 July 2017

1 reference