Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferation (Q33877608)

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English	Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferation	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferation (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

Laure Voisin

1

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Europe PubMed Central

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29 July 2017

Marc K Saba-El-Leil

2

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Europe PubMed Central

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29 July 2017

Catherine Julien

3

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Europe PubMed Central

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29 July 2017

Christophe Frémin

4

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29 July 2017

Sylvain Meloche

5

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29 July 2017

language of work or name

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publication date

5 April 2010

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29 July 2017

Molecular and Cellular Biology

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Europe PubMed Central

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29 July 2017

30

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Europe PubMed Central

PubMed publication ID

29 July 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

2918-2932

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines

1 reference

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28 July 2018

Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors

1 reference

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The RSK family of kinases: emerging roles in cellular signalling

1 reference

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ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

1 reference

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28 July 2018

Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels

1 reference

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28 July 2018

Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma

1 reference

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28 July 2018

The RAS-dependent ERF control of cell proliferation and differentiation is mediated by c-Myc repression

1 reference

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28 July 2018

Cellular senescence: when bad things happen to good cells

1 reference

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28 July 2018

The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition

1 reference

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28 July 2018

Differential regulation and properties of MAPKs

1 reference

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Modulation of replicative senescence of diploid human cells by nuclear ERK signaling

1 reference

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28 July 2018

Distinct functions for ERKs?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

28 July 2018

ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

28 July 2018

Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression.

1 reference

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28 July 2018

ERK2 is required for efficient terminal differentiation of skeletal myoblasts

1 reference

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28 July 2018

The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

1 reference

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28 July 2018

G1 cell-cycle control and cancer

1 reference

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28 July 2018

Essential role for ERK2 mitogen-activated protein kinase in placental development

1 reference

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Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

1 reference

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28 July 2018

Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation

1 reference

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An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets

1 reference

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28 July 2018

An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development

1 reference

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28 July 2018

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

1 reference

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28 July 2018

Regulation of cell cycle progression and apoptosis by the Ras/Raf/MEK/ERK pathway (Review).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

28 July 2018

Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

28 July 2018

Lack of Elk-1 phosphorylation and dysregulation of the extracellular regulated kinase signaling pathway in senescent human fibroblast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

28 July 2018

Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells

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28 July 2018

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

28 July 2018

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

28 July 2018

Significance of nuclear relocalization of ERK1/2 in reactivation of c-fos transcription and DNA synthesis in senescent fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

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Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

1 reference

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28 July 2018

Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

28 July 2018

Signal transduction through MAP kinase cascades

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

28 July 2018

MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

28 July 2018

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

28 July 2018

Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro

1 reference

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Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

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Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability

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An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control

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28 July 2018

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

1 reference

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Identification of substrate recognition determinants for human ERK1 and ERK2 protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

28 July 2018

Identification of multiple extracellular signal-regulated kinases (ERKs) with antipeptide antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

28 July 2018

Total ERK1/2 activity regulates cell proliferation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

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Multiple division cycles and long-term survival of hepatocytes are distinctly regulated by extracellular signal-regulated kinases ERK1 and ERK2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

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The N-terminal domain of ERK1 accounts for the functional differences with ERK2

1 reference

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Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion.

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Differential mRNA distribution of components of the ERK/MAPK signalling cascade in the adult mouse brain

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1 reference

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The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

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p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

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MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

29 October 2018

The MAP kinase pathway is required for entry into mitosis and cell survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876689

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20368360

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20368360

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20368360

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20368360

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inferred from PubMed ID database lookup

SV40-Mediated immortalization

1 reference

https://pubmed.ncbi.nlm.nih.gov/20368360

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00131-10

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Europe PubMed Central

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29 July 2017

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24 November 2022

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Europe PubMed Central

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29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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