Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model (Q33893466)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23124828%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model (English)

1 reference

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17 February 2020

1 reference

2

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17 February 2020

Mona Dvir-Ginzberg

3

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17 February 2020

author name string

Odile Gabay

1

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17 February 2020

Viktoria Gagarina

4

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17 February 2020

Kristien J Zaal

5

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17 February 2020

Yingjie Song

6

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17 February 2020

Xiao Hong He

7

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17 February 2020

Michael W McBurney

8

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17 February 2020

publication date

1 January 2013

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17 February 2020

published in

Arthritis and Rheumatism

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17 February 2020

volume

65

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17 February 2020

issue

1

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17 February 2020

page(s)

159-166

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describes a project that uses

17 February 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4095888/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Increased apoptotic chondrocytes in articular cartilage from adult heterozygous SirT1 mice.

1 reference

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Role of sirtuins, calorie restriction and physical activity in aging

5 July 2018

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75-kd sirtuin 1 blocks tumor necrosis factor α-mediated apoptosis in human osteoarthritic chondrocytes

5 July 2018

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ADAMTS-4 and ADAMTS-5: key enzymes in osteoarthritis

5 July 2018

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Tumor necrosis factor α-mediated cleavage and inactivation of SirT1 in human osteoarthritic chondrocytes

5 July 2018

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The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse.

5 July 2018

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SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2.

5 July 2018

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SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway.

5 July 2018

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The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice

5 July 2018

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Co-culture of mechanically injured cartilage with joint capsule tissue alters chondrocyte expression patterns and increases ADAMTS5 production.

5 July 2018

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Silent information regulator, Sirtuin 1, and age-related diseases

5 July 2018

1 reference

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Analysis of skeletal ontogenesis through differential staining of bone and cartilage

5 July 2018

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Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase.

5 July 2018

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Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II

5 July 2018

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Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

5 July 2018

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Sirtuins in mammals: insights into their biological function

5 July 2018

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Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

5 July 2018

1 reference

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Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

5 July 2018

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The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis

5 July 2018

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Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

5 July 2018

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The role of cytokines as inflammatory mediators in osteoarthritis: lessons from animal models

5 July 2018

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SIRT1 regulation of apoptosis of human chondrocytes

5 July 2018

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SirT1 catalytic activity is required for male fertility and metabolic homeostasis in mice.

21 January 2018

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21 January 2018

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21 January 2018

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The absence of SIR2alpha protein has no effect on global gene silencing in mouse embryonic stem cells.

21 January 2018

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Stress-induced signaling pathways in hyalin chondrocytes: inhibition by Avocado-Soybean Unsaponifiables (ASU)

29 October 2018

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12 December 2020

SIRT1 variants are associated with aging in a healthy Han Chinese population

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12 December 2020

Potential involvement of SIRT1 in the pathogenesis of osteoarthritis through the modulation of chondrocyte gene expressions

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12 December 2020

The Sirt1 deacetylase modulates the insulin-like growth factor signaling pathway in mammals

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12 December 2020

Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells

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12 December 2020

The chemical biomarkers C2C, Coll2-1, and Coll2-1NO2 provide complementary information on type II collagen catabolism in healthy and osteoarthritic mice

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12 December 2020

sirt1-null mice develop an autoimmune-like condition

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12 December 2020

Identifiers

DOI

10.1002/ART.37750

1 reference

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17 February 2020

1 reference

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17 February 2020

1 reference

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