Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells (Q33930062)

30 July 2017

title

Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells (English)

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30 July 2017

10

Richard M Ransohoff

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30 July 2017

Zizhen Kang

1

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30 July 2017

Chenhui Wang

2

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30 July 2017

Jarod Zepp

3

1 reference

30 July 2017

Ling Wu

4

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30 July 2017

Kevin Sun

5

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30 July 2017

Junjie Zhao

6

1 reference

30 July 2017

Unni Chandrasekharan

7

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30 July 2017

Paul E DiCorleto

8

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30 July 2017

Bruce D Trapp

9

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30 July 2017

Xiaoxia Li

11

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30 July 2017

language of work or name

English

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publication date

1 September 2013

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30 July 2017

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30 July 2017

volume

16

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30 July 2017

issue

10

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30 July 2017

page(s)

1401-1408

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Molecular mechanisms of oligodendrocyte injury in multiple sclerosis and experimental autoimmune encephalomyelitis

30 July 2017

cites work

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5 July 2018

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5 July 2018

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CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Synergistic activity of interleukin-17 and tumor necrosis factor-α enhances oxidative stress-mediated oligodendrocyte apoptosis

5 July 2018

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Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis

5 July 2018

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IL-17RC is required for IL-17A- and IL-17F-dependent signaling and the pathogenesis of experimental autoimmune encephalomyelitis.

5 July 2018

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Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Remyelination in the CNS: from biology to therapy

5 July 2018

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Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma

5 July 2018

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IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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NG2 cells generate both oligodendrocytes and gray matter astrocytes.

5 July 2018

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5 July 2018

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Antigen presentation in autoimmunity and CNS inflammation: how T lymphocytes recognize the brain.

5 July 2018

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5 July 2018

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5 July 2018

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TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

5 July 2018

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Act1, a negative regulator in CD40- and BAFF-mediated B cell survival

5 July 2018

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Caspase-mediated oligodendrocyte cell death in the pathogenesis of autoimmune demyelination

5 July 2018

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

5 July 2018

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Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination

5 July 2018

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Role of NF kappa B activator Act1 in CD40-mediated signaling in epithelial cells

5 July 2018

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Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation.

5 July 2018

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Biology of oligodendrocyte and myelin in the mammalian central nervous system

5 July 2018

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CIKS, a connection to Ikappa B kinase and stress-activated protein kinase

5 July 2018

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Act1, an NF-kappa B-activating protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106025

Nuclear targeting defect of SMN lacking the C-terminus in a mouse model of spinal muscular atrophy

5 July 2018

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Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors

5 July 2018

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NG2+ glial cells: a novel glial cell population in the adult brain

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106025

Embryonic expression of myelin genes: evidence for a focal source of oligodendrocyte precursors in the ventricular zone of the neural tube

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106025

The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease.

5 July 2018

1 reference

Inhibition of transcription factor NF-κB in the central nervous system ameliorates autoimmune encephalomyelitis in mice

21 January 2018

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In vivo imaging of partially reversible th17 cell-induced neuronal dysfunction in the course of encephalomyelitis

21 January 2018

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Mice with conditional inactivation of fibroblast growth factor receptor-2 signaling in oligodendrocytes have normal myelin but display dramatic hyperactivity when combined with Cnp1 inactivation.

21 January 2018

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Progenitors in the adult cerebral cortex: Cell cycle properties and regulation by physiological stimuli and injury

21 January 2018

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Bax-ablation attenuates experimental autoimmune encephalomyelitis in mice

21 January 2018

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Isolation and culture of rat and mouse oligodendrocyte precursor cells.

21 January 2018

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An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization.

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106025

Multiple sclerosis: a two-stage disease

29 October 2018

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12 December 2020

Immunology of multiple sclerosis

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12 December 2020

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

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12 December 2020

Animal models of multiple sclerosis: the good, the bad and the bottom line

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12 December 2020

Identifiers

DOI

10.1038/NN.3505

1 reference

Dimensions Publication ID

30 July 2017

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1 reference

30 July 2017

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