Transport, metabolism and elimination mechanisms of anti-HIV agents (Q33933489)

30 July 2017

title

Transport, metabolism and elimination mechanisms of anti-HIV agents (English)

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30 July 2017

Li X

1

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30 July 2017

Chan WK

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

1 October 1999

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Advanced Drug Delivery Reviews

30 July 2017

published in

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30 July 2017

volume

39

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30 July 2017

issue

1-3

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30 July 2017

page(s)

81-103

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

30 July 2017

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7 January 2021

Pharmacokinetics of nevirapine: initial single-rising-dose study in humans

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7 January 2021

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7 January 2021

Current knowledge and future prospects for the use of HIV protease inhibitors

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7 January 2021

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7 January 2021

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7 January 2021

Hepatic and intestinal metabolism of indinavir, an HIV protease inhibitor, in rat and human microsomes. Major role of CYP3A

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7 January 2021

Nelfinavir. A review of its therapeutic efficacy in HIV infection

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir.

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7 January 2021

Saquinavir pharmacokinetics alone and in combination with nelfinavir in HIV-infected patients

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7 January 2021

Pharmacokinetic drug-drug interaction study of delavirdine and indinavir in healthy volunteers

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7 January 2021

Grapefruit juice enhances the bioavailability of the HIV protease inhibitor saquinavir in man

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7 January 2021

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7 January 2021

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7 January 2021

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Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice

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https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Interaction between grapefruit juice and midazolam in humans*

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Relationship between time of intake of grapefruit juice and its effect on pharmacokinetics and pharmacodynamics of felodipine in healthy subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Mechanism-based inactivation of human cytochrome P450 3A4 by grapefruit juice and red wine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

The pharmacokinetics of combination therapy with nelfinavir plus nevirapine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Lack of pharmacokinetic interaction between nelfinavir and nevirapine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Percutaneous absorption of 2',3'-dideoxyinosine in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Enhanced transdermal delivery of zidovudine in rats and human skin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Enhanced delivery of zidovudine through rat and human skin via ester prodrugs

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Extensive absorption of 2',3'-dideoxyinosine by intratracheal administration in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Biopharmaceutics of didanosine in humans and in a model for acid-labile drugs, the pentagastrin-pretreated dog

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Intestinal absorption and first-pass elimination of 2', 3'-dideoxynucleosides following oral administration in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Prodrugs of 2',3'-dideoxyinosine (DDI): improved oral bioavailability via hydrophobic esters

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Synthesis and pharmacokinetics of a dihydropyridine chemical delivery system for the antiimmunodeficiency virus agent dideoxycytidine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Synthesis and structure-activity relationships of 6-substituted 2',3'-dideoxypurine nucleosides as potential anti-human immunodeficiency virus agents

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Improved brain delivery of AZT using a glycosyl phosphotriester prodrug

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Dose-dependent brain delivery of zidovudine through the use of a zidovudine chemical delivery system

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Evaluation of a brain-targeting zidovudine chemical delivery system in dogs

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Brain targeting of anti-HIV nucleosides: synthesis and in vitro and in vivo studies of dihydropyridine derivatives of 3'-azido-2',3'-dideoxyuridine and 3'-azido-3'-deoxythymidine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Lipophilic halogenated congeners of 2',3'-dideoxypurine nucleosides active against human immunodeficiency virus in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Optimization of the local inhibition of intestinal adenosine deaminase (ADA) by erythro-9-(2-hydroxy-3-nonyl)adenine: enhanced oral delivery of an ADA-activated prodrug for anti-HIV therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Antiviral efficacy, intracellular uptake and pharmacokinetics of free and liposome-encapsulated 2',3'-dideoxyinosine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Lymphoid tissues targeting of liposome-encapsulated 2',3'-dideoxyinosine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Fc-receptor-mediated targeting of antibody-bearing liposomes containing dideoxycytidine triphosphate to human monocyte/macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Targeting of antiviral drugs to T4-lymphocytes. Anti-HIV activity of neoglycoprotein-AZTMP conjugates in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Synthesis and evaluation of 5′ alkyl ester prodrugs of zidovudine for directed lymphatic delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Inhibition of HIV in vitro by antiviral drug-targeting using nanoparticles

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Efficiency of nanoparticles as a carrier system for antiviral agents in human immunodeficiency virus-infected human monocytes/macrophages in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Ester prodrugs of zidovudine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Synthesis and biological evaluation of prodrugs of zidovudine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Prodrugs of 2',3'-didehydro-3'-deoxythymidine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Prodrugs of 2',3'-didehydro-3'-deoxythymidine (D4T): synthesis, antiviral activity, and rapid pharmacokinetic evaluation

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Preparation and evaluation of sustained release AZT-loaded microspheres: optimization of the release characteristics using response surface methodology.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Human red blood cells as bioreactors for the release of 2',3'-dideoxycytidine, an inhibitor of HIV infectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Plasma and cerebrospinal fluid pharmacokinetics of 3'-azido-3'-deoxythymidine: a novel pyrimidine analog with potential application for the treatment of patients with AIDS and related diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Stavudine: a review of its pharmacodynamic and pharmacokinetic properties and clinical potential in HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Pharmacokinetics, absolute bioavailability, and absorption characteristics of lamivudine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Saquinavir. A review of its pharmacology and clinical potential in the management of HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

Saquinavir. Clinical pharmacology and efficacy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

1 reference

7 January 2021

Single-dose pharmacokinetics of delavirdine mesylate and didanosine in patients with human immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900021-6

7 January 2021

10.1016/S0169-409X(99)00021-6

Identifiers

DOI

1 reference

30 July 2017

1 reference