Phosphorylated FADD induces NF-kappaB, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas (Q33933774)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16109772%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

Phosphorylated FADD induces NF-kappaB, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas (English)

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5 January 2020

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1 reference

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8

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Thomas Giordano

10

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author name string

Guoan Chen

1

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5 January 2020

Mahaveer S Bhojani

2

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Andrew C Heaford

3

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Daniel C Chang

4

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Bharathi Laxman

5

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Dafydd G Thomas

6

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Laura B Griffin

7

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Julia M Coppola

9

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Lin Lin

11

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David Adams

12

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Mark B Orringer

13

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5 January 2020

Brian D Ross

14

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David G Beer

15

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Alnawaz Rehemtulla

16

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5 January 2020

language of work or name

English

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publication date

18 August 2005

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Proceedings of the National Academy of Sciences of the United States of America

5 January 2020

published in

1 reference

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volume

102

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5 January 2020

issue

35

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page(s)

12507-12512

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Absence or low expression of fas-associated protein with death domain in acute myeloid leukemia cells predicts resistance to chemotherapy and poor outcome

5 January 2020

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Protein profiles associated with survival in lung adenocarcinoma

5 July 2018

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TRAIL and anti-tumor responses

5 July 2018

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Cell cycle effects by C-FADD depend on its C-terminal phosphorylation site.

5 July 2018

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The FADD is going nuclear.

5 July 2018

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Molecular evidence for the nuclear localization of FADD

5 July 2018

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The death effector domain protein family: regulators of cellular homeostasis

5 July 2018

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A Function of Fas-Associated Death Domain Protein in Cell Cycle Progression Localized to a Single Amino Acid at Its C-Terminal Region

5 July 2018

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Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosis

5 July 2018

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Cyclin D1 serves as a cell cycle regulatory switch in actively proliferating cells

5 July 2018

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NF-kappaB activation in cancer: a challenge for ubiquitination- and proteasome-based therapeutic approach

5 July 2018

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Gene-expression profiles predict survival of patients with lung adenocarcinoma

5 July 2018

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Discordant protein and mRNA expression in lung adenocarcinomas

5 July 2018

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IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

5 July 2018

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Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

5 July 2018

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Organ-specific molecular classification of primary lung, colon, and ovarian adenocarcinomas using gene expression profiles

5 July 2018

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T cell-specific FADD-deficient mice: FADD is required for early T cell development

5 July 2018

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Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C

5 July 2018

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FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation

5 July 2018

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Overexpression of cyclin B1 in early-stage non-small cell lung cancer and its clinical implication

5 July 2018

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LRDD, a novel leucine rich repeat and death domain containing protein

5 July 2018

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Activation of NF-kappaB by FADD, Casper, and caspase-8.

5 July 2018

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Phosphorylation of FADD/ MORT1 at serine 194 and association with a 70-kDa cell cycle-regulated protein kinase

5 July 2018

1 reference

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NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

5 July 2018

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Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

5 July 2018

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The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

5 July 2018

1 reference

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Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.

5 July 2018

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A role for FADD in T cell activation and development

5 July 2018

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Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

5 July 2018

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A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

5 July 2018

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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

5 July 2018

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A mouse Fas-associated protein with homology to the human Mort1/FADD protein is essential for Fas-induced apoptosis

5 July 2018

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FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

5 July 2018

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TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

5 July 2018

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5 July 2018

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Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

5 July 2018

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Cyclin D1 overexpression vs. retinoblastoma inactivation: implications for growth control evasion in non-small cell and small cell lung cancer

5 July 2018

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Members of the nuclear factor kappa B family transactivate the murine c-myb gene

5 July 2018

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FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

5 July 2018

1 reference

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A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

5 July 2018

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Transactivation of the c-myc promoter by human T cell leukemia virus type 1 tax is mediated by NF kappa B.

5 July 2018

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FADD-deficient T cells exhibit a disaccord in regulation of the cell cycle machinery

5 July 2018

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Crossref

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The requirements for Fas-associated death domain signaling in mature T cell activation and survival

21 January 2018

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Crossref

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Proteomic analysis of lung adenocarcinoma: identification of a highly expressed set of proteins in tumors.

21 January 2018

1 reference

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FADD is required for multiple signaling events downstream of the receptor Fas.

29 October 2018

1 reference

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The clinical significance of Cyclin B1 and Wee1 expression in non-small-cell lung cancer

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16109772

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12 December 2020

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Identifiers

DOI

10.1073/PNAS.0500397102

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5 January 2020

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https://api.fatcat.wiki/v0/release/octqrtrq3vgtritkfw5kdtnh54

mapped directly with Wikidata item

24 November 2022

based on heuristic

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16109772%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

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