NF-kappaB activation in cancer: a challenge for ubiquitination- and proteasome-based therapeutic approach (Q35036569)

5 August 2017

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title

NF-kappaB activation in cancer: a challenge for ubiquitination- and proteasome-based therapeutic approach (English)

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5 August 2017

protein ubiquitination

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1 reference

Sharon Amit

1

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PubMed ID

12507553

5 August 2017

Yinon Ben-Neriah

series ordinal

2

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5 August 2017

1 February 2003

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Seminars in Cancer Biology

5 August 2017

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5 August 2017

13

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5 August 2017

1

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5 August 2017

15-28

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Structure, regulation and function of NF-kappa B

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

NF-kappa B: ten years after

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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Series introduction: the transcription factor NF-kappaB and human disease

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

NF-kappaB signaling pathways in mammalian and insect innate immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Genetic approaches to study Rel/NF-kappa B/I kappa B function in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

NF-kappaB as a primary regulator of the stress response

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

The I kappa B kinase: a master regulator of NF-kappa B, innate immunity, and epidermal differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

I kappa B proteins: structure, function and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

SCF and Cullin/Ring H2-based ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Molecular dissection of the interactions among IkappaBalpha, FWD1, and Skp1 required for ubiquitin-mediated proteolysis of IkappaBalpha

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Phosphorylation of the PEST domain of IkappaBbeta regulates the function of NF-kappaB/IkappaBbeta complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

MAIL, a novel nuclear I kappa B protein that potentiates LPS-induced IL-6 production

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

A novel IkappaB protein, IkappaB-zeta, induced by proinflammatory stimuli, negatively regulates nuclear factor-kappaB in the nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

IkappaB family members function by different mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Characterization of IκBα Nuclear Import Pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IkappaBalpha

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Duration of nuclear NF-kappaB action regulated by reversible acetylation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Beta-catenin: a key mediator of Wnt signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Mechanisms of Wnt signaling in development

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Complex formation of adenomatous polyposis coli gene product and axin facilitates glycogen synthase kinase-3 beta-dependent phosphorylation of beta-catenin and down-regulates beta-catenin.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

WNT targets. Repression and activation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

The oncogenic activation of beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

beta-Catenin mutation and overexpression in hepatocellular carcinoma: clinicopathologic and prognostic significance.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Identification of FAP locus genes from chromosome 5q21

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Identification and characterization of the familial adenomatous polyposis coli gene

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Axin and hepatocellular carcinomas.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Rel/NF-kappa B and I kappa B factors in oncogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Aberrant rel/nfkb genes and activity in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Malignant transformation of primary chicken spleen cells by human transcription factor c-Rel

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Dependence of Dbl and Dbs transformation on MEK and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

The role of Rel/NF-kappa B proteins in viral oncogenesis and the regulation of viral transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

The molecular and cellular origins of Hodgkin's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Differential effects of Ras signaling through NFkappaB on skeletal myogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Members of the nuclear factor kappa B family transactivate the murine c-myb gene

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

INK4 cell cycle inhibitors direct transcriptional inactivation of NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Activators and target genes of Rel/NF-kappaB transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Three distinct signalling responses by murine fibroblasts to genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Twist is a potential oncogene that inhibits apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Sequence-specific transactivation of the Drosophila twist gene by the dorsal gene product

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Overexpression of the wild-type p53 gene inhibits NF-kappaB activity and synergizes with aspirin to induce apoptosis in human colon cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Transcriptional cross talk between NF-kappaB and p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Role of NF-κB in p53-mediated programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Increased sensitivity of CLL-derived lymphocytes to apoptotic death activation by the proteasome-specific inhibitor lactacystin

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

NF-κB-mediated Induction ofmdr1bExpression by Insulin in Rat Hepatoma Cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Increased and correlated nuclear factor-kappa B and Ku autoantigen activities are associated with development of multidrug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Angiogenesis: pathological, prognostic, and growth-factor pathways and their link to trial design and anticancer drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Genomic organization of human and mouse genes for vascular endothelial growth factor C.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Nuclear factor kappaB activity is essential for matrix metalloproteinase-1 and -3 upregulation in rabbit dermal fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

NF-kappaB activation and interleukin 6 production in fibroblasts by estrogen receptor-negative breast cancer cell-derived interleukin 1alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Cell adhesion molecules in the development and progression of malignant melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

The development of androgen-independent prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Estrogen receptor and breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

NF-kappaB inhibits apoptosis in murine mammary epithelia

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Mullerian inhibiting substance inhibits breast cancer cell growth through an NFkappa B-mediated pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Nuclear factor-kappaB (NF-kappaB) regulates proliferation and branching in mouse mammary epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

NF-kappaB and cell-cycle regulation: the cyclin connection

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Specific protection against breast cancers by cyclin D1 ablation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Reciprocal antagonism between estrogen receptor and NF-kappaB activity in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

The nuclear factor kappa B (NF-kappa B): a potential therapeutic target for estrogen receptor negative breast cancers

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Metalloproteinases: role in breast carcinogenesis, invasion and metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

The role of constitutive NF-kappaB activity in PC-3 human prostate cancer cell invasive behavior

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Inhibition of NF-kappaB, clonogenicity, and radiosensitivity of human cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Nuclear factor kappa B functions as a negative regulator for the rat androgen receptor gene and NF-kappa B activity increases during the age-dependent desensitization of the liver

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Negative regulation of MDR1 promoter activity in MCF-7, but not in multidrug resistant MCF-7/Adr, cells by cross-coupled NF-kappa B/p65 and c-Fos transcription factors and their interaction with the CAAT region

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Hodgkin's disease: a tumor with disturbed immunological pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Defective IkappaBalpha in Hodgkin cell lines with constitutively active NF-kappaB.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Autocrine and paracrine functions of cytokines in malignant lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

The Reed-Sternberg cell in classical Hodgkin's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Docetaxel and exisulind in hormone-refractory prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Inhibition of NF-kappa B by sodium salicylate and aspirin

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Is NF-kappaB the sensor of oxidative stress?

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Intravenous injection of oligodeoxynucleotides to the NF-kappaB binding site inhibits hepatic metastasis of M5076 reticulosarcoma in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Suppressed severity of collagen-induced arthritis by in vivo transfection of nuclear factor kappaB decoy oligodeoxynucleotides as a gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Proteasome inhibition: a novel approach to cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Proteasome inhibition in cancer: development of PS-341.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

NF-kappa B as a therapeutic target in multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

Inhibition of HOS expression and activities by Wnt pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

High susceptibility to bacterial infection, but no liver dysfunction, in mice compromised for hepatocyte NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900096-2

7 January 2021

10.1016/S1044-579X(02)00096-2

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12507553