Chromosome stability, DNA recombination and the BRCA2 tumour suppressor (Q33946025)

30 July 2017

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title

Chromosome stability, DNA recombination and the BRCA2 tumour suppressor (English)

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30 July 2017

Venkitaraman AR

1

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30 July 2017

1 June 2001

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Current Opinion in Cell Biology

30 July 2017

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30 July 2017

13

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30 July 2017

338-343

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30 July 2017

3

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THE GENETICS OF BREAST CANCER SUSCEPTIBILITY

30 July 2017

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Internal repeats in the BRCA2 protein sequence

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Involvement of Brca2 in DNA repair

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Brca2 is required for embryonic cellular proliferation in the mouse

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

The breast cancer susceptibility gene, BRCA2: at the crossroads between DNA replication and recombination?

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Recombinational crossroads: eukaryotic enzymes and the limits of bacterial precedents

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Initiation of genetic recombination and recombination-dependent replication

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

The importance of repairing stalled replication forks

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

BRCA2 is required for homology-directed repair of chromosomal breaks

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Truncated BRCA2 is cytoplasmic: implications for cancer-linked mutations

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

In search of the tumour-suppressor functions of BRCA1 and BRCA2

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

DNA double-strand breaks caused by replication arrest

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

RuvAB acts at arrested replication forks

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Killing the umpire: cooperative defects in mitotic checkpoint and BRCA2 genes on the road to transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

BRCA2 associates with acetyltransferase activity when bound to P/CAF

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

The BRCA2 activation domain associates with and is phosphorylated by a cellular protein kinase

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

Insights into the functions of BRCA1 and BRCA2.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900217-9

7 January 2021

10.1016/S0955-0674(00)00217-9

Identifiers

DOI

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30 July 2017

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PubMed ID

11343905